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Protein

Protein VP2

Gene

ORF3

Organism
Canine calicivirus (strain 48) (CaCV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF3
OrganismiCanine calicivirus (strain 48) (CaCV)
Taxonomic identifieri292348 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeVesivirusunclassified Vesivirus
Virus hostiCanis familiaris (Dog) (Canis lupus familiaris) [TaxID: 9615]

Subcellular locationi

  1. Virion
  2. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 133133Protein VP2PRO_0000100121Add
BLAST

Interactioni

Subunit structurei

May interact with capsid protein.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the vesivirus VP2 protein family.Curated

Family and domain databases

InterProiIPR007996. Vesivirus_VP2.
[Graphical view]
PfamiPF05332. DUF743. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O72121-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVAAAITAG ASAAQAGTGL IGSIANAIHE GTRLKLQGQA LGAQIKFQEA
60 70 80 90 100
ENKFNRDRFE FDKLNTERWF RLAKEQQSLV YELNTKGPAM RAQAMMDAGF
110 120 130
RNNLYSNGNQ LTFNEVREAQ LSAEKRFYNP SLF
Length:133
Mass (Da):14,780
Last modified:August 1, 1998 - v1
Checksum:i099724FE3C3E6267
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053720 Genomic RNA. Translation: AAC16447.1.
AB070225 Genomic RNA. Translation: BAB83603.1.
RefSeqiNP_777375.1. NC_004542.1.

Genome annotation databases

GeneIDi956317.
KEGGivg:956317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053720 Genomic RNA. Translation: AAC16447.1.
AB070225 Genomic RNA. Translation: BAB83603.1.
RefSeqiNP_777375.1. NC_004542.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi956317.
KEGGivg:956317.

Family and domain databases

InterProiIPR007996. Vesivirus_VP2.
[Graphical view]
PfamiPF05332. DUF743. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Organization of the canine calicivirus genome from the RNA polymerase gene to the poly(A) tail."
    Roerink F., Hashimoto M., Tohya Y., Mochizuki M.
    J. Gen. Virol. 80:929-935(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Complete nucleotide sequence, genome organization and phylogenic analysis of the canine calicivirus."
    Matsuura Y., Tohya Y., Nakamura K., Shimojima M., Roerink F., Mochizuki M., Takase K., Akashi H., Sugimura T.
    Virus Genes 25:67-73(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVP2_CACV4
AccessioniPrimary (citable) accession number: O72121
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: August 1, 1998
Last modified: April 29, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.