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Protein

Phosphoglycerate kinase

Gene

PGK

Organism
Funneliformis mosseae (Endomycorrhizal fungus) (Glomus mosseae)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (PGK)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei39SubstrateBy similarity1
Binding sitei122SubstrateBy similarity1
Binding sitei170SubstrateBy similarity1
Binding sitei219ATPBy similarity1
Binding sitei312ATP; via carbonyl oxygenBy similarity1
Binding sitei343ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi372 – 375ATPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:PGK
OrganismiFunneliformis mosseae (Endomycorrhizal fungus) (Glomus mosseae)
Taxonomic identifieri27381 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisMucoromycotaGlomeromycotinaGlomeromycetesGlomeralesGlomeraceaeFunneliformis

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001458811 – 416Phosphoglycerate kinaseAdd BLAST416

Proteomic databases

PRIDEiO74233

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO74233
SMRiO74233
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni24 – 26Substrate bindingBy similarity3
Regioni63 – 66Substrate bindingBy similarity4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 4 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

O74233-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSNKLSIR DLNVKDKRVL IRVDFNVPLD GTTITNNQRI VAALPTIKYA
60 70 80 90 100
LEQKAKTVVL MSHLGRPDGK KVDKYSLAPV AKEVERLLGK KVTFLEDCVG
110 120 130 140 150
EGVENYVKNA CDGEVILLEN LRFHAEEEGS SKGPDGKKVK ADLEKVKEFR
160 170 180 190 200
RSLTALGDVY INDAFGTAHR AHSSMVGVEL PQKAAGFLVK KELEYFAKAL
210 220 230 240 250
ESPERPFLAI LGGAKVSDKI QLIDNLIAKV DSLIICGGMA FTFKKTLENV
260 270 280 290 300
KIGNSLFDAD GAKTVGEVME KAKKHDVEVV LPVDYITADK FAKDAQVGYA
310 320 330 340 350
TDQEGIPDGW MGLDCGEKSV ELYKQTIAKA KTILWNGPAG VFEFDNFAKG
360 370 380 390 400
TKATLDCAVE AAQSGKIVII GGGDTATVAA KYGVEDKLSH VSTGGGASLE
410
LLEGKDLPGV SALSSK
Length:416
Mass (Da):44,765
Last modified:November 1, 1998 - v1
Checksum:i53179DF32EEFEC48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF072893 mRNA Translation: AAD09406.1
AF074394 mRNA Translation: AAC26131.1

Similar proteinsi

Entry informationi

Entry nameiPGK_FUNMO
AccessioniPrimary (citable) accession number: O74233
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

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