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Protein

DNA polymerase

Gene

pol1

Organism
Cenarchaeum symbiosum (strain A)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA replicationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
Name:pol1Imported
OrganismiCenarchaeum symbiosum (strain A)Imported
Taxonomic identifieri414004 [NCBI]
Taxonomic lineageiArchaeaThaumarchaeotaCenarchaealesCenarchaeaceaeCenarchaeum
Proteomesi
  • UP000000758 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliO74046.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 352DNA_pol_B_exo1InterPro annotationAdd BLAST319
Domaini407 – 800DNA_pol_BInterPro annotationAdd BLAST394

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00136. DNA_pol_B. 1 hit.
PF03104. DNA_pol_B_exo1. 1 hit.
[Graphical view]
PRINTSiPR00106. DNAPOLB.
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiPS00116. DNA_POLYMERASE_B. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74046-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAQDEEIPP SLLVSATYDG QARAVVLKFY ESESQKIIHW TDNTGHKPYC
60 70 80 90 100
YTRLPPSELG FLGGREDVLG IEQVMRHDLI ADKEVPVSKI TVSDPLAIGG
110 120 130 140 150
THSEKSIRNV IDTWESDIKY YENYLYDAGL VVGRYYSVSG GEVIPHDMPI
160 170 180 190 200
SDEVKLALKS LLWDKLIDEG MADRKEFREF IAGWADLLNQ PIPRIRRLSF
210 220 230 240 250
DIEVDSEEGR IPDAKISDRR VTAVGFAATD GLRKVLVLKS GADEGANDVT
260 270 280 290 300
PGVEVVFYDE DKEADMIRDA LAIIGSYPFV LTYNGDDFDM PYMYNRARRL
310 320 330 340 350
GVADSDIPLY MMRDSATLRH GVHLDLYRTF SNRSFQLYAF AAKYTDYSLN
360 370 380 390 400
SVSKAMLGEG KVDYGVSLGD LTLYQTANYC YHDARLTLEL STFGNEILMD
410 420 430 440 450
LLVVTSRIAR MPIDDMSRMG VSQWIRSLLY YEHRQRNALI PRRDELEKRS
460 470 480 490 500
QQVSNDAVIK DKKFRGGLVV EPEEGIHFDV TVMDFASLYP SIIKVRNLSY
510 520 530 540 550
ETVRCVHPEC RKNTIPDTNH WVCTKNNGLT SMIIGSLRDL RVNYYKSLSK
560 570 580 590 600
SQSITEEQRQ QYTVISQALK VVLNASYGVM GAEIFPLYFL PAAEATTAVG
610 620 630 640 650
RYIIMQTISH CEQMGVKVLY GDTDSLFIKN PEERQIHDIV EHAKKEHGVE
660 670 680 690 700
LEVDKEYRYV VLSNRKKNYF GVTKSGKVDV KGLTGKKSHT PPFIKELFYS
710 720 730 740 750
LLDILSAVQT EDEFESAKLK ISKAIAASGK RLEERGVPLA DLAFNVMISK
760 770 780 790 800
APSEYVKTVP QHIRAARLLE NAREVKKGDI ISYVKVMNKT GVKPVEMAQA
810 820 830 840
GEVDTSKYLE FMESTLDQLT SSMGLDFDEM LGKPKQTGME QFFFK
Length:845
Mass (Da):95,592
Last modified:November 1, 1998 - v1
Checksum:iDB294533773E2BAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF083071 Genomic DNA. Translation: AAC62689.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF083071 Genomic DNA. Translation: AAC62689.1.

3D structure databases

ProteinModelPortaliO74046.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00136. DNA_pol_B. 1 hit.
PF03104. DNA_pol_B_exo1. 1 hit.
[Graphical view]
PRINTSiPR00106. DNAPOLB.
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiPS00116. DNA_POLYMERASE_B. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO74046_CENSY
AccessioniPrimary (citable) accession number: O74046
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.