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Protein
Submitted name:

25-hydroxyvitamin D3 24-hydroxylase

Gene

cP450cc24

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • bone regeneration Source: AgBase
  • vitamin D3 catabolic process Source: AgBase

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

SABIO-RKiO73684.

Names & Taxonomyi

Protein namesi
Submitted name:
25-hydroxyvitamin D3 24-hydroxylaseImported
Gene namesi
Name:cP450cc24Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

PTM / Processingi

Proteomic databases

PaxDbiO73684.

Structurei

3D structure databases

ProteinModelPortaliO73684.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0159. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000276540.
HOVERGENiHBG099053.
PhylomeDBiO73684.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

O73684-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGCSILLRS SALTCGRPRS SPPGAEVRCR GRRPLCALRG RGHPLAALPG
60 70 80 90 100
PPSWPLMGSL PDVLWKGGLK RQHETLAEYH RRFGKIFRMK LGAFDSVHIG
110 120 130 140 150
APCLLESLYR RESSCPQRLE IKPWKAYRDY RDEGYGLLIL EGKDWQRVRS
160 170 180 190 200
AFQKKLMKPK EVVKLDNTIN EVLEDFMHRI DEICNHNGQM EDVYSEFNKW
210 220 230 240 250
SFESICLVLY GKRFGLLQQD VEEESLNFIK AVKTMMATFG MMMVTPVELH
260 270 280 290 300
KGLNTKVWQA HTKAWDDIFK TAKHSIDSRL QRHSANPQED FLCDIYSGGQ
310 320 330 340 350
LSKKELYATI AELQIAGVET TANSLLWALY NISRNPHVQQ KLLQEIQSVL
360 370 380 390 400
AANESPTAES IKNMPYLKAC LKESMRLTPS VPFTTRTIDT EMVLGDYVLP
410 420 430 440 450
EGTVLMINSY ALGCNEEYFN GWTQFKPERR WLQKHSINPF SHVPFGIGKR
460 470 480 490 500
MCIGRRLAEL QLHLALCWII RKYQLVATDD NPVETLHSGI LIPSRELPIA

FHRRLQLD
Length:508
Mass (Da):58,128
Last modified:August 1, 1998 - v1
Checksum:i8C0DB4EBBE2CBAD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF019142 mRNA. Translation: AAC41266.1.
RefSeqiNP_990310.1. NM_204979.1.
UniGeneiGga.893.

Genome annotation databases

GeneIDi395827.

Similar proteinsi

Entry informationi

Entry nameiO73684_CHICK
AccessioniPrimary (citable) accession number: O73684
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 27, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)