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Protein

POU domain protein

Gene

Brain-1 gene

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi360 – 419HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Brain-1 geneImported
Synonyms:pou3f3Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
Proteomesi
  • UP000001646 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSACAG00000008907.

Interactioni

Protein-protein interaction databases

STRINGi28377.ENSACAP00000020802.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini268 – 342POU-specificInterPro annotationAdd BLAST75
Domaini358 – 418HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOVERGENiHBG053120.
OMAiGMTGSPQ.
OrthoDBiEOG091G0U0S.
TreeFamiTF316413.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom_sf.
IPR013847. POU.
IPR000327. POU_dom.
IPR016362. TF_POU_3.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PIRSFiPIRSF002629. Transcription_factor_POU. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

O73627-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAASNPYL PGNSLLSAAG AIVHSDAAAG GMQPGSVAVT SVAGGGGGGA
60 70 80 90 100
GGGGNGGNNN ANNGYRGDPS SVKMVQSDFM VQSNGGHMLS HAHQWVTALP
110 120 130 140 150
HAAAAAAAAA AAAAAEAGSP WSSMSGSPQQ QQQQQQQQQD VKGGGGGRED
160 170 180 190 200
LLHHRPPHLG PPPPHQGHWG SMAGQQQQQQ QQQQAPLLYS QPGGFTVNGM
210 220 230 240 250
LSPPPGSQAL GVHPGLVRGD TPELGDHPGH HHHHHQQHHH HPHAHHGGGG
260 270 280 290 300
GGGGGGGGLN SHDPHSDEDT PTSDDLEQFA KQFKQRRIKL GFTQADVGLA
310 320 330 340 350
LGTLYGNVFS QTTICRFEAL QLSFKNMCKL KPLLNKWLEE ADSSTGSPTS
360 370 380 390 400
IDKIAAQGRK RKKRTSIEVS VKGALESHFL KCPKPSAQEI TSLADSLQLE
410 420 430 440 450
KEVVRVWFCN RRQKEKRMTP PGIPQQAPDD VYSQVGNVSA DTPPPHHGLQ

GGVQ
Length:454
Mass (Da):47,407
Last modified:August 1, 1998 - v1
Checksum:i9771C228F0390D27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001868 Genomic DNA. Translation: BAA28665.1.
RefSeqiXP_003224330.1. XM_003224282.3.

Genome annotation databases

EnsembliENSACAT00000008913; ENSACAP00000020802; ENSACAG00000008907.
GeneIDi100568190.

Similar proteinsi

Entry informationi

Entry nameiO73627_ANOCA
AccessioniPrimary (citable) accession number: O73627
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 22, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported