O74242 (O74242_CRYNE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Plasma membrane H(+)-ATPase 1 EMBL AAC27788.1
EC=3.6.1.35 EMBL AAC27788.1

Gene names

Name:

pma1 EMBL AAC27788.1

Organism

Cryptococcus neoformans (Filobasidiella neoformans) EMBL AAC27788.1

Taxonomic identifier

5207 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Tremellaceae › Filobasidiella › Filobasidiella/Cryptococcus neoformans species complex

Protein attributes

Sequence length	997 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding RuleBase RU000653 SAAS SAAS004014 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS004014 RuleBase RU000653 EMBL AAC27788.1
PTM	Phosphoprotein SAAS SAAS004014 RuleBase RU000653
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro cation transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O74242 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: ECAEB09A66F7A744	FASTA	997	108,694
	10 20 30 40 50 60 MSDHEKVGHT EEIPTKESSL ENKVQGEEVP AAAAADEEPR KKREYKEMEH KTEGDLHAKV 70 80 90 100 110 120 DMNTIQFTAA DLYDKDKVDI EHVVMEEVYQ LLQCTDAGLT EAEATDRIGI FGPNKLEEKS 130 140 150 160 170 180 ENVLLQFLSF MWNPLSWVME GAALVAIALS NGGGTPPDWQ DFVGIILLLF VNSTIGFVEE 190 200 210 220 230 240 RNAGNAVKAL MDSLAPKARV KRDGQWKEIE SSELVPGDLI AFKHGDVCPS DCRLVEAIDV 250 260 270 280 290 300 SMDQAALTGE SLPVGKHEGD ECFSGSTCKQ GEAEGIVIAT GPNTFFGRAA TLVGQDNDQV 310 320 330 340 350 360 GHLQQVLARI GTFCLVSIGI FVLLEILILY ADFRYPYRRG LDNILVLLIG GIPIAMPTVL 370 380 390 400 410 420 SVTLAVGAQQ LAKHKAIVTR ITAIEELAGV TILCSDKTGT LTTNKLTIDK ENVKCYSKWD 430 440 450 460 470 480 VEGVCLLAAY ASRTENQDAI DGCVVGTLPD PQQARAGIKL LDFKPFNPVD KRTEITYRDE 490 500 510 520 530 540 MDGGKLKRAT KGMTGIIIEI CTRNKTNELE DQLEADVEEF ARRGLRALAV AFEDVAGDDP 550 560 570 580 590 600 SAEGNGFELV GLLSIFDPPR SDTKKTIDDA MALGVKVKMV TGDQLAIAKE TGRRLGLGDH 610 620 630 640 650 660 MYPAKVLKEG PEAGSKHANL DEMIMDADGF AGVFPEHKFE IVKRIQNLGH LCAMTGDGAN 670 680 690 700 710 720 DAPALSRANV GIAVEGATDA ARGAADIVLT EPGLSTIVHA IYGSRVIFQR MRNYAIYACA 730 740 750 760 770 780 VTIRIVLCFA IMAFAWRFDF PPFMVLIIAV LNDGTIMTLS LDRVLPSTTP DSWDLAEVFS 790 800 810 820 830 840 FGVAYGVYLS ASTIALYATM ENTTFFEDRF GVEPLKGNSY GGHMVIYLQV AIISQALIFV 850 860 870 880 890 900 TRSHGPSWTE RPSVALMLAF CLAQLVSSII AAYADWSFSQ VHSVSGGWIG IVWIWNIVWY 910 920 930 940 950 960 FPLDGIKFIM KKTVIAALQR RKARKAGPAV ADAALHRAPS RHESLYSNRT NFLTRAANRL 970 980 990 RGGAKISMSQ NELQRFSSIQ AQQSGAALTR AHSRPAA

References

[1]	"Sequencing and heterologous expression in Saccharomyces cerevisiae of a Cryptococcus neoformans cDNA encoding a plasma membrane H(+)-ATPase." Gorgojo B., Portillo F., Martinez-Suarez J.V. Biochim. Biophys. Acta 1509:103-110(2000) [PubMed: 11118522] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: B-3501 EMBL AAC27788.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF077766 mRNA. Translation: AAC27788.1.
3D structure databases
HSSP	HSSP built from PDB template 1MHS based on UniProtKB P07038.
ProteinModelPortal	O74242.
SMR	O74242. Positions 78-912.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus CNN01260 in contig AE017356_GR. Gene locus CNBN1250 in contig CM000053_GR.
Phylogenomic databases
eggNOG	fuNOG14103.
HOGENOM	HBG706356.
OMA	SHFQRAV.
OrthoDB	EOG47DDQ8.
PhylomeDB	O74242.
Family and domain databases
InterPro	IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR000695. ATPase_P-typ_H-transp. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR006534. ATPase_P-typ_PM_proton-efflux. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 2 hits. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 2 hits.
PANTHER	PTHR24093:SF61. PTHR24093:SF61. 1 hit.
Pfam	PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00120. HATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01647. ATPase-IIIA_H. 1 hit. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O74242_CRYNE

Accession

Primary (citable) accession number: O74242
Secondary accession number(s): Q55HJ5, Q5K735

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	December 14, 2011
This is version 94 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)