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O74326 (CID11_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) RNA polymerase cid11

Short name=PAP
EC=2.7.7.19
Alternative name(s):
Caffeine-induced death protein 11
Polynucleotide adenylyltransferase cid11
Gene names
Name:cid11
ORF Names:SPBC1685.06
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length478 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Cofactor

Magnesium or manganese By similarity.

Subcellular location

Cytoplasm. Nucleus Ref.2.

Sequence similarities

Belongs to the DNA polymerase type-B-like family.

Contains 1 PAP-associated domain.

Ontologies

Keywords
   Biological processmRNA processing
   Cellular componentCytoplasm
Nucleus
   LigandATP-binding
Magnesium
Manganese
Metal-binding
Nucleotide-binding
RNA-binding
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytosol

Inferred from direct assay Ref.2. Source: PomBase

nucleus

Inferred from direct assay Ref.2. Source: PomBase

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

RNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

polynucleotide adenylyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 478478Poly(A) RNA polymerase cid11
PRO_0000256154

Regions

Domain263 – 31755PAP-associated

Sites

Metal binding1061Magnesium or manganese; catalytic By similarity
Metal binding1081Magnesium or manganese; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
O74326 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 5D769C049DCC0CF0

FASTA47854,543
        10         20         30         40         50         60 
MELLTFTCCP FEGQMQQKKR RFDANLVQLQ ESEHRNDQIN ETVDAELTNE CWKLYMRLKP 

        70         80         90        100        110        120 
SNEEVSRRQQ FVDKLRTILS TEIKDAKLDL FVFGSTENNL AIQQSDVDVC IITNGSKYLN 

       130        140        150        160        170        180 
STCQLAQLLY SYGMKQIVCV SRARVPIVKI WDPQFDIHCD LNINNDVAKI NTKMLRLFVS 

       190        200        210        220        230        240 
IDPRVRPLGL IIKYWAKQRA LCDAAGSGTI TSYTISCMLV NFLQTRNPPI LPAMLDLMSN 

       250        260        270        280        290        300 
DDNKMFVDDI VGFKEKATLN KTSLGRLLID FFYYYGFSFN YLDSVVSVRS GTVLNKQEKG 

       310        320        330        340        350        360 
WAMEVNNSLC VEEPFNTARN LANTADNPSV KGLQSEFQRA FRLMSENNAC ERLCKICEEY 

       370        380        390        400        410        420 
QFLDITNEAN YGNTNTPFNT AYESFGCNHT VLPEAAAYPK PYYPPQITLS DGGNMNFLYY 

       430        440        450        460        470 
IPDESNHQSY ENKANRDSDF QGQTSLTQGS APPWHYIPCQ SWLVWYPSED ASNPASGN 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAA20054.1.
PIRT39522.
RefSeqNP_595210.1. NM_001021117.2.

3D structure databases

ProteinModelPortalO74326.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-4678261.
STRING4896.SPBC1685.06-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC1685.06.1; SPBC1685.06.1:pep; SPBC1685.06.
GeneID2539762.
KEGGspo:SPBC1685.06.

Organism-specific databases

PomBaseSPBC1685.06.

Phylogenomic databases

eggNOGCOG5260.
KOK13291.
OMASWDKQVI.
OrthoDBEOG72C580.
PhylomeDBO74326.

Family and domain databases

InterProIPR002934. Nucleotidyltransferase.
IPR002058. PAP_assoc.
[Graphical view]
PfamPF01909. NTP_transf_2. 1 hit.
PF03828. PAP_assoc. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20800912.

Entry information

Entry nameCID11_SCHPO
AccessionPrimary (citable) accession number: O74326
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 1, 1998
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names