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Protein

Vacuolar protein sorting-associated protein 9a

Gene

vps901

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Required for vacuolar protein sorting; may be required for the consumption of transport vesicles containing vacuolar protein precursors.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 9a
Alternative name(s):
Vacuolar protein-targeting protein 9a
Gene namesi
Name:vps901
Synonyms:vps9a
ORF Names:SPBC4F6.10
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC4F6.10.
PomBaseiSPBC4F6.10. vps901.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 572572Vacuolar protein sorting-associated protein 9aPRO_0000316571Add
BLAST

Proteomic databases

MaxQBiO74396.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini219 – 357139VPS9PROSITE-ProRule annotationAdd
BLAST
Domaini529 – 57143CUEPROSITE-ProRule annotationAdd
BLAST

Domaini

The CUE domain (Coupling of ubiquitin conjugation to ER degradation) is monoubiquitin-binding and is required for intramolecular ubiquitination.By similarity

Sequence similaritiesi

Contains 1 CUE domain.PROSITE-ProRule annotation
Contains 1 VPS9 domain.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiO74396.
OrthoDBiEOG7MPRRD.

Family and domain databases

InterProiIPR003892. CUE.
IPR009060. UBA-like.
IPR003123. VPS9.
[Graphical view]
PfamiPF02845. CUE. 1 hit.
PF02204. VPS9. 1 hit.
[Graphical view]
SMARTiSM00546. CUE. 1 hit.
SM00167. VPS9. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
PROSITEiPS51140. CUE. 1 hit.
PS51205. VPS9. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74396-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYPSFHEDP TKDESTVAEQ RKGQSNEEKP LIDLNDSLDE QRNAYNEHCK
60 70 80 90 100
NHDQQPSQQV RNMEDEANQY EQTDSSSDQE VMNEKQSLDK ENRNDNIPHE
110 120 130 140 150
NNPGQQEINE PIFDFHMFLE QLRSSSAEPV AKYLKSFLSE FTKRRWTVNY
160 170 180 190 200
QVKLIRDFLK FINEKIEQYE PWASGSQAEI DNAKEGMEKL VLNRLYTSLF
210 220 230 240 250
SPEIAKSGIP LSSEHSDDVE EDRVLSEKME LFQWITEENL DIKKQKSSSK
260 270 280 290 300
FFKLAADELR RINDYHAPRD KIICLLNCCK VIFSYLRNVV KEESADMFVP
310 320 330 340 350
ILIFVVLQAR PAHLVSNIQY IQRFRSPEKL TGEVMYYLST LMGAMSFIET
360 370 380 390 400
LDCSSLTITE EEFNAQIEKS IKKMEERKLS EKSESKTAVN ENATYKDPVL
410 420 430 440 450
SRGLSSSIDV STGVALVNLP EELENMKYLQ IDTPESKEYP RSTRPRASSH
460 470 480 490 500
SGSFTTDSGK RSRRNSNKYV GSSDRPPYRV SRAYSSSATH SPIVHEEQPV
510 520 530 540 550
DDGLQQNDDL REATTASLET AEAERLQARE KAEAITALRA MFPAFDSEVI
560 570
EVVLNAQQGR LSSSIDSLLE MS
Length:572
Mass (Da):65,554
Last modified:March 21, 2012 - v3
Checksum:i1F617712EF331CF1
GO

Sequence cautioni

The sequence CAA20730.2 differs from that shown. Reason: Frameshift at position 447. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ665299 mRNA. Translation: ABG66956.1.
CU329671 Genomic DNA. Translation: CAA20730.2. Frameshift.
PIRiT40507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ665299 mRNA. Translation: ABG66956.1.
CU329671 Genomic DNA. Translation: CAA20730.2. Frameshift.
PIRiT40507.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiO74396.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

EuPathDBiFungiDB:SPBC4F6.10.
PomBaseiSPBC4F6.10. vps901.

Phylogenomic databases

InParanoidiO74396.
OrthoDBiEOG7MPRRD.

Miscellaneous databases

PROiO74396.

Family and domain databases

InterProiIPR003892. CUE.
IPR009060. UBA-like.
IPR003123. VPS9.
[Graphical view]
PfamiPF02845. CUE. 1 hit.
PF02204. VPS9. 1 hit.
[Graphical view]
SMARTiSM00546. CUE. 1 hit.
SM00167. VPS9. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
PROSITEiPS51140. CUE. 1 hit.
PS51205. VPS9. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Schizosaccharomyces pombe Vps9 protein mRNA, complete cds."
    Miyamoto M., Saito N., Matsuda T.
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  3. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF FRAMESHIFT.
    Strain: 972 / ATCC 24843 and JY3.
  4. "Augmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability."
    Bitton D.A., Wood V., Scutt P.J., Grallert A., Yates T., Smith D.L., Hagan I.M., Miller C.J.
    Genetics 187:1207-1217(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVISION OF GENE MODEL, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiVPS91_SCHPO
AccessioniPrimary (citable) accession number: O74396
Secondary accession number(s): D2CFN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 21, 2012
Last modified: June 8, 2016
This is version 81 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.