Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable lipase C1672.09

Gene

SPCC1672.09

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable lipase.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei222NucleophileBy similarity1
Active sitei389Charge relay systemBy similarity1
Active sitei415Charge relay systemBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

Enzyme and pathway databases

ReactomeiR-SPO-192456 Digestion of dietary lipid
R-SPO-6809371 Formation of the cornified envelope

Protein family/group databases

ESTHERischpo-SPCC1672.09 Acidic_Lipase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lipase C1672.09 (EC:3.1.1.-)
Gene namesi
ORF Names:SPCC1672.09
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1672.09
PomBaseiSPCC1672.09

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 17CytoplasmicSequence analysisAdd BLAST17
Transmembranei18 – 38Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini39 – 467LumenalSequence analysisAdd BLAST429

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003126591 – 467Probable lipase C1672.09Add BLAST467

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei66Phosphoserine1 Publication1
Glycosylationi311N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi316N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiO74430
PaxDbiO74430
PRIDEiO74430

PTM databases

iPTMnetiO74430

Interactioni

Protein-protein interaction databases

BioGridi275910, 10 interactors
STRINGi4896.SPCC1672.09.1

Structurei

3D structure databases

ProteinModelPortaliO74430
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 421AB hydrolase-1Sequence analysisAdd BLAST295

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000173756
InParanoidiO74430
KOiK01052
OMAiACWMLLL
OrthoDBiEOG092C1FMW
PhylomeDBiO74430

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

O74430-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQLPFIQRL KWEEYMALFL GFFFVIFEKL LSCLAFMIHN TLGLFYRSVV
60 70 80 90 100
RNEIKKRSKK RSRSRSVSLQ RAKAIHDAAD IREMCKISGY YVEDHLVRTE
110 120 130 140 150
DDYILCIHRI SKDSPGRIGS PHPKKLPVVY CHHGLLMNSE VWVCNVDPRN
160 170 180 190 200
CLVFDLVNKG YDVWLGNNRG NKYSRQHLRF DSTDKEFWDF SIDDFAQYDI
210 220 230 240 250
PDTIDYILKT SGQTKLTYIG FSQGTAQAFA SLSIHPLLND KINSLIALAP
260 270 280 290 300
AISPKGLHNR VVDAFVKARP SILFFLFGRK SILPSAGFWQ SFLAPKFFDA
310 320 330 340 350
VLAYCLSQLF NWSCQNISSY QRLVSFAHLY SYTSVKCLVH WFQIMRSAEF
360 370 380 390 400
RMYDNDQLGH DYFLKYYKAA KFPTNNIRTP IYLIWGGSDS LVDIQAMLNA
410 420 430 440 450
LPAEVEHVKV DSYEHLDMIW ADTVKDYVIP PVLRRLRDIH HPPEHEENDK
460
ENREIQKNHI APRNKPI
Length:467
Mass (Da):54,381
Last modified:November 1, 1998 - v1
Checksum:i2ED7D0A3F5D86FEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20447.1
PIRiT41053
RefSeqiNP_587880.1, NM_001022872.2

Genome annotation databases

EnsemblFungiiSPCC1672.09.1; SPCC1672.09.1:pep; SPCC1672.09
GeneIDi2539344
KEGGispo:SPCC1672.09

Similar proteinsi

Entry informationi

Entry nameiTGCE1_SCHPO
AccessioniPrimary (citable) accession number: O74430
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health