ID   PORA_PYRHO              Reviewed;         395 AA.
AC   O73986; O58416;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   05-MAY-2009, entry version 44.
DE   RecName: Full=Pyruvate synthase subunit porA;
DE            EC=1.2.7.1;
DE   AltName: Full=Pyruvate oxidoreductase alpha chain;
DE            Short=POR;
DE   AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit alpha;
GN   Name=porA; OrderedLocusNames=PH0684;
OS   Pyrococcus horikoshii.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=53953;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OT3;
RX   MEDLINE=98344137; PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y.,
RA   Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y.,
RA   Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K.,
RA   Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin =
CC       acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+).
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one
CC       gamma chain (By similarity).
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DR   EMBL; BA000001; BAA29775.1; ALT_INIT; Genomic_DNA.
DR   PIR; E71114; E71114.
DR   RefSeq; NP_142633.1; -.
DR   GeneID; 1443011; -.
DR   GenomeReviews; BA000001_GR; PH0684.
DR   KEGG; pho:PH0684; -.
DR   NMPDR; fig|70601.1.peg.664; -.
DR   HOGENOM; O73986; -.
DR   OMA; O73986; LYQASGM.
DR   BRENDA; 1.2.7.1; 74679.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR015941; Transketolase_C-like.
DR   Gene3D; G3DSA:3.40.50.920; Transketo_C_like; 1.
DR   Pfam; PF01855; POR_N; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    395       Pyruvate synthase subunit porA.
FT                                /FTId=PRO_0000099901.
SQ   SEQUENCE   395 AA;  43911 MW;  A49B2DADA3B9AC00 CRC64;
     MPIRTVMKAN EAAAWAAKLA KPKVIAAFPI TPSTLVPEKI SEFVANGELD AEFIKVESEH
     SAISAVVGAS AAGVRTFTAT ASQGLALMHE VLFIAAGMRL PIVMAIGNRS LSAPINIWND
     WQDSISQRDT GWIQFYAENN QEALDLILLA YKVAEDERVL LPAMVGFDAF ILTHTVEPVE
     IPDQEVVDEF LGEYEPKHAY LDPKRPITQG TLAFPAHYME AKYLVWDAME KARKVIDEAF
     AEFEKRFGRK YQKIEEYKTD DAEIIFVTMG SLAGTLKDWV DKKREEGYKV GAAKMTVYRP
     FPVEEIRALA KKAKVLGFIE KDISIGLYGA VFIDASAALV NESERPLMLD FIAGLGGRDV
     TFGQLDDALR IAEEALEKGE VEKPIHWIGL RKELL
//