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Protein

POU domain protein

Gene

Brain-1 gene

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Brain-1 geneImported
Synonyms:POU3F3Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaIguanidaePolychrotinaeAnolis
Proteomesi
  • UP000001646 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSACAG00000008907.

Interactioni

Protein-protein interaction databases

STRINGi28377.ENSACAP00000020802.

Structurei

3D structure databases

SMRiO73627. Positions 274-420.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini268 – 34275POU-specificInterPro annotationAdd
BLAST
Domaini358 – 41861Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOVERGENiHBG053120.
KOiK09365.
OMAiPELEHGG.
OrthoDBiEOG091G0U0S.
TreeFamiTF316413.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR016362. TF_POU_3.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PIRSFiPIRSF002629. Transcription_factor_POU. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O73627-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAASNPYL PGNSLLSAAG AIVHSDAAAG GMQPGSVAVT SVAGGGGGGA
60 70 80 90 100
GGGGNGGNNN ANNGYRGDPS SVKMVQSDFM VQSNGGHMLS HAHQWVTALP
110 120 130 140 150
HAAAAAAAAA AAAAAEAGSP WSSMSGSPQQ QQQQQQQQQD VKGGGGGRED
160 170 180 190 200
LLHHRPPHLG PPPPHQGHWG SMAGQQQQQQ QQQQAPLLYS QPGGFTVNGM
210 220 230 240 250
LSPPPGSQAL GVHPGLVRGD TPELGDHPGH HHHHHQQHHH HPHAHHGGGG
260 270 280 290 300
GGGGGGGGLN SHDPHSDEDT PTSDDLEQFA KQFKQRRIKL GFTQADVGLA
310 320 330 340 350
LGTLYGNVFS QTTICRFEAL QLSFKNMCKL KPLLNKWLEE ADSSTGSPTS
360 370 380 390 400
IDKIAAQGRK RKKRTSIEVS VKGALESHFL KCPKPSAQEI TSLADSLQLE
410 420 430 440 450
KEVVRVWFCN RRQKEKRMTP PGIPQQAPDD VYSQVGNVSA DTPPPHHGLQ

GGVQ
Length:454
Mass (Da):47,407
Last modified:August 1, 1998 - v1
Checksum:i9771C228F0390D27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001868 Genomic DNA. Translation: BAA28665.1.
RefSeqiXP_003224330.1. XM_003224282.3.

Genome annotation databases

EnsembliENSACAT00000008913; ENSACAP00000020802; ENSACAG00000008907.
GeneIDi100568190.
KEGGiacs:100568190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001868 Genomic DNA. Translation: BAA28665.1.
RefSeqiXP_003224330.1. XM_003224282.3.

3D structure databases

SMRiO73627. Positions 274-420.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000020802.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSACAT00000008913; ENSACAP00000020802; ENSACAG00000008907.
GeneIDi100568190.
KEGGiacs:100568190.

Organism-specific databases

CTDi5455.

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOVERGENiHBG053120.
KOiK09365.
OMAiPELEHGG.
OrthoDBiEOG091G0U0S.
TreeFamiTF316413.

Gene expression databases

BgeeiENSACAG00000008907.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR016362. TF_POU_3.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PIRSFiPIRSF002629. Transcription_factor_POU. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO73627_ANOCA
AccessioniPrimary (citable) accession number: O73627
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.