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O74088

- O74088_PYRHO

UniProt

O74088 - O74088_PYRHO

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Protein
Submitted name:

Putative uncharacterized protein PH0242

Gene

PH0242

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi556 – 5561CalciumImported
Metal bindingi765 – 7651Calcium; via carbonyl oxygenImported
Metal bindingi799 – 7991Calcium; via carbonyl oxygenImported
Metal bindingi802 – 8021CalciumImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. oligosaccharyl transferase activity Source: InterPro

GO - Biological processi

  1. protein glycosylation Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumImported, Metal-bindingImported

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-233-MONOMER.

Protein family/group databases

CAZyiGT66. Glycosyltransferase Family 66.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein PH0242Imported
Gene namesi
Ordered Locus Names:PH0242Imported
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)Imported
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000752: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi70601.PH0242.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VU1X-ray2.70A/B482-976[»]
ProteinModelPortaliO74088.
SMRiO74088. Positions 489-972.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1287.
HOGENOMiHOG000073801.
KOiK07151.
OMAiGYWIESS.

Family and domain databases

InterProiIPR003674. Oligo_trans_STT3.
[Graphical view]
PfamiPF02516. STT3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74088-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKSKVKKVE KGKEGEEKRS TYVLLKKVLI PILVFGFAIY AFYLRHLTAG
60 70 80 90 100
KYFPDPDTFY HFEIYKLVLK EGLPRYYPMS DAPFGSLIGE PLGLYLLPAA
110 120 130 140 150
FYKVVSLFGY NELQAFLLWP PFVGFLGVIA VYLLGRKVLN EWTGLWGAVV
160 170 180 190 200
LTVSTANFSR TFSGNARGDG PFMALFIFAS VAMLYYLKES NKTRKIIYGT
210 220 230 240 250
LFVLLTVISL GAWNGSPFGL MVLLGFASLQ TIILFIFGKL EELKKFVKEF
260 270 280 290 300
YPAYLAILAF GYALTFPGIV KIGGFIRFAF EVFLGLIFLL VIMLYGGRYL
310 320 330 340 350
NYSDKKHRFL VVTIIVLLGF GGAYAYVGPK LFRLMGGAYQ STQVYETVQE
360 370 380 390 400
LAKTTIGDVK AYYGVESGNG LIFFLSIPGL LILLTKYLYD LFKKAKSDNE
410 420 430 440 450
TLFALVFYTM SLYLLYLAVR FLFLASYAVA LFFGIFIGFS MDVIEKMKEN
460 470 480 490 500
IGIKAALGIV LSLMILVIPF VHAPVLARSA RALKNTEIEV TGWEQALKWL
510 520 530 540 550
RSNTSKYATA TSWWDYGYWI ESSLLGNRRA SADGGHARDR DHILALFLAR
560 570 580 590 600
DGNISEVDFE SWELNYFIIY LNDWAKFNAI SYLGGAITRK EYNGDENGRG
610 620 630 640 650
RVTTILLTQA AGNVYVNPYA RIVIKVIQQN KTRRIAVNIG QLECSPILSV
660 670 680 690 700
AFPGNIKIKG SGRCSDGSPF PYVVYLTPSL GVLAYYKVAT SNFVKLAFGI
710 720 730 740 750
PTSSYSEFAE KLFSNFIPVY QYGSVIVYEF RPFAIYKIED FINGTWREVG
760 770 780 790 800
KLSPGKHTLR LYISAFGRDI KNATLYVYAL NGTKIIKRIK VGEIKYMNHL
810 820 830 840 850
EEYPIIVNVT LPTAQKYRFI LAQKGPVGVL TGPVRVNGKI TNPAYIMREG
860 870 880 890 900
ESGRLELKVG VDKEYTADLY LRATFIYLVR KGGKSNEDYD ASFEPHMDTF
910 920 930 940 950
FITKLKEGIK LRPGENEIVV NAEMPKNAIS SYKEKLEKEH GDKLIIRGIR
960 970
VEPVFIVEKE YTMIEVSASA PHHSSE
Length:976
Mass (Da):109,970
Last modified:November 1, 1998 - v1
Checksum:iBF5FB82FBADC60A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000001 Genomic DNA. Translation: BAA29314.1.
PIRiC71248.
RefSeqiNP_142238.1. NC_000961.1.
WP_010884345.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA29314; BAA29314; BAA29314.
GeneIDi1444132.
KEGGipho:PH0242.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000001 Genomic DNA. Translation: BAA29314.1 .
PIRi C71248.
RefSeqi NP_142238.1. NC_000961.1.
WP_010884345.1. NC_000961.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3VU1 X-ray 2.70 A/B 482-976 [» ]
ProteinModelPortali O74088.
SMRi O74088. Positions 489-972.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 70601.PH0242.

Protein family/group databases

CAZyi GT66. Glycosyltransferase Family 66.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA29314 ; BAA29314 ; BAA29314 .
GeneIDi 1444132.
KEGGi pho:PH0242.

Phylogenomic databases

eggNOGi COG1287.
HOGENOMi HOG000073801.
KOi K07151.
OMAi GYWIESS.

Enzyme and pathway databases

BioCyci PHOR70601:GJWR-233-MONOMER.

Family and domain databases

InterProi IPR003674. Oligo_trans_STT3.
[Graphical view ]
Pfami PF02516. STT3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3Imported.
  2. "Crystallographic and NMR evidence for flexibility in oligosaccharyltransferases and its catalytic significance."
    Nyirenda J., Matsumoto S., Saitoh T., Maita N., Noda N.N., Inagaki F., Kohda D.
    Structure 21:32-41(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 482-976 IN COMPLEX WITH CALCIUM.

Entry informationi

Entry nameiO74088_PYRHO
AccessioniPrimary (citable) accession number: O74088
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3