O74660 (ALS4_CANAX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Agglutinin-like protein 4

Gene names

Name:

ALS4

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	469 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Function	May play a role in adhesion and pathogenesis.
Post-translational modification	N-glycosylated and O-glycosylated Potential.

Ontologies

Keywords
Biological process	Cell adhesion
Domain	Repeat Signal
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential
	Chain	18 – ›469	›452	Agglutinin-like protein 4		PRO_0000020694
Experimental info
	Non-terminal residue	469	1

Sequences

	Sequence		Length	Mass (Da)
	O74660 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 0EDCAB19B89EFCB1	FASTA	469	49,604
	10 20 30 40 50 60 MLLQFLLLSL CVSVATAKVI TGVFNSFNSL TWANAASYPY RGPATPTWTA VIGWSLDGAT 70 80 90 100 110 120 ASAGDTFTLD MPCVFKFITD QTSIDLVADG RTYATCNLNS AEEFTTFSSV SCTVTTTMTA 130 140 150 160 170 180 DTKAIGTVTL PFSFSVGGSG SDVDLANSQC FTAGINTVTF NDGDTSISTT VDFEKSTVAS 190 200 210 220 230 240 SDRILLSRIL PSLSQAVNLF LPQECANGYT SGTMGFSTAG TGATIDCSTV HVGISNGLND 250 260 270 280 290 300 WNYPISSESF SYTKTCTSTS VLVTFQNVPA GYRPFVDAYI SATRVSSYTM QYTNIYACVG 310 320 330 340 350 360 AASVDDSFTH TWRGYSNSQA GSNGITIVVT TRTVTDSTTA VTTLPFNSDT DKTKTIEILQ 370 380 390 400 410 420 PIPTTTITTS YVGVTTSYST KTAPIGETAT VIVDVPYHTT TTVTSEWTGT ITTTTTRTNP 430 440 450 460 TDSIDTVVVQ VPSPNPTVTT TEYWSQSYAT TTTVTAPPGG TDSVIIREP

References

[1]	"Identification of Candida albicans ALS2 and ALS4 and localization of als proteins to the fungal cell surface." Hoyer L.L., Payne T.L., Hecht J.E. J. Bacteriol. 180:5334-5343(1998) [PubMed: 9765564] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 1161.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF024584 Genomic DNA. Translation: AAC64239.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR008966. Adhesion_bac. IPR008440. Agglutinin-like_ALS_rpt. IPR024672. Agglutinin-like_N. [Graphical view]
Pfam	PF05792. Candida_ALS. 3 hits. PF11766. Candida_ALS_N. 1 hit. [Graphical view]
SUPFAM	SSF49401. Adhes_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALS4_CANAX

Accession

Primary (citable) accession number: O74660

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	November 1, 1998
Last modified:	October 19, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program