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Protein
Submitted name:

Neuronal leucine-rich repeat protein

Gene

XNLRR-1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal leucine-rich repeat proteinImported
Gene namesi
Name:XNLRR-1Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei632 – 65524HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 718694Sequence analysisPRO_5004160532Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO73675.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini426 – 51792Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini525 – 61995Fibronectin type-IIIInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains LRRCT domain.SAAS annotation
Contains LRRNT domain.SAAS annotation

Keywords - Domaini

Immunoglobulin domainSAAS annotation, Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG052361.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
3.80.10.10. 3 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF07679. I-set. 1 hit.
PF13855. LRR_8. 4 hits.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00408. IGc2. 1 hit.
SM00369. LRR_TYP. 9 hits.
SM00082. LRRCT. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF49265. SSF49265. 1 hit.
SSF52058. SSF52058. 1 hit.
PROSITEiPS50853. FN3. 1 hit.
PS50835. IG_LIKE. 1 hit.
PS51450. LRR. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O73675-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARISVLVLT ACQLLLGLLT SSLTDSSAPA NECPQLCVCE IRPWFTPQST
60 70 80 90 100
YREATTVDCN DLRLTKIPAN LSLDTQVLLL QSNNIGKTNG ELQRLVNLTE
110 120 130 140 150
LDLSQNNFTS IHDVGLSNLS QLTTLHLEEN QIFEMTDYCL QDLTNLQELY
160 170 180 190 200
INHNQLNSIS PSAFSGLRNL LRLHLNSNKL RIIDSRWFES TPNLEILMIG
210 220 230 240 250
ENPVIGILDL NFQPLVNLRS LVLAGMYLSD IPGNALLGLD NLESLSLYDN
260 270 280 290 300
KLGKVPQLAL QKVPNLKFLD LNKNPIRKIQ EGDFKNMLKL KELGINNMAE
310 320 330 340 350
LVSVDRNAME NLPELTKLEA TNNPKLSYIH RSAFRNVPTL ESLMLNNNAL
360 370 380 390 400
NSVYRGTVES LPNLREISIH SNPLRCDCVL HWMGSNQTSI RFMEPLSMFC
410 420 430 440 450
ALPPEYRGQP VKEALAQDPA GEQCLPMISQ DTFPSHLSLD IGMTISLDCR
460 470 480 490 500
ATAEPEPEIY WVTPLGHKVT LETLSDKYHL SGEGSLQIFN VQVEDSGRYT
510 520 530 540 550
CVAQNSEGAD TKVATLRVNG TLLDGTQALR LYVQQAESSS VLVSWKVSSS
560 570 580 590 600
VLASNLKWSS ATMKIDNPHI TYTARVPADV HEYNLTHLQP ATEYEVCLTV
610 620 630 640 650
SGLHQQAQRA CINVTTKGTS YSLTVTDQET SAALAAVMGS LFALISFASV
660 670 680 690 700
SVYAAKRFQR KNYRHSLKKY MQKTSSIPLN ELYPPLISLW EGDSEKEKEG
710
TAESKASQVD TSRSYYMW
Length:718
Mass (Da):80,035
Last modified:August 1, 1998 - v1
Checksum:iAEF840DCB28B8387
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014462 mRNA. Translation: BAA28530.1.
UniGeneiXl.24276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014462 mRNA. Translation: BAA28530.1.
UniGeneiXl.24276.

3D structure databases

ProteinModelPortaliO73675.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG052361.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
3.80.10.10. 3 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF07679. I-set. 1 hit.
PF13855. LRR_8. 4 hits.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00408. IGc2. 1 hit.
SM00369. LRR_TYP. 9 hits.
SM00082. LRRCT. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF49265. SSF49265. 1 hit.
SSF52058. SSF52058. 1 hit.
PROSITEiPS50853. FN3. 1 hit.
PS50835. IG_LIKE. 1 hit.
PS51450. LRR. 9 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning of XNLRR-1, a Xenopus homolog of mouse neuronal leucine-rich repeat protein expressed in the developing Xenopus nervous system."
    Hayata T., Uochi T., Asashima M.
    Gene 221:159-166(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO73675_XENLA
AccessioniPrimary (citable) accession number: O73675
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.