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Protein
Submitted name:

ALK5

Gene

ALK5

Organism
Yarrowia lipolytica (Candida lipolytica)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ALK5Imported
Gene namesi
Name:ALK5Imported
OrganismiYarrowia lipolytica (Candida lipolytica)Imported
Taxonomic identifieri4952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500416054719 – 531Sequence analysisAdd BLAST513

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_500856.1.

Structurei

3D structure databases

ProteinModelPortaliO74131.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000170996.
PhylomeDBiO74131.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002974. Cyt_P450_E_CYP52.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00464. EP450II.
PR01239. EP450IICYP52.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74131-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQLFGVLVL ALTTALLAQL AYNKYEYNRK VKQFGCGELT VAKNGFLGWK
60 70 80 90 100
GIRAVLHVLK TKKGPAALKE RIDAYGRTYV FHIGPAPVIS TMEPENIKAM
110 120 130 140 150
LATQFKDFSL GTRYRSLAPT LGDGIFTLDG HGWTHSRALL RPQFAREQVS
160 170 180 190 200
RLDSLEAHFQ ILKMCVDKEM REKGNDPRGF DIQNLFFLFT LDSATEFLFG
210 220 230 240 250
SSVDSLVDFL DDPSVRTGDH GGVDEAARKG FNNSFNHAQE LCALRSRLHT
260 270 280 290 300
LYWIVGSVVK KEPFERYNKE IKTFVDFFAA KALKARKEKD MSLMDNDQYI
310 320 330 340 350
FMYELVKETT NPVTLRDQML NILLAGRDTT ASMLSWIYFR LARDPKLYAK
360 370 380 390 400
LRSAILEDFG TTPEAITFES LKQCDYLRYV LNEALRLYPV VPINGRTATR
410 420 430 440 450
DTTLPRGGGP DQSQPIFIPK GQTVSYSVYW THRDPRFWGE DAEEFIPERW
460 470 480 490 500
DPRNGNIGRG WEYLPFNGGP RICLGQQFAL TEVGYVLSRL VQTYETLETC
510 520 530
DHKPLPPLYN HALTMCHEEG VWVKMYKGEK A
Length:531
Mass (Da):60,606
Last modified:November 1, 1998 - v1
Checksum:i8B3C8906D78AFA1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010392 Genomic DNA. Translation: BAA31437.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010392 Genomic DNA. Translation: BAA31437.1.

3D structure databases

ProteinModelPortaliO74131.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4952.XP_500856.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000170996.
PhylomeDBiO74131.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002974. Cyt_P450_E_CYP52.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00464. EP450II.
PR01239. EP450IICYP52.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO74131_YARLL
AccessioniPrimary (citable) accession number: O74131
Secondary accession number(s): Q6CEQ6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 16, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.