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O74455

- 6PGL_SCHPO

UniProt

O74455 - 6PGL_SCHPO

Protein

Probable 6-phosphogluconolactonase

Gene

SPCC16C4.10

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.By similarity

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: PomBase

    GO - Biological processi

    1. pentose-phosphate shunt, oxidative branch Source: PomBase

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    ReactomeiREACT_212835. Pentose phosphate pathway (hexose monophosphate shunt).
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable 6-phosphogluconolactonase (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    ORF Names:SPCC16C4.10
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome III

    Organism-specific databases

    PomBaseiSPCC16C4.10.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: PomBase
    2. nucleus Source: PomBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 257257Probable 6-phosphogluconolactonasePRO_0000090086Add
    BLAST

    Proteomic databases

    MaxQBiO74455.
    PaxDbiO74455.

    Interactioni

    Protein-protein interaction databases

    BioGridi275499. 179 interactions.
    MINTiMINT-4679205.
    STRINGi4896.SPCC16C4.10-1.

    Structurei

    3D structure databases

    ProteinModelPortaliO74455.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    HOGENOMiHOG000256285.
    KOiK01057.
    OMAiTYGLYKS.
    OrthoDBiEOG7MD51D.
    PhylomeDBiO74455.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O74455-1 [UniParc]FASTAAdd to Basket

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    MSVYSFSDVS LVAKALGAFV KEKSEASIKR HGVFTLALSG GSLPKVLAEG    50
    LAQQRGIEFS KWEVFFADER IVPLDDENSN YALCKKLIFD KFEGFDPKKI 100
    HTINPELLKE NPIDPQNVAD EYEKQLVHVF ANSSTVKVPV FDLLLLGCGP 150
    DGHTCSLFPD HEVLQEDVAW VAPVTDSPKP PKDRITLTLP VVTHAQAIAF 200
    VTTGAGKKDI LPIVIEDFTS KLPSALITRN NLTRTSWFVD DEASANLERS 250
    SLKVFPQ 257
    Length:257
    Mass (Da):28,351
    Last modified:November 1, 1998 - v1
    Checksum:iBCA71AB0BA7086DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329672 Genomic DNA. Translation: CAA20749.1.
    PIRiT41100.
    RefSeqiNP_587920.1. NM_001022911.2.

    Genome annotation databases

    EnsemblFungiiSPCC16C4.10.1; SPCC16C4.10.1:pep; SPCC16C4.10.
    GeneIDi2538922.
    KEGGispo:SPCC16C4.10.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329672 Genomic DNA. Translation: CAA20749.1 .
    PIRi T41100.
    RefSeqi NP_587920.1. NM_001022911.2.

    3D structure databases

    ProteinModelPortali O74455.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 275499. 179 interactions.
    MINTi MINT-4679205.
    STRINGi 4896.SPCC16C4.10-1.

    Proteomic databases

    MaxQBi O74455.
    PaxDbi O74455.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPCC16C4.10.1 ; SPCC16C4.10.1:pep ; SPCC16C4.10 .
    GeneIDi 2538922.
    KEGGi spo:SPCC16C4.10.

    Organism-specific databases

    PomBasei SPCC16C4.10.

    Phylogenomic databases

    eggNOGi COG0363.
    HOGENOMi HOG000256285.
    KOi K01057.
    OMAi TYGLYKS.
    OrthoDBi EOG7MD51D.
    PhylomeDBi O74455.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    Reactomei REACT_212835. Pentose phosphate pathway (hexose monophosphate shunt).

    Miscellaneous databases

    NextBioi 20800100.
    PROi O74455.

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry namei6PGL_SCHPO
    AccessioniPrimary (citable) accession number: O74455
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3