O72121 (VP2_CACV4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein VP2

Alternative name(s):
Minor capsid protein

Gene names

ORF Names:

ORF3

Organism

Canine calicivirus (strain 48) (CaCV)

Taxonomic identifier

292348 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Caliciviridae › unclassified Caliciviridae › Canine calicivirus

Virus host

Canis familiaris (Dog) (Canis lupus familiaris) [TaxID: 9615]

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus By similarity.
Subunit structure	May interact with capsid protein By similarity.
Subcellular location	Virion. Host cytoplasm By similarity.
Miscellaneous	Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA encoding for VP1 and VP2.
Sequence similarities	Belongs to the vesivirus VP2 protein family.

Ontologies

Keywords
Cellular component	Host cytoplasm Virion
Gene Ontology (GO)
Cellular_component	host cell cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	Protein VP2		PRO_0000100121

Sequences

	Sequence		Length	Mass (Da)
	O72121 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 099724FE3C3E6267	FASTA	133	14,780
	10 20 30 40 50 60 MSVAAAITAG ASAAQAGTGL IGSIANAIHE GTRLKLQGQA LGAQIKFQEA ENKFNRDRFE 70 80 90 100 110 120 FDKLNTERWF RLAKEQQSLV YELNTKGPAM RAQAMMDAGF RNNLYSNGNQ LTFNEVREAQ 130 LSAEKRFYNP SLF

References

[1]	"Organization of the canine calicivirus genome from the RNA polymerase gene to the poly(A) tail." Roerink F., Hashimoto M., Tohya Y., Mochizuki M. J. Gen. Virol. 80:929-935(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"Complete nucleotide sequence, genome organization and phylogenic analysis of the canine calicivirus." Matsuura Y., Tohya Y., Nakamura K., Shimojima M., Roerink F., Mochizuki M., Takase K., Akashi H., Sugimura T. Virus Genes 25:67-73(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF053720 Genomic RNA. Translation: AAC16447.1. AB070225 Genomic RNA. Translation: BAB83603.1.
RefSeq	NP_777375.1. NC_004542.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	956317.
Family and domain databases
InterPro	IPR007996. Vesivirus_VP2. [Graphical view]
Pfam	PF05332. DUF743. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VP2_CACV4

Accession

Primary (citable) accession number: O72121

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 9, 2004
Last sequence update:	August 1, 1998
Last modified:	April 3, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program