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Protein

Nucleoporin nup211

Gene

nup211

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.1 Publication

GO - Molecular functioni

GO - Biological processi

  • mitotic spindle assembly checkpoint Source: GO_Central
  • mRNA export from nucleus Source: PomBase
  • protein import into nucleus Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoporin nup211
Alternative name(s):
Nuclear pore protein nup211
Gene namesi
Name:nup211
ORF Names:SPCC162.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC162.08c.
PomBaseiSPCC162.08c. nup211.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • nuclear periphery Source: PomBase
  • nuclear pore Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002906731 – 1837Nucleoporin nup211Add BLAST1837

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei650Phosphothreonine1 Publication1
Modified residuei1558Phosphoserine1 Publication1
Modified residuei1560Phosphothreonine1 Publication1
Modified residuei1563Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO74424.
PRIDEiO74424.

PTM databases

iPTMnetiO74424.

Interactioni

Protein-protein interaction databases

BioGridi275424. 20 interactors.
IntActiO74424. 1 interactor.
MINTiMINT-4678924.

Structurei

3D structure databases

ProteinModelPortaliO74424.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili59 – 378Sequence analysisAdd BLAST320
Coiled coili415 – 519Sequence analysisAdd BLAST105
Coiled coili559 – 625Sequence analysisAdd BLAST67
Coiled coili661 – 1163Sequence analysisAdd BLAST503
Coiled coili1222 – 1637Sequence analysisAdd BLAST416
Coiled coili1675 – 1712Sequence analysisAdd BLAST38

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoidiO74424.
KOiK09291.
OMAiCASLGHA.
OrthoDBiEOG092C0471.
PhylomeDBiO74424.

