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Protein

ATP synthase subunit 5, mitochondrial

Gene

atp5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha3beta3 subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit 5, mitochondrial
Short name:
ATP synthase chain 5
Alternative name(s):
Oligomycin sensitivity conferral protein
Short name:
OSCP
Gene namesi
Name:atp5
ORF Names:SPCC1840.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1840.06.
PomBaseiSPCC1840.06. atp5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000002655? – 216ATP synthase subunit 5, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiO74479.
PRIDEiO74479.

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c (By similarity).By similarity

Protein-protein interaction databases

BioGridi275811. 1 interactor.
MINTiMINT-4679440.

Structurei

3D structure databases

ProteinModelPortaliO74479.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase delta chain family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000075825.
InParanoidiO74479.
KOiK02137.
OMAiMNPHVKR.
OrthoDBiEOG092C4VM2.
PhylomeDBiO74479.

Family and domain databases

Gene3Di1.10.520.20. 1 hit.
HAMAPiMF_01416. ATP_synth_delta_bact. 1 hit.
InterProiIPR026015. ATP_synth_OSCP/delta_N.
IPR000711. ATPase_OSCP/dsu.
[Graphical view]
PANTHERiPTHR11910. PTHR11910. 1 hit.
PfamiPF00213. OSCP. 1 hit.
[Graphical view]
PRINTSiPR00125. ATPASEDELTA.
SUPFAMiSSF47928. SSF47928. 1 hit.
TIGRFAMsiTIGR01145. ATP_synt_delta. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O74479-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNHIFRRSIP ITARLPSLGI RSLATATASA HPPVQLYGLD GSYASSLYTA
60 70 80 90 100
AVKESKLDNV EKALNKLSGV LQQRPEFEQY ISSPWLTRED KKILVSSLTQ
110 120 130 140 150
MTGNEPLLKN FYNVLLDNHR LYLLTRIQKQ FSTLMRAKRG EIEVKITSAT
160 170 180 190 200
PLDSKILSRL ESRIAKSKYG KGKLLVSNKV TPSIIGGLIV EIGDNILDVS
210
VGSRLNNLNK LLSEPI
Length:216
Mass (Da):23,988
Last modified:May 1, 2000 - v2
Checksum:i3E6C46129DF84074
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20129.2.
PIRiT41174.
RefSeqiNP_588505.1. NM_001023495.2.

Genome annotation databases

EnsemblFungiiSPCC1840.06.1; SPCC1840.06.1:pep; SPCC1840.06.
GeneIDi2539241.
KEGGispo:SPCC1840.06.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20129.2.
PIRiT41174.
RefSeqiNP_588505.1. NM_001023495.2.

3D structure databases

ProteinModelPortaliO74479.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275811. 1 interactor.
MINTiMINT-4679440.

Proteomic databases

MaxQBiO74479.
PRIDEiO74479.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC1840.06.1; SPCC1840.06.1:pep; SPCC1840.06.
GeneIDi2539241.
KEGGispo:SPCC1840.06.

Organism-specific databases

EuPathDBiFungiDB:SPCC1840.06.
PomBaseiSPCC1840.06. atp5.

Phylogenomic databases

HOGENOMiHOG000075825.
InParanoidiO74479.
KOiK02137.
OMAiMNPHVKR.
OrthoDBiEOG092C4VM2.
PhylomeDBiO74479.

Miscellaneous databases

PROiO74479.

Family and domain databases

Gene3Di1.10.520.20. 1 hit.
HAMAPiMF_01416. ATP_synth_delta_bact. 1 hit.
InterProiIPR026015. ATP_synth_OSCP/delta_N.
IPR000711. ATPase_OSCP/dsu.
[Graphical view]
PANTHERiPTHR11910. PTHR11910. 1 hit.
PfamiPF00213. OSCP. 1 hit.
[Graphical view]
PRINTSiPR00125. ATPASEDELTA.
SUPFAMiSSF47928. SSF47928. 1 hit.
TIGRFAMsiTIGR01145. ATP_synt_delta. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiATPO_SCHPO
AccessioniPrimary (citable) accession number: O74479
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2003
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.