Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O74233 (PGK_FUNMO) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:PGK
OrganismFunneliformis mosseae (Endomycorrhizal fungus) (Glomus mosseae)
Taxonomic identifier27381 [NCBI]
Taxonomic lineageEukaryotaFungiGlomeromycotaGlomeromycetesGlomeralesGlomeraceaeFunneliformis

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145881

Regions

Nucleotide binding372 – 3754ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1221Substrate By similarity
Binding site1701Substrate By similarity
Binding site2191ATP By similarity
Binding site3121ATP; via carbonyl oxygen By similarity
Binding site3431ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
O74233 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 53179DF32EEFEC48

FASTA41644,765
        10         20         30         40         50         60 
MSLSNKLSIR DLNVKDKRVL IRVDFNVPLD GTTITNNQRI VAALPTIKYA LEQKAKTVVL 

        70         80         90        100        110        120 
MSHLGRPDGK KVDKYSLAPV AKEVERLLGK KVTFLEDCVG EGVENYVKNA CDGEVILLEN 

       130        140        150        160        170        180 
LRFHAEEEGS SKGPDGKKVK ADLEKVKEFR RSLTALGDVY INDAFGTAHR AHSSMVGVEL 

       190        200        210        220        230        240 
PQKAAGFLVK KELEYFAKAL ESPERPFLAI LGGAKVSDKI QLIDNLIAKV DSLIICGGMA 

       250        260        270        280        290        300 
FTFKKTLENV KIGNSLFDAD GAKTVGEVME KAKKHDVEVV LPVDYITADK FAKDAQVGYA 

       310        320        330        340        350        360 
TDQEGIPDGW MGLDCGEKSV ELYKQTIAKA KTILWNGPAG VFEFDNFAKG TKATLDCAVE 

       370        380        390        400        410 
AAQSGKIVII GGGDTATVAA KYGVEDKLSH VSTGGGASLE LLEGKDLPGV SALSSK 

« Hide

References

[1]"Isolation of the 3-phosphoglycerate kinase gene of the arbuscular mycorrhizal fungus Glomus mosseae (Nicol. & Gerd.) Gerdemann & Trappe."
Harrier L.A., Wright F., Hooker J.E.
Curr. Genet. 34:386-392(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: BEG 12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF072893 mRNA. Translation: AAD09406.1.
AF074394 mRNA. Translation: AAC26131.1.

3D structure databases

ProteinModelPortalO74233.
SMRO74233. Positions 2-416.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO74233.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_FUNMO
AccessionPrimary (citable) accession number: O74233
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: March 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways