O74478 (PGM2_SCHPO) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 64.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphoglucomutase-2 Short name=PGM 2 EC=5.4.2.2 Alternative name(s): Glucose phosphomutase 2 | ||
| Gene names |
| ||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ||
| Taxonomic identifier | 284812 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 587 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | This enzyme participates in both the breakdown and synthesis of glucose By similarity. |
| Catalytic activity | Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. |
| Cofactor | Binds 1 magnesium ion per subunit By similarity. |
| Subunit structure | Monomer By similarity. |
| Subcellular location | |
| Sequence similarities | Belongs to the phosphohexose mutase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Glucose metabolism |
| Cellular component | Cytoplasm Nucleus |
| Ligand | Magnesium Metal-binding |
| Molecular function | Isomerase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | glucose 1-phosphate metabolic process Inferred from sequence or structural similarity. Source: RefGenome |
| Cellular component | cytosol Inferred from direct assay. Source: GeneDB_Spombe nucleusInferred from direct assay. Source: GeneDB_Spombe |
| Molecular function | magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucomutase activityInferred from sequence or structural similarity. Source: GeneDB_Spombe |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 587 | 587 | Phosphoglucomutase-2 | PRO_0000315630 | |||||
Sites | |||||||||
| Active site | 149 | 1 | Phosphoserine intermediate By similarity | ||||||
| Metal binding | 149 | 1 | Magnesium; via phosphate group By similarity | ||||||
| Metal binding | 306 | 1 | Magnesium By similarity | ||||||
| Metal binding | 308 | 1 | Magnesium By similarity | ||||||
| Metal binding | 310 | 1 | Magnesium By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 149 | 1 | Phosphoserine Ref.3 | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CU329672 Genomic DNA. Translation: CAA20128.1. |
| PIR | T41173. |
| RefSeq | NP_588504.1. NM_001023494.1. |
3D structure databases | |
| ProteinModelPortal | O74478. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | O74478. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | SPCC1840.05c.1; SPCC1840.05c.1:pep; SPCC1840.05c. |
| GeneID | 2538920. |
| KEGG | spo:SPCC1840.05c. |
| NMPDR | fig|4896.1.peg.842. |
Organism-specific databases | |
| GeneDB_Spombe | SPCC1840.05c. |
Phylogenomic databases | |
| eggNOG | fuNOG05584. |
| GeneTree | EFGT00050000004521. |
| HOGENOM | HBG571743. |
| OMA | IYKEFGY. |
| OrthoDB | EOG4N605B. |
Gene expression databases | |
| ArrayExpress | O74478. |
Family and domain databases | |
| InterPro | IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. [Graphical view] |
| Gene3D | G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits. |
| KO | K01835. |
| Pfam | PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view] |
| PRINTS | PR00509. PGMPMM. |
| SUPFAM | SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits. |
| PROSITE | PS00710. PGM_PMM. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PGM2_SCHPO | ||||||||
| Accession | Primary (citable) accession number: O74478 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with