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Protein
Submitted name:

Fork head domain protein FKD6

Gene

foxd3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi96 – 190Fork-headPROSITE-ProRule annotationAdd BLAST95

GO - Molecular functioni

  • DNA binding transcription factor activity Source: ZFIN
  • sequence-specific DNA binding Source: ZFIN

GO - Biological processi

  • cartilage development Source: ZFIN
  • cartilage development involved in endochondral bone morphogenesis Source: ZFIN
  • enteric nervous system development Source: ZFIN
  • iridophore differentiation Source: ZFIN
  • lateral line nerve glial cell development Source: ZFIN
  • melanocyte differentiation Source: ZFIN
  • negative regulation of gene expression Source: ZFIN
  • negative regulation of transcription, DNA-templated Source: ZFIN
  • neural crest cell development Source: ZFIN
  • neural crest cell migration Source: ZFIN
  • peripheral nervous system development Source: ZFIN
  • pigment cell differentiation Source: ZFIN
  • response to thyroid hormone Source: ZFIN
  • sympathetic nervous system development Source: ZFIN
  • transcription by RNA polymerase II Source: ZFIN

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Fork head domain protein FKD6Imported
Gene namesi
Name:foxd3Imported
Synonyms:fkd6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-143 foxd3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Structurei

3D structure databases

ProteinModelPortaliO73782
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 190Fork-headInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
HOGENOMiHOG000231285
HOVERGENiHBG051641

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00657 FORK_HEAD_1, 1 hit
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequencei

Sequence statusi: Complete.

O73782-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSGGTSAS NMSGQTVLTA DDVDIDVVGE GDEGMEQDSD CESQCMQDRG
60 70 80 90 100
DEVEEIEVKE RSTSPCESNA DGETKGDAQE SSTGPMQNKP KSSLVKPPYS
110 120 130 140 150
YIALITMAIL QSPQKKLTLS GICEFISNRF PYYREKFPAW QNSIRHNLSL
160 170 180 190 200
NDCFVKIPRE PGNPGKGNYW TLDPQSEDMF DNGSFLRRRK RFKRHQPDIL
210 220 230 240 250
RDQTALMMQS FGAYGIGNPY GRHYGIHPAA YTHPAALQYP YIPPVGPMLP
260 270 280 290 300
PAVPLLPSAE LNRKAFSSQL SPSLQLQLNS LSTASIIKSE PSSRPSFSIE
310 320 330 340 350
NIIGVSSSLR AIQTFLRPPV TVQSALLSAQ SLSLTRTSAA IAPILSVPSN
360 370
IISGQFLPTA STAAVSKWPS Q
Length:371
Mass (Da):40,476
Last modified:August 1, 1998 - v1
Checksum:i5DDD1011466BCB74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052249 mRNA Translation: AAC06366.1
UniGeneiDr.75816

Similar proteinsi

Entry informationi

Entry nameiO73782_DANRE
AccessioniPrimary (citable) accession number: O73782
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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