GAAI

Functionⁱ

GO - Molecular functionⁱ

carbohydrate binding Source: InterPro
hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

carbohydrate metabolic process Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	GlycosidaseUniRule annotation, Hydrolase

Molecular function

GlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GH31. Glycoside Hydrolase Family 31.

CAZyⁱ

GH31. Glycoside Hydrolase Family 31.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Acid alpha-glucosidaseImported
Gene namesⁱ	Name:GAAIImported Synonyms:gaa1Imported
Organismⁱ	Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)Imported
Taxonomic identifierⁱ	93934 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Sauropsida › Sauria › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Perdicinae › Coturnix

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	41 – 62	HelicalSequence analysisAdd BLAST		22

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O73626.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	76 – 129	P-type (trefoil)InterPro annotationAdd BLAST		54

Sequence similaritiesⁱ

Belongs to the glycosyl hydrolase 31 family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENⁱ	HBG006297.

HOVERGENⁱ

HBG006297.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00111. Trefoil. 1 hit.
InterProⁱ	View protein in InterPro IPR031727. Gal_mutarotase_N. IPR011013. Gal_mutarotase_SF_dom. IPR000322. Glyco_hydro_31. IPR030458. Glyco_hydro_31_AS. IPR030459. Glyco_hydro_31_CS. IPR025887. Glyco_hydro_31_N_dom. IPR017853. Glycoside_hydrolase_SF. IPR000519. P_trefoil_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13802. Gal_mutarotas_2. 1 hit. PF01055. Glyco_hydro_31. 1 hit. PF16863. NtCtMGAM_N. 1 hit. PF00088. Trefoil. 1 hit.
SMARTⁱ	View protein in SMART SM00018. PD. 1 hit.
SUPFAMⁱ	SSF51445. SSF51445. 2 hits. SSF74650. SSF74650. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00129. GLYCOSYL_HYDROL_F31_1. 1 hit. PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit. PS51448. P_TREFOIL_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

O73626-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRSYQKLRTA VPQLVLSQEE EEEEEDATTP TPAGRSKLAP WWVGSGLLIT 
        60         70         80         90        100
AVLLSTITVW VLRQVSRGWH GPAPPAQCHL VPESHRYDCY PERNVVVTQE 
       110        120        130        140        150
LCESRGCCFI QTLPAVGGKR GVPWCFYPPD FPSYVVQSLN QTVLGMTGLL 
       160        170        180        190        200
VRREKAYYPK DIQMLRMDVE FQTNTRLHIK ITDAANPRYE VPLEVPRVTK 
       210        220        230        240        250
RAENPIYSLE ISQDPFGVLL RRQGTGTVLL NTTVAPLIFA DQFLQISTTL 
       260        270        280        290        300
PSRFLYGLGE HRSTLLHSLD WNTLTLWARD VAPTESFNLY GAHPFYLLME 
       310        320        330        340        350
EGGDAHGVFL LNSNAMEVAL QPAPGLTWRT IGGVLDFYIF LGPDPNMVIQ 
       360        370        380        390        400
QYQEVIGFPA MPPLWALGFH LCRWGYGSSN ETWQTAKAMR NFQIPQDAQW 
       410        420        430        440        450
NDIDYMDGYR DFTFDPQKFA SLPSLVEDLH KHGQHYVIIL DPGISSTSPR 
       460        470        480        490        500
GSYWPFDEGL RRGLFLNTTQ GQTLIGQVWP GYTAYPDFSN TDTHQWWLEN 
       510        520        530        540        550
LQRFHTHVPF DGLWIDMNEP SNFMDGSEEG CPPGELDSPP YTPAVLGNSL 
       560        570        580        590        600
TAKTVCASAE QNASVHYNLH NLYGLKEAEA TASALIRIRG KRPFVISRST 
       610        620        630        640        650
FPSQGRYSGH WLGDNRSQWK DMYYSIPGML SFSLFGIPLV GADICGFSGS 
       660        670        680        690        700
TSEELCTRWM QLGAFYPFSR NHNNQNEKAQ DPTAFSPSAR TAMKDALLTR 
       710        720        730        740        750
YSLLPFLYTL FHRAHLQGET VARPLFFEFP WDVATYGLDR QFLWGQSLLV 
       760        770        780        790        800
TPVLEPGADS VLGYFPQGVW YDFYTGSSVN SSGEMLKLSA PLDHLNLHLR 
       810        820        830        840        850
EGSILPTQKP GITSKATRGN PLHLIVALST RATAWGDLFW DDGESLDTFE 
       860        870        880        890        900
QGNYSYLVFN ATENIFTSNV LHASTEATDV TIDAVSFYGV QEPPSKVLLD 
       910        920        930 
GQEKPFSYLD NQVLTVSGLG LVLSQGFSLQ WL

