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Protein
Submitted name:

Melanocortin 5-receptor

Gene

MC5R

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Melanocortin 5-receptorImported
Gene namesi
Name:MC5RImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 59HelicalSequence analysisAdd BLAST24
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Transmembranei117 – 138HelicalSequence analysisAdd BLAST22
Transmembranei159 – 179HelicalSequence analysisAdd BLAST21
Transmembranei185 – 210HelicalSequence analysisAdd BLAST26
Transmembranei237 – 259HelicalSequence analysisAdd BLAST23
Transmembranei279 – 297HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 295G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST243

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000246927.
HOVERGENiHBG108148.
KOiK04203.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001908. Melancort_rcpt.
IPR000621. Melancort_rcpt_5.
IPR001671. Melcrt_ACTH_rcpt.
PANTHERiPTHR22750:SF50. PTHR22750:SF50. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00534. MCRFAMILY.
PR00535. MELNOCORTINR.
PR01063. MELNOCORTN5R.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O73671-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTSSQLYVS ELNLSAFGSN FTVPTVKSKS SPCEQVVIAA EVFLILGIVS
60 70 80 90 100
LLENILVICA IVKNKNLHSP MYFFVCSLAV ADMLVSVSNA WETITIYLIN
110 120 130 140 150
NRHIIMEDAF VRHIDNVFDS LICISVVASM CSLLAIAVDR YITIFYALRY
160 170 180 190 200
HNIMTVKRSG LIIACIWTFC TGCGIIFILY YESTYVIICL ITMFFTMLFL
210 220 230 240 250
MVSLYIHMFL LARTHVKKIA ALPGYNSVHQ RTSMKGAITL TMLLGIFIVC
260 270 280 290 300
WAPFFLHLIL MISCPQNLYC VCFMSHFNMY LILIMCNSVI DPLIYAFRSQ
310 320
EMRKTFKEII CCYSVRMVCG LSNKY
Length:325
Mass (Da):36,995
Last modified:August 1, 1998 - v1
Checksum:i35441907C71E4FA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF670718 mRNA. Translation: AHC02482.1.
AB012868 Genomic DNA. Translation: BAA25640.1.
RefSeqiNP_001026186.1. NM_001031015.1.
UniGeneiGga.14272.
Gga.52952.

Genome annotation databases

GeneIDi421047.
KEGGigga:421047.

Similar proteinsi

Entry informationi

Entry nameiO73671_CHICK
AccessioniPrimary (citable) accession number: O73671
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: August 30, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)