Family and domain databases

InterProiIPR012929. TPR/MLP1.
[Graphical view]
PfamiPF07926. TPR_MLP1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74424-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHDSSWTEAD ILGVCSFLDI PKTKIDPLLQ VDAFTSILIP LISKSKDYES
60 70 80 90 100
IKNDRIVTEV NYEQQLRNSE KKLLQSNERY DLLEDERKLL ENELSQIKEY
110 120 130 140 150
LREKSSSYDT VLHDCSSLKS VNEALKQAQD QNLKQTAQLQ NLLSDKEKEV
160 170 180 190 200
EKKITIIKDL KDALASSTHQ VLELQHTQQE KASLQTNYEF ELQKLTQKNS
210 220 230 240 250
ILENNNTWLS RELQGVNDKL LSLHQEASLE KSQLSSQLSD AVLEKDALQR
260 270 280 290 300
KVSSLSQQFT ESNLRYQNIV AELSEMRKQY EFSQVSFEKE ISSQKQISEL
310 320 330 340 350
WMEKCEDCSL RLKELQNSNG ELEKLLEAAQ SSFEEQLESH KEAEASLKSQ
360 370 380 390 400
INFLEKEVSS LESQLKLANE RLRHYDEIEI SDMSELKYSN LLNNSMKGFK
410 420 430 440 450
GQSSVSDLYS ERLYYKQKYE QTCQEVERLQ RSYNHVMEEA NLQHPLVKEQ
460 470 480 490 500
FKRFAHMQRE IVAMSEQYQK SLEDCQKAKS RYEQLETLFK DKCTENKHYE
510 520 530 540 550
QETKDLARQV QVLLHELDLC ENGIVLGVDS RKKINSYVEK SLTEDETDTD
560 570 580 590 600
QIISSRLVVF RNIRELQQQN QNLLSAVHEL ADRMEKDEKP DLDGAEIQEE
610 620 630 640 650
TLIKANETID QLTKMLEEVS DQLRYSLKER DFFRSLVQEN EKLLDMAPAT
660 670 680 690 700
PNSKLNTNLI EQTSYQRSLI RLEQLTNELE SLKSISRNKE KKFEEAISSL
710 720 730 740 750
QLEKSNIQLQ LTSLTSERSL ALEKLNDLEK SLVLSERSKD ELDESYKSLQ
760 770 780 790 800
EQLASKKIEV QNVSSQLSIC NSQLEQSNHI VDNLKSENLL LTSVKDKLKA
810 820 830 840 850
DLSNLESKLS SLQQDNFHMK AQIESSNQEY TATVDSMNSR ILELSNDLRV
860 870 880 890 900
ANSKLSECSD DVRRLTLQNS FDLREHQTLV LQLQSNITEL KQDITLQRTV
910 920 930 940 950
RNQLEIQTTE LKERLKFMEE RQENLQSKLI AANKDTTQNP DNVEVEAISI
960 970 980 990 1000
ELERTKEKLR MAELEKSNIQ QKYLASEKTL EMMNETHEQF KHLVESEIST
1010 1020 1030 1040 1050
REEKITSLRS ELLDLNKRVE VLKEEKESSS KELAKQLEDA VREKDSALSF
1060 1070 1080 1090 1100
KKDYEKIRSD ADRVITSLKE DIEKERSLMK ECHSNYESEI VSHGRTTQKL
1110 1120 1130 1140 1150
RDLRTEFDEV NTKYLKLKAN FEQQHSGLSG AEKDWNIQRK AMEDEISSLK
1160 1170 1180 1190 1200
DYILGLENQN KLLHSQFDSL SQQITVLQQN SSENLNISAN LEAVQDNDLR
1210 1220 1230 1240 1250
ELVSYLRHEK EIMDNKYELT ILDNRGLNQQ VKSLQSTVDS LQLELNRLQS
1260 1270 1280 1290 1300
LPVSNDQTDT PIISGSQEVQ LLYESNSVLR KDNDAKLGKI QELEKEVEKL
1310 1320 1330 1340 1350
NASLNPLQTE INELKAEIGA KTASLNLMKE YNSRWKLRFQ SVLNKYERVD
1360 1370 1380 1390 1400
PTQLEELKKN CEALEKEKQE LETKLQETAK ETDTFKQQVN SLNEEVENLK
1410 1420 1430 1440 1450
KEVEQANTKN TRLAAAWNEK CENLKKSSLT RFAHLKQELT NKNKELTSKN
1460 1470 1480 1490 1500
AENEAMQKEI ESLKDSNHQL QESASSDAEQ ITKEQFEQLK SEKERTEKEL
1510 1520 1530 1540 1550
ADSKNELEHL QSEAVDADGK TEISNLEKEI HELRSDKEGL VQQVQNLSAE
1560 1570 1580 1590 1600
LAALREHSPT QGSLENADEI ARLRSQLEST KQYYEKEKET EILAARSELV
1610 1620 1630 1640 1650
AEKEKTKEEL ENQLNEKSQR IKELEEQAQK NSSENTHDNI DDMIKQQVEE
1660 1670 1680 1690 1700
KLKENSANFD VKLKKVVAET EFRSKAKISV YEKKTRDLQN KITQLEETIE
1710 1720 1730 1740 1750
NLNKQLSNPE KTDESTSSVT ETKPVTSKPT ASKADVGQNA TEASSAKREP
1760 1770 1780 1790 1800
SGKSLSARLQ GTGKQKGVQR PAVSRPVPMK PDSGKLSITG ASKRIATSKN
1810 1820 1830
AAQNAKELSS TAKSGSLKRQ RDDANKGGSS SNQKKAK
Length:1,837
Mass (Da):211,459
Last modified:November 1, 1998 - v1
Checksum:i1574A467D781E442
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA19588.1.
PIRiT41023.
RefSeqiNP_588236.1. NM_001023226.2.

Genome annotation databases

EnsemblFungiiSPCC162.08c.1; SPCC162.08c.1:pep; SPCC162.08c.
GeneIDi2538843.
KEGGispo:SPCC162.08c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA19588.1.
PIRiT41023.
RefSeqiNP_588236.1. NM_001023226.2.

3D structure databases

ProteinModelPortaliO74424.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275424. 20 interactors.
IntActiO74424. 1 interactor.
MINTiMINT-4678924.

PTM databases

iPTMnetiO74424.

Proteomic databases

MaxQBiO74424.
PRIDEiO74424.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC162.08c.1; SPCC162.08c.1:pep; SPCC162.08c.
GeneIDi2538843.
KEGGispo:SPCC162.08c.

Organism-specific databases

EuPathDBiFungiDB:SPCC162.08c.
PomBaseiSPCC162.08c. nup211.

Phylogenomic databases

InParanoidiO74424.
KOiK09291.
OMAiCASLGHA.
OrthoDBiEOG092C0471.
PhylomeDBiO74424.

Miscellaneous databases

PROiO74424.

Family and domain databases

InterProiIPR012929. TPR/MLP1.
[Graphical view]
PfamiPF07926. TPR_MLP1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNU211_SCHPO
AccessioniPrimary (citable) accession number: O74424
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.