Length:932

Mass (Da):104,689

Last modified:August 1, 1998 - v1

Checksum:ⁱB62E182F03DE3F61

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB000967 mRNA. Translation: BAA25884.1. AB081289 Genomic DNA. Translation: BAC15595.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AB000967 mRNA. Translation: BAA25884.1.
AB081289 Genomic DNA. Translation: BAC15595.1.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
O73626	UPI0007779CE1 UPI000776F9AE UPI00077753E4 UPI000549DB7A UPI000B3D8B7E G1MUL5 A0A1D5P2Y5 UPI000739D52F	Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) Meleagris gallopavo (Common turkey) Numida meleagris (Helmeted guineafowl) (Phasianus meleagris) Gallus gallus (Chicken)	932	UniRef90_O73626	Cluster: Acid alpha-glucosidase	9

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
O73626	G1N308 UPI000549CB12 UPI0007DCB3B6 UPI00071A421E UPI00077108B2 UPI0008F4E9CA UPI000B4D804D UPI000B4CC9B0 UPI0006B7292F U3KHM3 +38	Meleagris gallopavo (Common turkey) Cynoglossus semilaevis (Tongue sole) Sturnus vulgaris (Starling) Parus major (Great tit) Lonchura striata domestica (Bengalese finch) Zonotrichia albicollis (White-throated sparrow) Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis) Taeniopygia guttata (Zebra finch) (Poephila guttata) Boleophthalmus pectinirostris (Great blue-spotted mudskipper) (Gobius pectinirostris) Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus) And more	762	UniRef50_G1N308	Cluster: Glucosidase alpha, acid	49

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB000967 mRNA. Translation: BAA25884.1. AB081289 Genomic DNA. Translation: BAC15595.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AB000967 mRNA. Translation: BAA25884.1.
AB081289 Genomic DNA. Translation: BAC15595.1.

3D structure databases

ProteinModelPortalⁱ	O73626.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GH31. Glycoside Hydrolase Family 31.

CAZyⁱ

GH31. Glycoside Hydrolase Family 31.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

HOVERGENⁱ	HBG006297.

HOVERGENⁱ

HBG006297.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00111. Trefoil. 1 hit.
InterProⁱ	View protein in InterPro IPR031727. Gal_mutarotase_N. IPR011013. Gal_mutarotase_SF_dom. IPR000322. Glyco_hydro_31. IPR030458. Glyco_hydro_31_AS. IPR030459. Glyco_hydro_31_CS. IPR025887. Glyco_hydro_31_N_dom. IPR017853. Glycoside_hydrolase_SF. IPR000519. P_trefoil_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13802. Gal_mutarotas_2. 1 hit. PF01055. Glyco_hydro_31. 1 hit. PF16863. NtCtMGAM_N. 1 hit. PF00088. Trefoil. 1 hit.
SMARTⁱ	View protein in SMART SM00018. PD. 1 hit.
SUPFAMⁱ	SSF51445. SSF51445. 2 hits. SSF74650. SSF74650. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00129. GLYCOSYL_HYDROL_F31_1. 1 hit. PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit. PS51448. P_TREFOIL_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O73626_COTJA
Accessionⁱ	O73626Primary (citable) accession number: O73626
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	August 1, 1998
	Last sequence update:	August 1, 1998
	Last modified:	August 30, 2017
	This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

UniProtKB - O73626 (O73626_COTJA)

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Acid alpha-glucosidase

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Protein family/group databases

Names & Taxonomyⁱ

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O73626 (O73626_COTJA)

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Acid alpha-glucosidase

GAAI

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