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Protein
Submitted name:

Homeobox protein PDX-1

Gene

pdx1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi137 – 196HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

  • determination of digestive tract left/right asymmetry Source: ZFIN
  • determination of liver left/right asymmetry Source: ZFIN
  • determination of pancreatic left/right asymmetry Source: ZFIN
  • endocrine pancreas development Source: ZFIN
  • glucose homeostasis Source: ZFIN
  • pancreas development Source: ZFIN

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox protein PDX-1Imported
Gene namesi
Name:pdx1Imported
Synonyms:ipf1Imported, pdx-1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-122 pdx1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO73726
SMRiO73726
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 195HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the Antp homeobox family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0489 Eukaryota
ENOG410ZTBY LUCA
HOGENOMiHOG000115484
HOVERGENiHBG004525

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00025 ANTENNAPEDIA
PR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

O73726-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNREEHYYPP NHLYKDSCAF QRHPNEDYSQ NPPPCLYMRQ AHSVYASPLG
60 70 80 90 100
AQDQPNLTDI TSYNMSSRDD PAGPHLHLPQ TSQTSLQSLG GYGDSLDLCG
110 120 130 140 150
DRNRYHLPFP WMKSTKSHTH AWKGQWTGPY MVEAEENKRT RTAYTRAQLL
160 170 180 190 200
ELEKEFLFNK YISRPRRVEL ALTLSLTERH IKIWFQNRRM KWKKEEDKRR
210 220 230 240
ARGVDPEQDS SITSGDLKDE SCVGTATLAG PPSPLHPHAP SVQQDS
Length:246
Mass (Da):28,366
Last modified:August 1, 1998 - v1
Checksum:iA15DDB2F8C3882C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF036325 mRNA Translation: AAC41260.1
UniGeneiDr.75810

Similar proteinsi

Entry informationi

Entry nameiO73726_DANRE
AccessioniPrimary (citable) accession number: O73726
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)