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Protein

Replication enhancer

Gene

AC3

Organism
Cotton leaf curl Alabad virus-[802a]
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Enhances infectivity and symptom expression.UniRule annotation
Increases viral DNA accumulation.UniRule annotation

GO - Biological processi

Keywordsi

Biological processHost-virus interactionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Replication enhancerUniRule annotation
Short name:
REnUniRule annotation
Gene namesi
Name:AC3Imported
OrganismiCotton leaf curl Alabad virus-[802a]Imported
Taxonomic identifieri222457 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus
Proteomesi
  • UP000203502 Componenti: Genome

Interactioni

Subunit structurei

Homooligomer. Interacts with the replication-associated protein (REP). Interacts with host proliferating cell nuclear antigen (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), and may thereby deregulate the host cell cycle. Oligomerization and interaction with PCNA are necessary for optimal replication enhancement.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the geminiviridae replication enhancer protein family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR000657 Gemini_AL3
PfamiView protein in Pfam
PF01407 Gemini_AL3, 1 hit
PRINTSiPR00231 GEMCOATAL3
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001172 Gemini_AL3, 1 hit

Sequencei

Sequence statusi: Complete.

O72717-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSRTGERIT AAHSTNGVFI WEVPNPLYFK ILSHDNRPFT TNMDIITMRI
60 70 80 90 100
QFNYNLRKAL GVHKCFLTFR IWTTLYPPTG LFLRVFKTQV LKYLNNLGVI
110 120 130
SLNLVIKAVE HVLYNVINQT MYVDQYSDIK FKLY
Length:134
Mass (Da):15,782
Last modified:August 1, 1998 - v1
Checksum:iDA91C678579B87FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002455 Genomic DNA Translation: CAA05460.1
RefSeqiNP_795359.1, NC_004582.1

Genome annotation databases

GeneIDi1482982
KEGGivg:1482982

Similar proteinsi

Entry informationi

Entry nameiO72717_9GEMI
AccessioniPrimary (citable) accession number: O72717
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health