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Protein

Protein sof1

Gene

sof1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for ribosomal RNA processing.By similarity

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SPO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-SPO-8951664 Neddylation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein sof1
Alternative name(s):
U3 small nucleolar RNA-associated protein sof1
Short name:
U3 snoRNA-associated protein sof1
Gene namesi
Name:sof1
ORF Names:SPBC1A4.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1A4.07c
PomBaseiSPBC1A4.07c sof1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003165451 – 436Protein sof1Add BLAST436

Proteomic databases

MaxQBiO74340
PaxDbiO74340
PRIDEiO74340

Interactioni

Subunit structurei

Interacts with snoRNA U3. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3 (By similarity).By similarity

Protein-protein interaction databases

BioGridi277315, 4 interactors
STRINGi4896.SPBC1A4.07c.1

Structurei

3D structure databases

ProteinModelPortaliO74340
SMRiO74340
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati62 – 102WD 1Add BLAST41
Repeati105 – 143WD 2Add BLAST39
Repeati145 – 175WD 3Add BLAST31
Repeati176 – 225WD 4Add BLAST50
Repeati227 – 267WD 5Add BLAST41
Repeati271 – 310WD 6Add BLAST40
Repeati314 – 353WD 7Add BLAST40

Sequence similaritiesi

Belongs to the WD repeat DCAF13/WDSOF1 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000210082
InParanoidiO74340
KOiK11806
OMAiVMDVEFS
OrthoDBiEOG092C20W2
PhylomeDBiO74340

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR011047 Quinoprotein_ADH-like_supfam
IPR007287 Sof1
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
PfamiView protein in Pfam
PF04158 Sof1, 1 hit
PF00400 WD40, 3 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50998 SSF50998, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O74340-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVKTITRGT SLTRLNDQDP VKRNLDPSLH PFERAREYTR ALNATKMDRM
60 70 80 90 100
FAAPFLGQLG RGHQDGVYSL ARDTKTLIDC ASGSGDGAVK LWDASERCER
110 120 130 140 150
WTSKAHEGIV RGLVFSNQGD VLSCASDRYV YMLNKQDGKV KRSYLGDSSL
160 170 180 190 200
LDIDTSKGGD LFATSGENVS IWDYSRDTPV TKFEWGADTL PVVKFNYTET
210 220 230 240 250
SVLASAGMDR SIVIYDLRTS SPLTKLITKL RTNSISWNPM EAFNFVAGSE
260 270 280 290 300
DHNLYMYDMR NLKRALHVYK DHVSAVMSVD FSPTGQEFVS GSYDKTIRIY
310 320 330 340 350
NVREGHSRDV YHTKRMQRVT AVKFSMDAQY IFSGSDDSNV RLWRARASSR
360 370 380 390 400
ASIRSTREEN RLKYLDSLRE RYKHIPEIRR IARHRHLPTN VKKAAEIKRE
410 420 430
EINSLKRREE NIRRHSKKGA VPYEKERERH VVGIQK
Length:436
Mass (Da):49,995
Last modified:November 1, 1998 - v1
Checksum:i4846F514D2863510
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA20111.1
PIRiT39855
RefSeqiNP_595809.1, NM_001021712.2

Genome annotation databases

EnsemblFungiiSPBC1A4.07c.1; SPBC1A4.07c.1:pep; SPBC1A4.07c
GeneIDi2540796
KEGGispo:SPBC1A4.07c

Similar proteinsi

Entry informationi

Entry nameiDCA13_SCHPO
AccessioniPrimary (citable) accession number: O74340
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 1, 1998
Last modified: June 20, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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