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Protein

Uncharacterized WD repeat-containing protein C17D11.08

Gene

SPBC17D11.08

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized WD repeat-containing protein C17D11.08
Gene namesi
ORF Names:SPBC17D11.08
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC17D11.08.
PomBaseiSPBC17D11.08.

Subcellular locationi

GO - Cellular componenti

  • Cul4-RING E3 ubiquitin ligase complex Source: PomBase
  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • Golgi apparatus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 435435Uncharacterized WD repeat-containing protein C17D11.08PRO_0000316548Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei266 – 2661Phosphoserine1 Publication
Modified residuei388 – 3881Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO74763.

PTM databases

iPTMnetiO74763.

Interactioni

Protein-protein interaction databases

BioGridi276172. 19 interactions.
MINTiMINT-4680565.

Structurei

3D structure databases

ProteinModelPortaliO74763.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati105 – 14945WD 1Add
BLAST
Repeati164 – 20441WD 2Add
BLAST
Repeati207 – 24741WD 3Add
BLAST
Repeati313 – 35341WD 4Add
BLAST

Sequence similaritiesi

Contains 4 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000260968.
InParanoidiO74763.
KOiK11805.
OMAiSSEWIAM.
OrthoDBiEOG7K9KD0.
PhylomeDBiO74763.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74763-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLRRNRYS ISAGVGKSVL DSLGKFYGSP KRQLPNKFEA GKEYTGYNAP
60 70 80 90 100
WIPFALDWLK QGKYSSEWIA MGSLNEEPNN MIQLLKLITG DDGNSHLEKA
110 120 130 140 150
QAATDLEYPV TKLLWNPSSV GSNTDSQLLA STDQQLRLWK TDFEAGIDSP
160 170 180 190 200
LLCQASLSTH VKTHNNAPLT SFDWCKTDPS YIVVSSLDTT CTVWDIVAQQ
210 220 230 240 250
SKTQLIAHDK EVYDVAFLKD SINVFVSVGA DGSVRMFDLR SLDHSTIIYE
260 270 280 290 300
GDSTFWKRNG DYTNASPPVS APLLRLSACD SDVNLMATFH HNSSDVQMID
310 320 330 340 350
IRVPGTAYAT LRGHKGDVNA VKWMPGSKSK LATCGDDCVV SLWDLDQPVN
360 370 380 390 400
PSPAPTLSVS GTTPGMTGST SEYVTPVSSV NSMRETASPL NADNQYSPLL
410 420 430
SWKLEHEVNN LSWSVKNDGL AVVYGKSLEI LKVPQ
Length:435
Mass (Da):47,743
Last modified:November 1, 1998 - v1
Checksum:iEC48C5ACEA9DA6D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21079.1.
PIRiT39719.
RefSeqiNP_596382.1. NM_001022303.2.

Genome annotation databases

EnsemblFungiiSPBC17D11.08.1; SPBC17D11.08.1:pep; SPBC17D11.08.
GeneIDi2539614.
KEGGispo:SPBC17D11.08.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21079.1.
PIRiT39719.
RefSeqiNP_596382.1. NM_001022303.2.

3D structure databases

ProteinModelPortaliO74763.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276172. 19 interactions.
MINTiMINT-4680565.

PTM databases

iPTMnetiO74763.

Proteomic databases

MaxQBiO74763.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC17D11.08.1; SPBC17D11.08.1:pep; SPBC17D11.08.
GeneIDi2539614.
KEGGispo:SPBC17D11.08.

Organism-specific databases

EuPathDBiFungiDB:SPBC17D11.08.
PomBaseiSPBC17D11.08.

Phylogenomic databases

HOGENOMiHOG000260968.
InParanoidiO74763.
KOiK11805.
OMAiSSEWIAM.
OrthoDBiEOG7K9KD0.
PhylomeDBiO74763.

Miscellaneous databases

NextBioi20800771.
PROiO74763.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-266 AND SER-388, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiYBE8_SCHPO
AccessioniPrimary (citable) accession number: O74763
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.