Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable cation-transporting ATPase C1672.11c

Gene

SPCC1672.11c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei619 – 61914-aspartylphosphate intermediateBy similarity
Metal bindingi1015 – 10151MagnesiumBy similarity
Metal bindingi1019 – 10191MagnesiumBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-936837. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cation-transporting ATPase C1672.11c (EC:3.6.3.-)
Gene namesi
ORF Names:SPCC1672.11c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1672.11c.
PomBaseiSPCC1672.11c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 139139CytoplasmicSequence analysisAdd
BLAST
Transmembranei140 – 16122HelicalSequence analysisAdd
BLAST
Topological domaini162 – 1676ExtracellularSequence analysis
Transmembranei168 – 19023HelicalSequence analysisAdd
BLAST
Topological domaini191 – 324134CytoplasmicSequence analysisAdd
BLAST
Transmembranei325 – 34723HelicalSequence analysisAdd
BLAST
Topological domaini348 – 3503ExtracellularSequence analysis
Transmembranei351 – 36919HelicalSequence analysisAdd
BLAST
Topological domaini370 – 531162CytoplasmicSequence analysisAdd
BLAST
Transmembranei532 – 55120HelicalSequence analysisAdd
BLAST
Topological domaini552 – 56413ExtracellularSequence analysisAdd
BLAST
Transmembranei565 – 58622HelicalSequence analysisAdd
BLAST
Topological domaini587 – 1072486CytoplasmicSequence analysisAdd
BLAST
Transmembranei1073 – 109119HelicalSequence analysisAdd
BLAST
Topological domaini1092 – 10998ExtracellularSequence analysis
Transmembranei1100 – 111718HelicalSequence analysisAdd
BLAST
Topological domaini1118 – 113518CytoplasmicSequence analysisAdd
BLAST
Transmembranei1136 – 115924HelicalSequence analysisAdd
BLAST
Topological domaini1160 – 118021ExtracellularSequence analysisAdd
BLAST
Transmembranei1181 – 120323HelicalSequence analysisAdd
BLAST
Topological domaini1204 – 121613CytoplasmicSequence analysisAdd
BLAST
Transmembranei1217 – 123620HelicalSequence analysisAdd
BLAST
Topological domaini1237 – 125317ExtracellularSequence analysisAdd
BLAST
Transmembranei1254 – 127421HelicalSequence analysisAdd
BLAST
Topological domaini1275 – 131541CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • endoplasmic reticulum Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13151315Probable cation-transporting ATPase C1672.11cPRO_0000046352Add
BLAST

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO74431.

Interactioni

Protein-protein interaction databases

BioGridi275332. 1 interaction.
MINTiMINT-4678988.

