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Protein

Set1 complex component spp1

Gene

spp1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri118 – 16851PHD-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • regulation of histone H3-K4 methylation Source: PomBase
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component spp1
Short name:
Set1C component spp1
Alternative name(s):
COMPASS component spp1
Complex proteins associated with set1 protein spp1
Gene namesi
Name:spp1
ORF Names:SPCC594.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC594.05c.
PomBaseiSPCC594.05c.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nuclear chromatin Source: PomBase
  • nucleus Source: PomBase
  • Set1C/COMPASS complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 424424Set1 complex component spp1PRO_0000059337Add
BLAST

Proteomic databases

MaxQBiO74508.

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.2 Publications

Protein-protein interaction databases

BioGridi275596. 192 interactions.
MINTiMINT-4679659.

Structurei

3D structure databases

ProteinModelPortaliO74508.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PHD-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri118 – 16851PHD-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiO74508.
KOiK14960.
OMAiTWKRKCR.
OrthoDBiEOG092C1PYH.
PhylomeDBiO74508.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74508-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELTQENTEE NEKTHVESIV KFEDSNRGTI TDFHIETANN EEEKDANVIL
60 70 80 90 100
NKSVKMEVEE VNGHVDSSST ETDIEMQVIQ QPTIPKKPPV SAHRRGPRKH
110 120 130 140 150
RGNANSQLNL STADHQRPLY CICQKPDDGS WMLGCDGCED WFHGTCVNIP
160 170 180 190 200
ESYNDLTVQY FCPKCTEEGK GITTWKRKCR LRECSNPTRP NSNYCSDKHG
210 220 230 240 250
VDFFREKVKL STVEPSAIKN LVLFAKKREE FQNLGTVGPT LPSQVPPEVV
260 270 280 290 300
YNFEIEEANR LNAEIVQLNK EKEVASNKKI FLQLIKDSSR RAVLAYKERE
310 320 330 340 350
GIKKDLCGFD SRLLFNQQQM NELWEKVSNG APLSLDMSID PSPESTCFTE
360 370 380 390 400
KRRCAKHTSW QVIFTEDFEL QESNILQKLN MKQTAKDVML EHQKQRCLPG
410 420
IQYDGYARFC HEQLSPEKMA NLLK
Length:424
Mass (Da):48,683
Last modified:November 1, 1998 - v1
Checksum:i2963605C3DFCC0B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20664.1.
PIRiT41449.
RefSeqiNP_587791.1. NM_001022784.2.

Genome annotation databases

EnsemblFungiiSPCC594.05c.1; SPCC594.05c.1:pep; SPCC594.05c.
GeneIDi2539023.
KEGGispo:SPCC594.05c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20664.1.
PIRiT41449.
RefSeqiNP_587791.1. NM_001022784.2.

3D structure databases

ProteinModelPortaliO74508.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275596. 192 interactions.
MINTiMINT-4679659.

Proteomic databases

MaxQBiO74508.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC594.05c.1; SPCC594.05c.1:pep; SPCC594.05c.
GeneIDi2539023.
KEGGispo:SPCC594.05c.

Organism-specific databases

EuPathDBiFungiDB:SPCC594.05c.
PomBaseiSPCC594.05c.

Phylogenomic databases

InParanoidiO74508.
KOiK14960.
OMAiTWKRKCR.
OrthoDBiEOG092C1PYH.
PhylomeDBiO74508.

Miscellaneous databases

PROiO74508.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPP1_SCHPO
AccessioniPrimary (citable) accession number: O74508
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.