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Protein
Submitted name:

Neuropeptide Y/peptide YY receptor Ya

Gene

npy4r

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • neuropeptide binding Source: ZFIN
  • neuropeptide Y receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, NeuropeptideImported, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Neuropeptide Y/peptide YY receptor YaImported
Gene namesi
Name:npy4rImported
Synonyms:NPYRYAImported, npyryaImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-393. npy4r.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei43 – 6826HelicalSequence analysisAdd
BLAST
Transmembranei80 – 10526HelicalSequence analysisAdd
BLAST
Transmembranei117 – 13822HelicalSequence analysisAdd
BLAST
Transmembranei158 – 18124HelicalSequence analysisAdd
BLAST
Transmembranei218 – 23720HelicalSequence analysisAdd
BLAST
Transmembranei267 – 28519HelicalSequence analysisAdd
BLAST
Transmembranei305 – 32925HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO73733.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000063623.

Structurei

3D structure databases

ProteinModelPortaliO73733.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini59 – 326268G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG105676.
KOiK04206.
PhylomeDBiO73733.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000351. NPY1_rcpt.
IPR000611. NPY_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01013. NRPEPTIDEY1R.
PR01012. NRPEPTIDEYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O73733-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSALFDMPL WQALLNSTLT HNQSNSSLFL LDVPCWQSST MTLTLVLCYC
60 70 80 90 100
LVLILGLLGN ILLICIIMHQ RDPPNVTSIL IANLSVSDIL VSVFCLPFTV
110 120 130 140 150
VYTLMDHWIF GALLCRLMPF VQCVSVTVSV LSLVLIALER HQLILHPSGW
160 170 180 190 200
KPSVPQAYIA VLTVWLLACV TSLPFLAFHL LTSEPYSLFP APLSQLQVCL
210 220 230 240 250
EVWPSQDHKL AYTTSLLLFQ YCCPLLLMLL CYLRIFLRLQ RRERMLERQC
260 270 280 290 300
SRNREDEHRR VMHSKRINVM LATLVAAFAV CWLPLNAFNV VADCDQEVLP
310 320 330 340 350
VCNHNLLFSL CHLLAMSSTC VNPIIYGFLN SNFRKDVASV VLHCHFQPLE
360 370
DSYEHFPMST MNTDVSRTSF RLRNNSV
Length:377
Mass (Da):42,902
Last modified:August 1, 1998 - v1
Checksum:i60E62AD9C7BFE5D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037400 Genomic DNA. Translation: AAC41276.1.
RefSeqiNP_571515.1. NM_131440.1.
UniGeneiDr.45879.

Genome annotation databases

GeneIDi30717.
KEGGidre:30717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037400 Genomic DNA. Translation: AAC41276.1.
RefSeqiNP_571515.1. NM_131440.1.
UniGeneiDr.45879.

3D structure databases

ProteinModelPortaliO73733.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000063623.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiO73733.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30717.
KEGGidre:30717.

Organism-specific databases

CTDi5540.
ZFINiZDB-GENE-980526-393. npy4r.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG105676.
KOiK04206.
PhylomeDBiO73733.

Miscellaneous databases

NextBioi20807066.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000351. NPY1_rcpt.
IPR000611. NPY_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01013. NRPEPTIDEY1R.
PR01012. NRPEPTIDEYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Multiplicity of neuropeptide Y receptors: cloning of a third distinct subtype in the zebrafish."
    Ringvall M., Berglund M.M., Larhammar D.
    Biochem. Biophys. Res. Commun. 241:749-755(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Cloning and characterization of a novel neuropeptide Y receptor subtype in the zebrafish."
    Lundell I., Berglund M.M., Starback P., Salaneck S., Gehlert D.R., Larhammar D.
    DNA Cell Biol. 16:1357-1363(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Neuropeptide Y receptor subtype with unique properties cloned in the zebrafish: the zYa receptor."
    Starback P., Lundell I., Fredriksson R., Berglund M.M., Yan Y.L., Wraith A., Soderberg C., Postlethwait J.H., Larhammar D.
    Brain Res. Mol. Brain Res. 70:242-252(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO73733_DANRE
AccessioniPrimary (citable) accession number: O73733
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.