O74326 (CID11_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Poly(A) RNA polymerase cid11
Short name=PAP
EC=2.7.7.19

Alternative name(s):
Caffeine-induced death protein 11
Polynucleotide adenylyltransferase cid11

Gene names

Name:	cid11
ORF Names:	SPBC1685.06

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	478 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + RNA(n) = diphosphate + RNA(n+1).
Cofactor	Magnesium or manganese By similarity.
Subcellular location	Cytoplasm. Nucleus Ref.2.
Sequence similarities	Belongs to the DNA polymerase type-B-like family. Contains 1 PAP-associated domain.

Ontologies

Keywords
Biological process	mRNA processing
Cellular component	Cytoplasm Nucleus
Ligand	ATP-binding Magnesium Manganese Metal-binding Nucleotide-binding RNA-binding
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytosol Inferred from direct assay Ref.2. Source: PomBase nucleus Inferred from direct assay Ref.2. Source: PomBase
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW polynucleotide adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 478	478	Poly(A) RNA polymerase cid11		PRO_0000256154
Regions
	Domain	263 – 317	55	PAP-associated
Sites
	Metal binding	106	1	Magnesium or manganese; catalytic By similarity
	Metal binding	108	1	Magnesium or manganese; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	O74326 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 5D769C049DCC0CF0	FASTA	478	54,543
	10 20 30 40 50 60 MELLTFTCCP FEGQMQQKKR RFDANLVQLQ ESEHRNDQIN ETVDAELTNE CWKLYMRLKP 70 80 90 100 110 120 SNEEVSRRQQ FVDKLRTILS TEIKDAKLDL FVFGSTENNL AIQQSDVDVC IITNGSKYLN 130 140 150 160 170 180 STCQLAQLLY SYGMKQIVCV SRARVPIVKI WDPQFDIHCD LNINNDVAKI NTKMLRLFVS 190 200 210 220 230 240 IDPRVRPLGL IIKYWAKQRA LCDAAGSGTI TSYTISCMLV NFLQTRNPPI LPAMLDLMSN 250 260 270 280 290 300 DDNKMFVDDI VGFKEKATLN KTSLGRLLID FFYYYGFSFN YLDSVVSVRS GTVLNKQEKG 310 320 330 340 350 360 WAMEVNNSLC VEEPFNTARN LANTADNPSV KGLQSEFQRA FRLMSENNAC ERLCKICEEY 370 380 390 400 410 420 QFLDITNEAN YGNTNTPFNT AYESFGCNHT VLPEAAAYPK PYYPPQITLS DGGNMNFLYY 430 440 450 460 470 IPDESNHQSY ENKANRDSDF QGQTSLTQGS APPWHYIPCQ SWLVWYPSED ASNPASGN

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329671 Genomic DNA. Translation: CAA20054.1.
PIR	T39522.
RefSeq	NP_595210.1. NM_001021117.2.
3D structure databases
ProteinModelPortal	O74326.
ModBase	Search...
Protein-protein interaction databases
STRING	4896.SPBC1685.06-1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPBC1685.06.1; SPBC1685.06.1:pep; SPBC1685.06.
GeneID	2539762.
KEGG	spo:SPBC1685.06.
Organism-specific databases
PomBase	SPBC1685.06.
Phylogenomic databases
eggNOG	COG5260.
OMA	ENNACER.
OrthoDB	EOG46QB1M.
Family and domain databases
InterPro	IPR002934. Nucleotidyltransferase. IPR002058. PAP_assoc. [Graphical view]
Pfam	PF01909. NTP_transf_2. 1 hit. PF03828. PAP_assoc. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20800912.

Entry information

Entry name

CID11_SCHPO

Accession

Primary (citable) accession number: O74326

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	November 1, 1998
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program