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Protein

U6 snRNA-associated Sm-like protein LSm7

Gene

lsm7

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Probable component of the spliceosome.

GO - Molecular functioni

  • poly(U) RNA binding Source: PomBase
  • RNA binding Source: PomBase

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, RNA-binding
Biological processmRNA processing, mRNA splicing, rRNA processing, tRNA processing

Enzyme and pathway databases

ReactomeiR-SPO-430039 mRNA decay by 5' to 3' exoribonuclease

Names & Taxonomyi

Protein namesi
Recommended name:
U6 snRNA-associated Sm-like protein LSm7
Gene namesi
Name:lsm7
ORF Names:SPCC285.12
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC285.12
PomBaseiSPCC285.12 lsm7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003173081 – 113U6 snRNA-associated Sm-like protein LSm7Add BLAST113

Proteomic databases

MaxQBiO74499
PaxDbiO74499
PRIDEiO74499

PTM databases

iPTMnetiO74499

Interactioni

Protein-protein interaction databases

BioGridi275538, 7 interactors
STRINGi4896.SPCC285.12.1

Structurei

Secondary structure

1113
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi34 – 40Combined sources7
Beta strandi45 – 53Combined sources9
Beta strandi59 – 67Combined sources9
Turni71 – 73Combined sources3
Beta strandi80 – 88Combined sources9
Turni90 – 92Combined sources3
Beta strandi93 – 98Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3SWNX-ray2.50C/F/O/R1-113[»]
4EMKX-ray2.30C1-113[»]
ProteinModelPortaliO74499
SMRiO74499
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO74499

Family & Domainsi

Sequence similaritiesi

Belongs to the snRNP Sm proteins family.Curated

Phylogenomic databases

HOGENOMiHOG000223548
InParanoidiO74499
KOiK12626
OMAiGPKREAI
OrthoDBiEOG092C5VL3
PhylomeDBiO74499

Family and domain databases

CDDicd01729 LSm7, 1 hit
InterProiView protein in InterPro
IPR017132 Lsm7
IPR001163 LSM_dom_euk/arc
IPR010920 LSM_dom_sf
PfamiView protein in Pfam
PF01423 LSM, 1 hit
SMARTiView protein in SMART
SM00651 Sm, 1 hit
SUPFAMiSSF50182 SSF50182, 1 hit

Sequencei

Sequence statusi: Complete.

O74499-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLQKRPGP GNSSQPTERP RKESILDLSR YQDQRIQATF TGGRQITGIL
60 70 80 90 100
KGFDQLMNLV LDDVEEQLRN PEDGKLTGAI RKLGLVVVRG TTLVLIAPMD
110
GSEEIPNPFV QAE
Length:113
Mass (Da):12,474
Last modified:November 1, 1998 - v1
Checksum:i4B257009949187E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20851.1
PIRiT41258
RefSeqiNP_588340.1, NM_001023331.2

Genome annotation databases

EnsemblFungiiSPCC285.12.1; SPCC285.12.1:pep; SPCC285.12
GeneIDi2538964
KEGGispo:SPCC285.12

Similar proteinsi

Entry informationi

Entry nameiLSM7_SCHPO
AccessioniPrimary (citable) accession number: O74499
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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