Unreviewed, UniProtKB/TrEMBL O74229 (O74229_KLULA)

Names and origin

Protein names

Submitted name:
    KLLA0D01452p EMBL CAH00229.1
Submitted name:
    Cat8p EMBL AAC23607.1

Gene names

Name:	CAT8 EMBL AAC23607.1
Ordered Locus Names:	KLLA0D01452g

Organism

Kluyveromyces lactis (Yeast) (Candida sphaerica) [Complete proteome] EMBL AAC23607.1

Taxonomic identifier

28985 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces

Protein attributes

Sequence length	1445 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)

Sequence similarities

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation Spearmint SPM001138
Cellular component	Nucleus Spearmint SPM001138
Ligand	DNA-binding Spearmint SPM001138 Metal-binding Spearmint SPM001138 Zinc Spearmint SPM001138
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O74229-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 8FFE253861CACCA7	FASTA	1,445	159,281
	10 20 30 40 50 60 MVEKKDSAGR FNGQPSHGGP RFIRTLGSQS LSGLNPLSNA QQGVSQQQQH LSHHSHNVTD 70 80 90 100 110 120 SDSPSIQDSG IPITSALIKK ESPSHAVSGI PSNSNSINNN SKSNSNNNPS SVFSSRNNTS 130 140 150 160 170 180 IQQLQQGPSP TLSNSESPVN ASLLSSITTP LLHQTGSASH PPSNTGSSTN GTTTPSYRVA 190 200 210 220 230 240 QACDRCRAKK IRCDGKRPQC TQCAAVGFEC KISDKLSRRA FPRGYTETLE ERVRELEAEN 250 260 270 280 290 300 RRLVALCDLK EEQLHLVSKY SNSKDENGVE IPSTEEEQIL HELSKTNGGS LRVSSTNLYL 310 320 330 340 350 360 LNKKASPGDD SHIESSEPSI PVRKVAITAP SPRIMSPRNS VADSDPSQTN TGNNDHIHSN 370 380 390 400 410 420 NNNHNQNNST DPYGISFEQN EAPGLPALKA LSSLSKYKQG TQLATLVAVS VPRTTEEILF 430 440 450 460 470 480 VPQLLARIGQ IHGFTSKQCI YTASVLASLK ENNISSIPPE LEVLKNHNLW EIDDVLHFWK 490 500 510 520 530 540 NVFKLDFMTH TAVDHSSTHL NFAEVEELMQ LFFQDWYELI PLFDKNEFNS YYEKFKLNVT 550 560 570 580 590 600 DPNFFVRKDD TVFNNRTRSI SYKIFSCLLI IIVQMGMLSK IKRDKITSGK LSTLMKYYDK 610 620 630 640 650 660 LMTHIWINPY FNSRNTSIQV LQCLSMLLFY MLNVGDISSI YELRGKVVSM SQQLRLHRCP 670 680 690 700 710 720 SAVLGGDGST VSKVQQGERR ILFWSIYYLD VFSALQLGVP RLLKDFEIEC ALPVTSDDDR 730 740 750 760 770 780 QVNLAGQMIA LEGKVSQFSL SVIRFAKVMG NILDSTFKRG MTTSLTKQAA LVHENALDNW 790 800 810 820 830 840 RHGLQKDLFF QLDVNGTINM DEFNQQKQYS KSLSPRTAAF THNSLVLMTL YFMAKCMIHL 850 860 870 880 890 900 PVVATKPLVA EAIQTPTDNQ TENGSVDRSL SSYVLLQQAT NTLLNVLTAL NSIYLPLPIN 910 920 930 940 950 960 LARTKTRFGL FSARGSLEYT KGGALFQDNK ALLLDLVKEL ETDKKLELPG NTSWHSLKLF 970 980 990 1000 1010 1020 DLSINLILQP VNSNPEKTEK MIQKKINYYN KLMGQPTVAV KRKRDPKATE NTSKKVKVED 1030 1040 1050 1060 1070 1080 DHSQDNLHNI TTGETTDTVH SEELVKDVPK ELNVYPENYT TIEEAFQMDP VLNTNLFSNT 1090 1100 1110 1120 1130 1140 DLKTLFNSGI FENAGSIHNN INDNNNNNNN TNNTNNNNGS SRNIHNLGAG IEDIDHGMSL 1150 1160 1170 1180 1190 1200 RSNDASLLNL SNALGNHGNS AEGMKDGTSV SNLLNLSTSD SLFKVPSNGD FLKDYYINNM 1210 1220 1230 1240 1250 1260 SNTGLSNLHT SSVNKGPSLS QLGSLFMSSG SGTNLPYSNV RGESKHPSGV NLNKQRAQPA 1270 1280 1290 1300 1310 1320 MDGFSFAADA SLGLAPLLAW SPDAKPQLNS NNGNDGLNPA TGIVLESGDN DSTNASVVQL 1330 1340 1350 1360 1370 1380 QQHQQQTHHP PSHNSSSIPM GKQSSTSDRQ NSHHQDNVGS FHSMHSPTIP EQTSAQGLHQ 1390 1400 1410 1420 1430 1440 HQMLGMPNST LNSDTNTGGA NVTNSISSTN RRGPRRRWNN AASSSDPNSA GDSSVSDLLR WQNGN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Differences in regulation of yeast gluconeogenesis revealed by Cat8p-independent activation of PCK1 and FBP1 genes in Kluyveromyces lactis." Georis I., Krijger J.J., Breunig K.D., Vandenhaute J. Mol. Gen. Genet. 264:193-203(2000) [PubMed: 11016849] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CBS2359 EMBL AAC23607.1.
[2]	"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF070974 Genomic DNA. Translation: AAC23607.1. CR382124 Genomic DNA. Translation: CAH00229.1.
PIR	T14913.
RefSeq	XP_453133.1.
3D structure databases
HSSP	HSSP built from PDB template 1PYI based on UniProtKB P07272.
SMR	O74229. Positions 179-246.
ModBase	Search...
Protein-protein interaction databases
STRING	O74229.
Genome annotation databases
GeneID	2893022.
GenomeReviews	Gene locus KLLA0D01452g in contig CR382124_GR.
KEGG	kla:KLLA0D01452g.
Phylogenomic databases
eggNOG	fuNOG05586.
HOGENOM	HBG103921.
OrthoDB	EOG98963H.
PhylomeDB	O74229.
Family and domain databases
InterPro	IPR007219. Fungal_trans. IPR001138. Fungi_Trscrp_N. [Graphical view]
Pfam	PF04082. Fungal_trans. 1 hit. PF00172. Zn_clus. 1 hit. [Graphical view]
SMART	SM00066. GAL4. 1 hit. [Graphical view]
PROSITE	PS00463. ZN2_CY6_FUNGAL_1. 1 hit. PS50048. ZN2_CY6_FUNGAL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O74229_KLULA

Accession

Primary (citable) accession number: O74229
Secondary accession number(s): Q6CSF6

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	January 19, 2010
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)