O74019 (RPOH_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit H
EC=2.7.7.6

Gene names

Name:	rpoH
Ordered Locus Names:	PH1546.1
ORF Names:	PHS044

Organism

Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]

Taxonomic identifier

70601 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	82 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00025
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00025
Sequence similarities	Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 82	82	DNA-directed RNA polymerase subunit H HAMAP MF_00025		PRO_0000146101

Sequences

	Sequence		Length	Mass (Da)
	O74019 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 8D8A7C5C901DFC69	FASTA	82	9,355
	10 20 30 40 50 60 MSGKNEFNIF KHVLVPEHRI LSEEEKKALL EKYKITPAQL PQIRASDPAV KALGAKPGDI 70 80 IEIKRRSPTA GVYYYYRVVV ED

References

[1]

"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3." Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H. DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000001 Genomic DNA. Translation: BAA30658.1.
PIR	B71032.
RefSeq	NP_143408.1. NC_000961.1.
3D structure databases
ProteinModelPortal	O74019.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000001353; EBPYRP00000001353; EBPYRG00000001353.
GeneID	1443866.
GenomeReviews	Gene locus PH1546.1 in contig BA000001_GR.
KEGG	pho:PHS044.
NMPDR	fig|70601.1.peg.1519.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000023233.
HOGENOM	HBG496846.
OMA	EHELVPK.
ProtClustDB	PRK09570.
Enzyme and pathway databases
BioCyc	PHOR70601:PHS044-MONOMER.
Family and domain databases
HAMAP	MF_00025. RNApol_arch_H. [Tree]
InterPro	IPR020609. DNA-dir_RNA_pol_subH/Rpb5_arc. IPR000783. RNA_pol_subH/Rpb5_C. IPR020608. RNA_pol_subH/Rpb5_CS. [Graphical view]
Gene3D	G3DSA:3.90.940.20. RNApol_RPB5. 1 hit.
KO	K03053.
Pfam	PF01191. RNA_pol_Rpb5_C. 1 hit. [Graphical view]
ProDom	PD005155. RNA_pol_subH/Rpb5_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF55287. RNApol_RPB5_like. 1 hit.
PROSITE	PS01110. RNA_POL_H_23KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOH_PYRHO

Accession

Primary (citable) accession number: O74019

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	November 16, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program