Structurei

3D structure databases

ProteinModelPortaliO74431.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000171813.
InParanoidiO74431.
KOiK14951.
OMAiKVMRSGL.
OrthoDBiEOG74R1ZZ.
PhylomeDBiO74431.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 2 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006544. P-type_TPase_V.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 2 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 3 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74431-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPKMIRSK RSTSSIASKN SLNSYLASSL MSHDSIFDGP GLGTSIPSSV
60 70 80 90 100
SSFHHQTLRP SSDASVSQFS MDYLQSEYNL NRYNDGESIA ASRDYQSLLR
110 120 130 140 150
DNGSGVYSDE EEITEMMLEE LNIHPVLRRE SVGEAAGLSE DGCCQILYLV
160 170 180 190 200
EEDLEVGIAG YKTNKSRYRL YQAICLLTLG LAYLIFRWLP KYFIRFVGTR
210 220 230 240 250
EPLATADWLT IETQWGELSK LDIQIQPYEN SLSSIFGASI RVAAPEGTEN
260 270 280 290 300
DPFIENFRYV NYRYMKLIFH PLLDRFLIQQ DWKDPRWIRD TSVVKEGLER
310 320 330 340 350
DAINDRLCIF GENLIDLELK SVSQLLIDEV LHPFYIFQVF SIILWSMDSY
360 370 380 390 400
YYYAICILII SVVSILGSLI ETRKTLRRMR EMSRFTCPVR VYRDGFWTSI
410 420 430 440 450
SSTDLVIGDV FEISDPELTI FPADALLLSG DCIVNESMLT GESIPVSKIP
460 470 480 490 500
ATDQSMKELF SFSKNIPASL CKHFLFSGTK IIQVRKPFVN EKEEGASLAM
510 520 530 540 550
VVRTGFNTTK GALVRSMIFP KPTNFSFYRD SFRFITAMFI IALIGFVFSS
560 570 580 590 600
INLLTLGVPI ATIIIRALDL ITIVVPPALP ATLTIGTTFA ISRLRKQGIF
610 620 630 640 650
CISPQRVNVS GKLDLISFDK TGTLTEDGLD IMGVSVIEGS ELGDLRSNSG
660 670 680 690 700
NLCSKDLLSN DSPSNLLYTM ATCHMLRYVD GELVGDPLDI KMFKFTHWSY
710 720 730 740 750
SEENFLNKKM SSEQAEDAAY VRTQQLIPPT VSPPWNSPSN NYTESDLELG
760 770 780 790 800
IVRTFEFVSQ LRRMAVIVKH GKFKKMDAYV KGAPEIMPSI CKPESFPANY
810 820 830 840 850
QEVLDYYTHN GFRVIACASK QLENCTWAKA QRMKREQVEC DLDFCGFIVF
860 870 880 890 900
ENKLKSTTAT VIRELNDARI RTVMCTGDNV LTSICVGKRC GMLPEDGYVF
910 920 930 940 950
LPRFDEESES ADEASRQLVW QAIENNEIFL DPHTLRPNVD FADHEPVSIE
960 970 980 990 1000
LARLKDFHIA LTGDVFRWLV DYAPLNVFHH ILLKAQIFAR MSPSEKNELV
1010 1020 1030 1040 1050
SCFQNLNYCV GFCGDGANDC GALKAADVGI SLSEAEASVA APFTSKWFEI
1060 1070 1080 1090 1100
TCVLDVIKDG RAALVTSFSC FQYMALYSAI QFITVSILYT TNSNLGDFQF
1110 1120 1130 1140 1150
LFIDLVIILP IAVFMGRSRP YHRLAHKRPT ANLVSKRILS PLIGQIVLIC
1160 1170 1180 1190 1200
IIQYITLRIV RREPWYIPPP ANSSDTNITN SDVTALFLIS CFQYIFIGVV
1210 1220 1230 1240 1250
LSIGPPYREK VWRNYSFTAV VVVLLILTVK LIRLQNHKNF FMKLFQLTPT
1260 1270 1280 1290 1300
SKSFQNFLIF AGVIYYLLAA SGQNYIFISM TNFISHLNNR LLNRRTKVSK
1310
KLYKRLFADL QNEQV
Length:1,315
Mass (Da):148,787
Last modified:November 1, 1998 - v1
Checksum:i081A550E59F2B0B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20449.1.
PIRiT41055.
RefSeqiNP_587882.1. NM_001022874.2.

Genome annotation databases

EnsemblFungiiSPCC1672.11c.1; SPCC1672.11c.1:pep; SPCC1672.11c.
GeneIDi2538749.
KEGGispo:SPCC1672.11c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20449.1.
PIRiT41055.
RefSeqiNP_587882.1. NM_001022874.2.

3D structure databases

ProteinModelPortaliO74431.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275332. 1 interaction.
MINTiMINT-4678988.

Proteomic databases

MaxQBiO74431.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC1672.11c.1; SPCC1672.11c.1:pep; SPCC1672.11c.
GeneIDi2538749.
KEGGispo:SPCC1672.11c.

Organism-specific databases

EuPathDBiFungiDB:SPCC1672.11c.
PomBaseiSPCC1672.11c.

Phylogenomic databases

HOGENOMiHOG000171813.
InParanoidiO74431.
KOiK14951.
OMAiKVMRSGL.
OrthoDBiEOG74R1ZZ.
PhylomeDBiO74431.

Enzyme and pathway databases

ReactomeiR-SPO-936837. Ion transport by P-type ATPases.

Miscellaneous databases

PROiO74431.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 2 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006544. P-type_TPase_V.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 2 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 3 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiATC9_SCHPO
AccessioniPrimary (citable) accession number: O74431
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: June 8, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.