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Protein

Set1 complex component spp1

Gene

spp1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri118 – 168PHD-typePROSITE-ProRule annotationAdd BLAST51

GO - Molecular functioni

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • regulation of histone H3-K4 methylation Source: PomBase

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component spp1
Short name:
Set1C component spp1
Alternative name(s):
COMPASS component spp1
Complex proteins associated with set1 protein spp1
Gene namesi
Name:spp1
ORF Names:SPCC594.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC594.05c
PomBaseiSPCC594.05c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000593371 – 424Set1 complex component spp1Add BLAST424

Proteomic databases

MaxQBiO74508
PaxDbiO74508
PRIDEiO74508

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.2 Publications

Protein-protein interaction databases

BioGridi275596193 interactors.
STRINGi4896.SPCC594.05c.1

Structurei

3D structure databases

ProteinModelPortaliO74508
SMRiO74508
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri118 – 168PHD-typePROSITE-ProRule annotationAdd BLAST51

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiO74508
KOiK14960
OMAiTWKRKCR
OrthoDBiEOG092C1PYH
PhylomeDBiO74508

Family and domain databases

Gene3Di3.30.40.101 hit
InterProiView protein in InterPro
IPR037869 Spp1
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR12321:SF97 PTHR12321:SF97, 2 hits
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

O74508-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELTQENTEE NEKTHVESIV KFEDSNRGTI TDFHIETANN EEEKDANVIL
60 70 80 90 100
NKSVKMEVEE VNGHVDSSST ETDIEMQVIQ QPTIPKKPPV SAHRRGPRKH
110 120 130 140 150
RGNANSQLNL STADHQRPLY CICQKPDDGS WMLGCDGCED WFHGTCVNIP
160 170 180 190 200
ESYNDLTVQY FCPKCTEEGK GITTWKRKCR LRECSNPTRP NSNYCSDKHG
210 220 230 240 250
VDFFREKVKL STVEPSAIKN LVLFAKKREE FQNLGTVGPT LPSQVPPEVV
260 270 280 290 300
YNFEIEEANR LNAEIVQLNK EKEVASNKKI FLQLIKDSSR RAVLAYKERE
310 320 330 340 350
GIKKDLCGFD SRLLFNQQQM NELWEKVSNG APLSLDMSID PSPESTCFTE
360 370 380 390 400
KRRCAKHTSW QVIFTEDFEL QESNILQKLN MKQTAKDVML EHQKQRCLPG
410 420
IQYDGYARFC HEQLSPEKMA NLLK
Length:424
Mass (Da):48,683
Last modified:November 1, 1998 - v1
Checksum:i2963605C3DFCC0B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20664.1
PIRiT41449
RefSeqiNP_587791.1, NM_001022784.2

Genome annotation databases

EnsemblFungiiSPCC594.05c.1; SPCC594.05c.1:pep; SPCC594.05c
GeneIDi2539023
KEGGispo:SPCC594.05c

Entry informationi

Entry nameiSPP1_SCHPO
AccessioniPrimary (citable) accession number: O74508
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome