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Protein

POU domain protein

Gene

Brain-4 gene

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Brain-4 geneImported
Synonyms:POU3F4Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaIguanidaePolychrotinaeAnolis
Proteomesi
  • UP000001646 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi28377.ENSACAP00000014247.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini175 – 24975POU-specificInterPro annotationAdd
BLAST
Domaini265 – 32561Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOGENOMiHOG000116303.
HOVERGENiHBG053120.
KOiK09365.
OrthoDBiEOG7DJSMG.
TreeFamiTF316413.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR016362. TF_POU_3.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PIRSFiPIRSF002629. Transcription_factor_POU. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O73629-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAASNPYS LLVHAEAAPG MPQGGPFRGH HQKLLQSDYL QGNGHPLGHH
60 70 80 90 100
WVTSLSDAGP WASSLAEQPD IKPGREDLQQ LGGLLHHRSP PHHHHGNGGV
110 120 130 140 150
GGGAGHLQSA WSSSPNPPGN VYSQGGFGVG AMLEHGGLSP PPTAANSVPN
160 170 180 190 200
NNVATALLPE PHDPLNSHPG DPSDEETPTS DELEQFAKQF KQRRIKLGFT
210 220 230 240 250
QADVGLALGT LYGNVFSQTT ICRFEALQLS FKNMCKLKPL LNKWLEEADS
260 270 280 290 300
STGSPTGLDK IAAQGRKRKK RTSIEVSVKG VLETHFLKCP KPAAQEIAAL
310 320 330 340 350
ADSLQLEKEV VRVWFCNRRQ KEKRMTPPGE NNGGAPAHEA YGAGGGGGPK

ADCRDL
Length:356
Mass (Da):37,910
Last modified:August 1, 1998 - v1
Checksum:i3C34FA6250AE5FD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001870 Genomic DNA. Translation: BAA28667.1.
RefSeqiXP_003223421.1. XM_003223373.2.

Genome annotation databases

EnsembliENSACAT00000014539; ENSACAP00000014247; ENSACAG00000014539.
GeneIDi100565914.
KEGGiacs:100565914.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001870 Genomic DNA. Translation: BAA28667.1.
RefSeqiXP_003223421.1. XM_003223373.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000014247.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSACAT00000014539; ENSACAP00000014247; ENSACAG00000014539.
GeneIDi100565914.
KEGGiacs:100565914.

Organism-specific databases

CTDi5456.

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOGENOMiHOG000116303.
HOVERGENiHBG053120.
KOiK09365.
OrthoDBiEOG7DJSMG.
TreeFamiTF316413.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR016362. TF_POU_3.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PIRSFiPIRSF002629. Transcription_factor_POU. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide compositional constraints on genomes generate alanine-, glycine-, and proline-rich structures in transcription factors."
    Nakachi Y., Hayakawa T., Oota H., Sumiyama K., Wang L., Ueda S.
    Mol. Biol. Evol. 14:1042-1049(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The Genome Sequence of Anolis carolinensis (Green Anole Lizard)."
    The Genome Sequencing Platform
    Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J., Lander E.S., Lindblad-Toh K.
    Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JBL SC #1Imported.
  4. Ensembl
    Submitted (MAR-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiO73629_ANOCA
AccessioniPrimary (citable) accession number: O73629
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.