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Protein

Protein-serine/threonine kinase

Gene
N/A
Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei317Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-serine/threonine kinaseUniRule annotation (EC:2.7.11.-UniRule annotation)
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias

Structurei

3D structure databases

ProteinModelPortaliO73658.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 171RGSInterPro annotationAdd BLAST113
Domaini186 – 457Protein kinaseInterPro annotationAdd BLAST272
Domaini458 – 523AGC-kinase C-terminalInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0986. Eukaryota.
ENOG410YRQZ. LUCA.
HOGENOMiHOG000006742.
HOVERGENiHBG004532.
KOiK00909.

Family and domain databases

InterProiView protein in InterPro
IPR000961. AGC-kinase_C.
IPR000239. GPCR_kinase.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR016137. RGS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
PF00615. RGS. 1 hit.
PRINTSiPR00717. GPCRKINASE.
SMARTiView protein in SMART
SM00315. RGS. 1 hit.
SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS50132. RGS. 1 hit.

Sequencei

Sequence statusi: Complete.

O73658-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCDMGGLDNL VANTAYLKAQ GGDDKEMKKR RRSLSLPKPE QCVALRESIE
60 70 80 90 100
KDFTLLCERQ PIGKRLFRDF LANTPEFKLA AEFLDELYDW DLAEGAAKDK
110 120 130 140 150
ARQNIINKYC KPDSKTFLTF LSGEPAEKCK SVTDATFEEV MKNKVQDGVR
160 170 180 190 200
EFLKGKPFTE YQGSQYFDKF LQWKEYEKQP ISDKYFYEFR TLGKGGFGEV
210 220 230 240 250
CAVQVKNTGQ MYACKKLCKK RLKKKGGEKM ALLEKQILEK VNSLFLVNLA
260 270 280 290 300
YAYDTKTHLC LVMTLMNGGD LKYHIYNIGY DGKGVDKGIE MKRIIHYTAQ
310 320 330 340 350
ITTGILHLHD MDIIYRDMKP ENVLLDSQGQ CRLSDLGLAI EIAPGKTVTQ
360 370 380 390 400
MAGTGAYMAP EILSKTPYRT SVDWWALGCS IYEMVAGYTP FKGPESKKEK
410 420 430 440 450
VEKEEVQRRI LNEEPKWEHK CFDAPTKDVI QQFLKKKIDE RLGMRNNMED
460 470 480 490 500
PRKHEWFKSI NFPRLEAGLV DPPWVPKPNV VYAKDTGDIA EFSEIKGIEF
510 520 530 540 550
DAKDDKFFKE FSTGAVPIQW QQEMIETGLF DELNDPNRKE GAGGGDDEKK

SGTCALL
Length:557
Mass (Da):63,656
Last modified:August 1, 1998 - v1
Checksum:iA968753332E0065A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009568 mRNA. Translation: BAA25670.1.
RefSeqiNP_001098131.1. NM_001104661.1.
UniGeneiOla.77.

Genome annotation databases

GeneIDi100049187.
KEGGiola:100049187.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO73658_ORYLA
AccessioniPrimary (citable) accession number: O73658
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: July 5, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)