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Protein
Submitted name:

Fork head domain protein FKD6

Gene

foxd3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • sequence-specific DNA binding Source: ZFIN
  • transcription factor activity, sequence-specific DNA binding Source: ZFIN

GO - Biological processi

  • cartilage development Source: ZFIN
  • cartilage development involved in endochondral bone morphogenesis Source: ZFIN
  • enteric nervous system development Source: ZFIN
  • iridophore differentiation Source: ZFIN
  • lateral line nerve glial cell development Source: ZFIN
  • melanocyte differentiation Source: ZFIN
  • negative regulation of gene expression Source: ZFIN
  • negative regulation of transcription, DNA-templated Source: ZFIN
  • neural crest cell development Source: ZFIN
  • neural crest cell migration Source: ZFIN
  • peripheral nervous system development Source: ZFIN
  • pigment cell differentiation Source: ZFIN
  • sympathetic nervous system development Source: ZFIN
  • transcription from RNA polymerase II promoter Source: ZFIN
Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Fork head domain protein FKD6Imported
Gene namesi
Name:foxd3Imported
Synonyms:fkd6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-143. foxd3.

PTM / Processingi

Proteomic databases

PaxDbiO73782.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000107660.

Structurei

3D structure databases

ProteinModelPortaliO73782.
SMRiO73782. Positions 95-191.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini96 – 19095Fork-head DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
HOGENOMiHOG000231285.
HOVERGENiHBG051641.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. Fork_head_dom.
IPR018122. TF_fork_head_CS_1.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Forkhead. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O73782-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSGGTSAS NMSGQTVLTA DDVDIDVVGE GDEGMEQDSD CESQCMQDRG
60 70 80 90 100
DEVEEIEVKE RSTSPCESNA DGETKGDAQE SSTGPMQNKP KSSLVKPPYS
110 120 130 140 150
YIALITMAIL QSPQKKLTLS GICEFISNRF PYYREKFPAW QNSIRHNLSL
160 170 180 190 200
NDCFVKIPRE PGNPGKGNYW TLDPQSEDMF DNGSFLRRRK RFKRHQPDIL
210 220 230 240 250
RDQTALMMQS FGAYGIGNPY GRHYGIHPAA YTHPAALQYP YIPPVGPMLP
260 270 280 290 300
PAVPLLPSAE LNRKAFSSQL SPSLQLQLNS LSTASIIKSE PSSRPSFSIE
310 320 330 340 350
NIIGVSSSLR AIQTFLRPPV TVQSALLSAQ SLSLTRTSAA IAPILSVPSN
360 370
IISGQFLPTA STAAVSKWPS Q
Length:371
Mass (Da):40,476
Last modified:August 1, 1998 - v1
Checksum:i5DDD1011466BCB74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052249 mRNA. Translation: AAC06366.1.
UniGeneiDr.75816.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052249 mRNA. Translation: AAC06366.1.
UniGeneiDr.75816.

3D structure databases

ProteinModelPortaliO73782.
SMRiO73782. Positions 95-191.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000107660.

Proteomic databases

PaxDbiO73782.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-980526-143. foxd3.

Phylogenomic databases

eggNOGiKOG2294. Eukaryota.
COG5025. LUCA.
HOGENOMiHOG000231285.
HOVERGENiHBG051641.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. Fork_head_dom.
IPR018122. TF_fork_head_CS_1.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Forkhead. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO73782_DANRE
AccessioniPrimary (citable) accession number: O73782
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.