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Protein

N-terminal acetyltransferase B complex catalytic subunit naa20

Gene

naa20

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn, Met-Gln or Met-Met.By similarity

Catalytic activityi

Acetyl-CoA + an N-terminal L-methionyl-L-asparaginyl-[protein] = an N-terminal N(alpha)-acetyl-L-methionyl-L-asparginyl-[protein] + CoA.By similarity
Acetyl-CoA + an N-terminal L-methionyl-L-glutaminyl-[protein] = an N-terminal N(alpha)-acetyl-L-methionyl-L-glutaminyl-[protein] + CoA.By similarity
Acetyl-CoA + an N-terminal L-methionyl-L-aspartyl-[protein] = an N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] + CoA.By similarity
Acetyl-CoA + an N-terminal L-methionyl-L-glutamyl-[protein] = an N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] + CoA.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
N-terminal acetyltransferase B complex catalytic subunit naa20 (EC:2.3.1.254By similarity)
Short name:
NatB complex subunit naa20
Alternative name(s):
NatB Nalpha terminal acetyltransferase 3
Gene namesi
Name:naa20
Synonyms:nat3
ORF Names:SPCC16C4.12
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC16C4.12
PomBaseiSPCC16C4.12 naa20

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003102951 – 180N-terminal acetyltransferase B complex catalytic subunit naa20Add BLAST180

Proteomic databases

MaxQBiO74457
PaxDbiO74457
PRIDEiO74457

Interactioni

Subunit structurei

Component of the N-terminal acetyltransferase B (NatB) complex.By similarity

Protein-protein interaction databases

STRINGi4896.SPCC16C4.12.1

Structurei

3D structure databases

ProteinModelPortaliO74457
SMRiO74457
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 156N-acetyltransferasePROSITE-ProRule annotationAdd BLAST155

Sequence similaritiesi

Belongs to the acetyltransferase family.Curated

Phylogenomic databases

HOGENOMiHOG000078523
InParanoidiO74457
KOiK17972
OMAiWTETYGI
OrthoDBiEOG092C4MWD
PhylomeDBiO74457

Family and domain databases

InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR000182 GNAT_dom
PfamiView protein in Pfam
PF00583 Acetyltransf_1, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS51186 GNAT, 1 hit

Sequencei

Sequence statusi: Complete.

O74457-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDTRKFKAT DLFSFNNINL DPLTETFNIS FYLSYLNKWP SLCVVQESDL
60 70 80 90 100
SDPTLMGYIM GKSEGTGKEW HTHVTAITVA PNSRRLGLAR TMMDYLETVG
110 120 130 140 150
NSENAFFVDL FVRASNALAI DFYKGLGYSV YRRVIGYYSN PHGKDEDSFD
160 170 180
MRKPLSRDVN RESIRENGEN FKCSPADVSF
Length:180
Mass (Da):20,521
Last modified:November 1, 1998 - v1
Checksum:i6EAE4331AAEF10DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20751.1
PIRiT41102
RefSeqiNP_587922.1, NM_001022913.2

Genome annotation databases

EnsemblFungiiSPCC16C4.12.1; SPCC16C4.12.1:pep; SPCC16C4.12
GeneIDi2539279
KEGGispo:SPCC16C4.12

Similar proteinsi

Entry informationi

Entry nameiNAT3_SCHPO
AccessioniPrimary (citable) accession number: O74457
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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