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Protein

Mannan polymerase II complex anp1 subunit

Gene

anp1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins.By similarity

GO - Biological processi

Complete GO annotation...

Protein family/group databases

CAZyiGT62. Glycosyltransferase Family 62.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan polymerase II complex anp1 subunit
Short name:
M-Pol II subunit anp1
Gene namesi
Name:anp1
ORF Names:SPBC1734.04
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1734.04.
PomBaseiSPBC1734.04. anp1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3737CytoplasmicSequence analysisAdd
BLAST
Transmembranei38 – 5720Helical; Signal-anchor for type II membrane proteinSequence analysisAdd
BLAST
Topological domaini58 – 430373LumenalSequence analysisAdd
BLAST

GO - Cellular componenti

  • alpha-1,6-mannosyltransferase complex Source: PomBase
  • endoplasmic reticulum Source: PomBase
  • endoplasmic reticulum membrane Source: UniProtKB-SubCell
  • Golgi apparatus Source: PomBase
  • Golgi cis cisterna Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 430430Mannan polymerase II complex anp1 subunitPRO_0000193673Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi122 – 1221N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiO74745.

Interactioni

Subunit structurei

Component of the M-Pol II complex.By similarity

Protein-protein interaction databases

BioGridi276240. 2 interactions.
MINTiMINT-4680396.

Family & Domainsi

Sequence similaritiesi

Belongs to the ANP1/MMN9/VAN1 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000167461.
InParanoidiO74745.
KOiK05533.
OMAiVEYPATI.
OrthoDBiEOG73V6VP.
PhylomeDBiO74745.

Family and domain databases

InterProiIPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 2 hits.

Sequencei

Sequence statusi: Complete.

O74745-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKANRDFGRD GGPFSITPNR FQPKSSGNPI FRQKTIRTVG IIALTLVLFL
60 70 80 90 100
FFHRSFFSSF GEFPSFSSTA NAPNSDVQEY DLRKVMNAKF TGDYSPKEKV
110 120 130 140 150
LICAPLRNAA EHLNMFFGHM NNLTYPHELI DLAFLISDTD DNTLEVLKQH
160 170 180 190 200
LDAIQNDEDE SKHFNNVLIM LKDFGAIFGQ EFSDRHGFAA QGPRRKLMAR
210 220 230 240 250
ARNWLLSAAI QPYHSWVYWR DVDVETAPNT ILEDLMRHDK DIIVPNVYRP
260 270 280 290 300
LPDWLGNEQP YDLNSWAESE TALQLADTLG EDDVIVEGYA EYATWRPHLA
310 320 330 340 350
YLRDPNGDPS VEMPLDGIGG VSIMSKAKVH LEGCEFPAFS FEKHAETEGF
360 370 380 390 400
GKMAKRMGFS VYGLPHYVIW HIYEPSDDDK RIMAEMERER KEREAAELEE
410 420 430
AKKYQTAGFT QPDDQGAEEG PLAHADDHVD
Length:430
Mass (Da):48,991
Last modified:November 1, 1998 - v1
Checksum:i48A48634005F6C66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21290.1.
AB028011 Genomic DNA. Translation: BAA87315.1.
PIRiT39651.
RefSeqiNP_595421.2. NM_001021328.3.

Genome annotation databases

EnsemblFungiiSPBC1734.04.1; SPBC1734.04.1:pep; SPBC1734.04.
GeneIDi2539685.
KEGGispo:SPBC1734.04.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21290.1.
AB028011 Genomic DNA. Translation: BAA87315.1.
PIRiT39651.
RefSeqiNP_595421.2. NM_001021328.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276240. 2 interactions.
MINTiMINT-4680396.

Protein family/group databases

CAZyiGT62. Glycosyltransferase Family 62.

Proteomic databases

MaxQBiO74745.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC1734.04.1; SPBC1734.04.1:pep; SPBC1734.04.
GeneIDi2539685.
KEGGispo:SPBC1734.04.

Organism-specific databases

EuPathDBiFungiDB:SPBC1734.04.
PomBaseiSPBC1734.04. anp1.

Phylogenomic databases

HOGENOMiHOG000167461.
InParanoidiO74745.
KOiK05533.
OMAiVEYPATI.
OrthoDBiEOG73V6VP.
PhylomeDBiO74745.

Miscellaneous databases

PROiO74745.

Family and domain databases

InterProiIPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
    Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
    Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 214-414, SUBCELLULAR LOCATION.
    Strain: ATCC 38364 / 968.
  3. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  4. "The actomyosin ring recruits early secretory compartments to the division site in fission yeast."
    Vjestica A., Tang X.Z., Oliferenko S.
    Mol. Biol. Cell 19:1125-1138(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiANP1_SCHPO
AccessioniPrimary (citable) accession number: O74745
Secondary accession number(s): Q9US67
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: November 1, 1998
Last modified: June 8, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.