ID   MCES_FOWPV              Reviewed;         289 AA.
AC   O72908;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   16-JUN-2009, entry version 42.
DE   RecName: Full=mRNA-capping enzyme small subunit;
DE   AltName: Full=mRNA (guanine-N(7)-)-methyltransferase;
DE            EC=2.1.1.56;
DE   AltName: Full=mRNA cap methyltransferase;
GN   OrderedLocusNames=FPV051; ORFNames=FP-D12, FPD12;
OS   Fowlpox virus (FPV).
OC   Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae;
OC   Avipoxvirus.
OX   NCBI_TaxID=10261;
OH   NCBI_TaxID=7742; Vertebrata.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FP-9 / Isolate HP-440;
RA   Skinner M.A.;
RL   Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=91108382; PubMed=2177083;
RA   Binns M.M., Britton B.S., Mason C., Boursnell M.E.G.;
RT   "Analysis of the fowlpox virus genome region corresponding to the
RT   vaccinia virus D6 to A1 region: location of, and variation in, non-
RT   essential genes in poxviruses.";
RL   J. Gen. Virol. 71:2873-2881(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=20193820; PubMed=10729156;
RX   DOI=10.1128/JVI.74.8.3815-3831.2000;
RA   Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
RT   "The genome of fowlpox virus.";
RL   J. Virol. 74:3815-3831(2000).
CC   -!- FUNCTION: Catalyzes the last reaction in the mRNA cap formation
CC       pathway.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + G(5')pppR-RNA = S-
CC       adenosyl-L-homocysteine + m(7)G(5')pppR-RNA.
CC   -!- SUBUNIT: Heterodimer of a large and a small subunit.
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DR   EMBL; AJ005163; CAA06402.1; -; Genomic_DNA.
DR   EMBL; AF198100; AAF44395.1; -; Genomic_DNA.
DR   PIR; S42252; S42252.
DR   RefSeq; NP_039014.1; -.
DR   GeneID; 1486599; -.
DR   BRENDA; 2.1.1.56; 288568.
DR   GO; GO:0004482; F:mRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
DR   GO; GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.
DR   InterPro; IPR005009; Pox_mRNA-cap.
DR   Pfam; PF03341; Pox_mRNA-cap; 1.
DR   ProDom; PD009934; Pox_mRNA-cap; 1.
PE   4: Predicted;
KW   Methyltransferase; mRNA capping; mRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    289       mRNA-capping enzyme small subunit.
FT                                /FTId=PRO_0000210139.
SQ   SEQUENCE   289 AA;  33867 MW;  ADCEFC32AA71B131 CRC64;
     MNTDRITAFI KNGISARMPF YDTLPDMDLV FGKNHLPSLE YGANYFLQLS KINDINRLST
     EMLSLYTHDL NKESDISKLF EPYNIKTIKS YGRSIQADAV VVDLRPSNSL YKNEHPYYKS
     NNYLKENNLY ICDYTMITFE IYRPIFELST EKTCIIKVPT LFGKTIVNAV RVYCSLFRYV
     KLYKLSADSW LKDSAIIVCQ QPHAANINKF ITYIRKVTKS QTWLDSNNVN FILIHDSVER
     VFIEKFLSFS YKIYESLYYV HSLLYSSMTS DLQSLDNEYQ KKLIKLLRG
//