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Protein

POU domain protein

Gene

Brain-4 gene

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi267 – 326HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Brain-4 geneImported
Synonyms:POU3F4Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
Proteomesi
  • UP000001646 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSACAG00000014539

Interactioni

Protein-protein interaction databases

STRINGi28377.ENSACAP00000014247

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini175 – 249POU-specificInterPro annotationAdd BLAST75
Domaini265 – 325HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802 Eukaryota
ENOG410XQ7X LUCA
GeneTreeiENSGT00760000118935
HOGENOMiHOG000116303
HOVERGENiHBG053120
KOiK09365
OrthoDBiEOG091G0U0S
TreeFamiTF316413

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
IPR013847 POU
IPR000327 POU_dom
IPR016362 TF_POU_3
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00157 Pou, 1 hit
PIRSFiPIRSF002629 Transcription_factor_POU, 1 hit
PRINTSiPR00028 POUDOMAIN
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00352 POU, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00035 POU_1, 1 hit
PS00465 POU_2, 1 hit
PS51179 POU_3, 1 hit

Sequencei

Sequence statusi: Complete.

O73629-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAASNPYS LLVHAEAAPG MPQGGPFRGH HQKLLQSDYL QGNGHPLGHH
60 70 80 90 100
WVTSLSDAGP WASSLAEQPD IKPGREDLQQ LGGLLHHRSP PHHHHGNGGV
110 120 130 140 150
GGGAGHLQSA WSSSPNPPGN VYSQGGFGVG AMLEHGGLSP PPTAANSVPN
160 170 180 190 200
NNVATALLPE PHDPLNSHPG DPSDEETPTS DELEQFAKQF KQRRIKLGFT
210 220 230 240 250
QADVGLALGT LYGNVFSQTT ICRFEALQLS FKNMCKLKPL LNKWLEEADS
260 270 280 290 300
STGSPTGLDK IAAQGRKRKK RTSIEVSVKG VLETHFLKCP KPAAQEIAAL
310 320 330 340 350
ADSLQLEKEV VRVWFCNRRQ KEKRMTPPGE NNGGAPAHEA YGAGGGGGPK

ADCRDL
Length:356
Mass (Da):37,910
Last modified:August 1, 1998 - v1
Checksum:i3C34FA6250AE5FD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001870 Genomic DNA Translation: BAA28667.1
RefSeqiXP_003223421.1, XM_003223373.2

Genome annotation databases

EnsembliENSACAT00000014539; ENSACAP00000014247; ENSACAG00000014539
GeneIDi100565914
KEGGiacs:100565914

Similar proteinsi

Entry informationi

Entry nameiO73629_ANOCA
AccessioniPrimary (citable) accession number: O73629
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health