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Reviewed, UniProtKB/Swiss-Prot O74623 (ALS3_CANAL)

Last modified November 24, 2009. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Agglutinin-like protein 3
Gene names
Name: ALS3
OrganismCandida albicans (Yeast)
Taxonomic identifier5476 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

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Protein attributes

Sequence length1119 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted.

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General annotation (Comments)

Function

May play a role in adhesion and pathogenesis.

Post-translational modification

N-glycosylated and O-glycosylated Potential.

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Ontologies

Keywords
   Biological processCell adhesion
   DomainRepeat
Signal
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processcell adhesion

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionprotein binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 11191102Agglutinin-like protein 3
PRO_0000020693

Regions

Repeat433 – 468361-1
Repeat469 – 504361-2
Repeat505 – 540361-3
Repeat541 – 576361-4
Repeat577 – 612361-5
Repeat613 – 648361-6
Repeat649 – 684361-7
Repeat685 – 720361-8
Repeat721 – 756361-9
Repeat757 – 792361-10
Region433 – 79236010 X 36 AA tandem repeats
Compositional bias399 – 4046Poly-Thr
Compositional bias450 – 4556Poly-Thr
Compositional bias557 – 5637Poly-Thr
Compositional bias593 – 5975Poly-Thr
Compositional bias630 – 6356Poly-Thr
Compositional bias666 – 6716Poly-Thr
Compositional bias702 – 7076Poly-Thr
Compositional bias738 – 7436Poly-Thr
Compositional bias774 – 7774Poly-Thr
Compositional bias1044 – 10474Poly-Thr

Amino acid modifications

Glycosylation4711N-linked (GlcNAc...) Potential
Glycosylation5431N-linked (GlcNAc...) Potential
Glycosylation5791N-linked (GlcNAc...) Potential
Glycosylation6511N-linked (GlcNAc...) Potential
Glycosylation6871N-linked (GlcNAc...) Potential
Glycosylation7231N-linked (GlcNAc...) Potential
Glycosylation7591N-linked (GlcNAc...) Potential
Glycosylation8451N-linked (GlcNAc...) Potential
Glycosylation9871N-linked (GlcNAc...) Potential
Glycosylation10501N-linked (GlcNAc...) Potential
Glycosylation10611N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
O74623-1 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 6A3FB3FC8C879A71

FASTA1,119119,927
        10         20         30         40         50         60 
MLQQYTLLLI YLSVATAKTI TGVFNSFNSL TWSNAATYNY KGPGTPTWNA VLGWSLDGTS 

        70         80         90        100        110        120 
ASPGDTFTLN MPCVFKFTTS QTSVDLTAHG VKYATCQFQA GEEFMTFSTL TCTVSNTLTP 

       130        140        150        160        170        180 
SIKALGTVTL PLAFNVGGTG SSVDLEDSKC FTAGTNTVTF NDGGKKISIN VDFERSNVDP 

       190        200        210        220        230        240 
KGYLTDSRVI PSLNKVSTLF VAPQCANGYT SGTMGFANTY GDVQIDCSNI HVGITKGLND 

       250        260        270        280        290        300 
WNYPVSSESF SYTKTCSSNG IFITYKNVPA GYRPFVDAYI SATDVNSYTL SYANEYTCAG 

       310        320        330        340        350        360 
GYWQRAPFTL RWTGYRNSDA GSNGIVIVAT TRTVTDSTTA VTTLPFDPNR DKTKTIEILK 

       370        380        390        400        410        420 
PIPTTTITTS YVGVTTSYST KTAPIGETAT VIVDIPYHTT TTVTSKWTGT ITSTTTHTNP 

       430        440        450        460        470        480 
TDSIDTVIVQ VPSPNPTVTT TEYWSQSFAT TTTITGPPGN TDTVLIREPP NHTVTTTEYW 

       490        500        510        520        530        540 
SESYTTTSTF TAPPGGTDSV IIKEPPNPTV TTTEYWSESY TTTSTFTAPP GGTDSVIIKE 

       550        560        570        580        590        600 
PPNHTVTTTE YWSQSYTTTT TVTAPPGGTD TVLVREPPNH TVTTTEYWSQ SYTTTTTVIA 

       610        620        630        640        650        660 
PPGGTDSVII REPPNPTVTT TEYWSQSYAT TTTITAPPGE TDTVLIREPP NHTVTTTEYW 

       670        680        690        700        710        720 
SQSYATTTTI TAPPGETDTV LIREPPNHTV TTTEYWSQSF ATTTTVTAPP GGTDTVIIRE 

       730        740        750        760        770        780 
PPNHTVTTTE YWSQSYATTT TITAPPGETD TVLIREPPNH TVTTTEYWSQ SYATTTTIIA 

       790        800        810        820        830        840 
PPGETDTVLI REPPNPTVTT TEYWSQSYTT ATTVTAPPGG TDTVIIYDTM SSSEISSFSR 

       850        860        870        880        890        900 
PHYTNHTTLW STTWVIETKT ITETSCEGDK GCSWVSVSTR IVTIPNNIET PMVTNTVDST 

       910        920        930        940        950        960 
TTESTSQSPS GIFSESGVSV ETESSTVTTA QTNPSVPTTE SEVVFTTKGN NENGPYESPS 

       970        980        990       1000       1010       1020 
TNVKSSMDEN SEFTTSTAAS TSTDIENETI ATTGSVEASS PIISSSADET TTVTTTAEST 

      1030       1040       1050       1060       1070       1080 
SVIEQPTNNN GGGKAPSATS SPSTTTTANN DSVITGTTST NQSQSQSQYN SDTQQTTLSQ 

      1090       1100       1110 
QMTSSLVSLH MLTTFDGSGS VIQHSTWLCG LITLLSLFI

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References

[1]"Candida albicans ALS3 and insights into the nature of the ALS gene family."
Hoyer L.L., Payne T.L., Bell M., Myers A.M., Scherer S.
Curr. Genet. 33:451-459(1998) [PubMed: 9644209] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 1161.

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Cross-references

Sequence databases

U87956 Genomic DNA. Translation: AAC39486.1.

3D structure databases

ModBaseSearch...

Family and domain databases

InterProIPR008966. Adhesion_bac.
IPR008440. Candida_ALS.
[Graphical view]
PfamPF05792. Candida_ALS. 2 hits.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameALS3_CANAL
AccessionPrimary (citable) accession number: O74623
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: November 24, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

Candida albicans

Candida albicans: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents