Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L5-B

Gene

rpl502

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.By similarity

Miscellaneous

There are two genes for L5 in S.pombe.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L5-B
Gene namesi
Name:rpl502
Synonyms:rpl5b
ORF Names:SPBC11C11.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC11C11.09c.
PomBaseiSPBC11C11.09c. rpl502.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001314531 – 29460S ribosomal protein L5-BAdd BLAST294

Proteomic databases

MaxQBiO74306.
PRIDEiO74306.

PTM databases

iPTMnetiO74306.

Interactioni

Subunit structurei

Component of the large ribosomal subunit (LSU).By similarity

Protein-protein interaction databases

BioGridi276235. 2 interactors.
MINTiMINT-4678105.
STRINGi4896.SPBC11C11.09c.1.

Structurei

3D structure databases

ProteinModelPortaliO74306.
SMRiO74306.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000105947.
InParanoidiO74306.
KOiK02932.
OMAiVAEYMES.
OrthoDBiEOG092C44EY.
PhylomeDBiO74306.

Family and domain databases

HAMAPiMF_01337_A. Ribosomal_L18_A. 1 hit.
InterProiView protein in InterPro
IPR005485. Rbsml_L5_euk/L18_arc.
IPR025607. Rbsml_L5e/L18P_C.
PANTHERiPTHR23410. PTHR23410. 1 hit.
PfamiView protein in Pfam
PF14204. Ribosomal_L18_c. 1 hit.
PF17144. Ribosomal_L5e. 1 hit.
PRINTSiPR00058. RIBOSOMALL5.

Sequencei

Sequence statusi: Complete.

O74306-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFIKAVKSS PYFSRYQTKY RRRREGKTDY YARKRLIAQA KNKYNAPKYR
60 70 80 90 100
LVVRFSNRFV TCQIVSSRVN GDYVLAHAHS SELPRYGIKW GLANWTAAYA
110 120 130 140 150
TGLLVARRAL AKVGLADKYE GVTEPEGEFE LTEAIEDGPR PFKVFLDVGL
160 170 180 190 200
KRTSTGSRVF GAMKGASDGG LFIPHSPNRF PGFDIETEEL DDETLRKYIY
210 220 230 240 250
GGHVAEYMEM LIDDDEERYQ KQFSGLIADG IESDQLEDIY AEAYAKIRED
260 270 280 290
PSFQKSGKDA AAFKAESLKY TQRKLTAEER KERFNAKVIE AGRA
Length:294
Mass (Da):33,486
Last modified:November 1, 1998 - v1
Checksum:iDA63FF578EB3E35F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA20691.1.
AB016045 mRNA. Translation: BAA31570.1.
PIRiT39325.
T43382.
RefSeqiNP_596399.1. NM_001022319.2.

Genome annotation databases

EnsemblFungiiSPBC11C11.09c.1; SPBC11C11.09c.1:pep; SPBC11C11.09c.
GeneIDi2539680.
KEGGispo:SPBC11C11.09c.

Similar proteinsi

Entry informationi

Entry nameiRL5B_SCHPO
AccessioniPrimary (citable) accession number: O74306
Secondary accession number(s): Q76N21
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: October 25, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families