O74745 (YHF4_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C1734.04

Gene names

ORF Names:

SPBC1734.04

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	430 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Single-pass type II membrane protein Probable Ref.2.
Sequence similarities	Belongs to the ANP1/MMN9/VAN1 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein N-linked glycosylation Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Cellular component	Golgi trans cisterna Inferred from direct assay. Source: GeneDB_Spombe alpha-1,6-mannosyltransferase complex Inferred from sequence or structural similarity. Source: GeneDB_Spombe endoplasmic reticulum Inferred from direct assay. Source: GeneDB_Spombe integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 430	430	Uncharacterized protein C1734.04		PRO_0000193673
Regions
	Topological domain	1 – 37	37	Cytoplasmic Potential
	Transmembrane	38 – 57	20	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	58 – 430	373	Lumenal Potential
Amino acid modifications
	Glycosylation	122	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	O74745 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 48A48634005F6C66	FASTA	430	48,991
	10 20 30 40 50 60 MKANRDFGRD GGPFSITPNR FQPKSSGNPI FRQKTIRTVG IIALTLVLFL FFHRSFFSSF 70 80 90 100 110 120 GEFPSFSSTA NAPNSDVQEY DLRKVMNAKF TGDYSPKEKV LICAPLRNAA EHLNMFFGHM 130 140 150 160 170 180 NNLTYPHELI DLAFLISDTD DNTLEVLKQH LDAIQNDEDE SKHFNNVLIM LKDFGAIFGQ 190 200 210 220 230 240 EFSDRHGFAA QGPRRKLMAR ARNWLLSAAI QPYHSWVYWR DVDVETAPNT ILEDLMRHDK 250 260 270 280 290 300 DIIVPNVYRP LPDWLGNEQP YDLNSWAESE TALQLADTLG EDDVIVEGYA EYATWRPHLA 310 320 330 340 350 360 YLRDPNGDPS VEMPLDGIGG VSIMSKAKVH LEGCEFPAFS FEKHAETEGF GKMAKRMGFS 370 380 390 400 410 420 VYGLPHYVIW HIYEPSDDDK RIMAEMERER KEREAAELEE AKKYQTAGFT QPDDQGAEEG 430 PLAHADDHVD

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library." Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y. Genes Cells 5:169-190(2000) [PubMed: 10759889] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 214-414, SUBCELLULAR LOCATION. Strain: ATCC 38364 / 968.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329671 Genomic DNA. Translation: CAA21290.1. AB028011 Genomic DNA. Translation: BAA87315.1.
PIR	T39651.
RefSeq	NP_595421.2. NM_001021328.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O74745.
Protein family/group databases
CAZy	GT62. Glycosyltransferase Family 62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPBC1734.04.1; SPBC1734.04.1:pep; SPBC1734.04.
GeneID	2539685.
KEGG	spo:SPBC1734.04.
Organism-specific databases
GeneDB_Spombe	SPBC1734.04.
Phylogenomic databases
eggNOG	fuNOG05235.
GeneTree	EFGT00050000002721.
HOGENOM	HBG323986.
OrthoDB	EOG4GF6PR.
Enzyme and pathway databases
BioCyc	SPOM-XXX-01:SPOM-XXX-01-003732-MONOMER.
Gene expression databases
ArrayExpress	O74745.
Family and domain databases
InterPro	IPR005109. Anp1. [Graphical view]
KO	K05533.
Pfam	PF03452. Anp1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YHF4_SCHPO

Accession

Primary (citable) accession number: O74745
Secondary accession number(s): Q9US67

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 23, 2003
Last sequence update:	November 1, 1998
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program