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O74196 (UBC1_COLGL) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquitin-conjugating enzyme E2-16 kDa

EC=6.3.2.19
Alternative name(s):
Colletotrichum hard-surface-induced protein 1
Ubiquitin carrier protein
Ubiquitin-protein ligase
Gene names
Name:UBC1
Synonyms:CHIP1
OrganismColletotrichum gloeosporioides (Anthracnose fungus) (Glomerella cingulata)
Taxonomic identifier474922 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeGlomerellalesGlomerellaceaemitosporic GlomerellaceaeColletotrichum

Protein attributes

Sequence length147 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the covalent attachment of ubiquitin to other proteins. May also mediate selective proteolysis pathways.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Developmental stage

Expressed in the conidium during the process of appressorium formation.

Induction

By hard-surface contact. Ethylene and the host surface wax enhance this induction which is essential for appressorium formation.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
Gene Ontology (GO)
   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ubiquitin-protein transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 147147Ubiquitin-conjugating enzyme E2-16 kDa
PRO_0000082542

Sites

Active site1071Glycyl thioester intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
O74196 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 6B65B0BE2F37D528

FASTA14716,528
        10         20         30         40         50         60 
MAFKRINKEL TDLGRDPPSS CSAGPVGEDL FHWQATIMGP GDSPYSGGVF FLAIHFPTDY 

        70         80         90        100        110        120 
PFKPPKVNFT TRIYHPNINS NGSICLDILR DQWSPALTIS KVLLSICSML TDPNPDEPLV 

       130        140 
PEIAHVYKTD RARYEATARE WTRKYAI 

« Hide

References

[1]"Identification of a gene product induced by hard-surface contact of Colletotrichum gloeosporioides conidia as a ubiquitin-conjugating enzyme by yeast complementation."
Liu Z.-M., Kolattukudy P.E.
J. Bacteriol. 180:3592-3597(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Conidium.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF030296 mRNA. Translation: AAC39499.1.

3D structure databases

ProteinModelPortalO74196.
SMRO74196. Positions 1-147.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D3.10.110.10. 1 hit.
InterProIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMSSF54495. SSF54495. 1 hit.
PROSITEPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBC1_COLGL
AccessionPrimary (citable) accession number: O74196
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: November 1, 1998
Last modified: October 16, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways