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Protein

Movement protein Hsp70h

Gene

ORF4

Organism
Grapevine leafroll-associated virus 3 (isolate United States/NY1) (GLRaV-3) (Grapevine leafroll-associated closterovirus (isolate 109))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Two movement proteins, p6, Hsp70h and three structural proteins, CP, CPm, and P64 are essential for cell-cell movement. Also plays a role in virion formation. Together with CPm and p64, encapsidates the 5'-terminal portion of the viral genome (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Movement protein Hsp70h
Alternative name(s):
Heat shock protein 70 homolog
Short name:
Hsp70h
Gene namesi
ORF Names:ORF4
OrganismiGrapevine leafroll-associated virus 3 (isolate United States/NY1) (GLRaV-3) (Grapevine leafroll-associated closterovirus (isolate 109))
Taxonomic identifieri651354 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageClosteroviridaeAmpelovirus
Virus hostiVitis vinifera (Grape) [TaxID: 29760]
Proteomesi
  • UP000006707 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

  • virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Movement protein Hsp70hPRO_0000402534Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO71192.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

KOiK04044.

Family and domain databases

Gene3Di2.60.34.10. 1 hit.
InterProiIPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.

Sequencei

Sequence statusi: Complete.

O71192-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVGIDFGTT FSTICFSPSG VSGCTPVAGS VYVETQIFIP EGSSTYLIGK
60 70 80 90 100
AAGKAYRDGV EGRLYVNPKR WAGVTRDNVE RYVEKLKPTY TVKIDSGGAL
110 120 130 140 150
LIGGLGSGPD TLLRVVDVIC LFLRALILEC ERYTSTTVTA AVVTVPADYN
160 170 180 190 200
SFKRSFVVEA LKGLGIPVRG VVNEPTAAAL YSLAKSRVED LLLAVFDFGG
210 220 230 240 250
GTFDVSFVKK KGNILCVIFS VGDNFLGGRD IDRAIVEVIK QKIKGKASDA
260 270 280 290 300
KLGIFVSSMK EDLSNNNAIT QHLIPVEGGV EVVDLTSDEL DAIVAPFSAR
310 320 330 340 350
AVEVFKTGLD NFYPDPVIAV MTGGSSALVK VRSDVANLPQ ISKVVFDSTD
360 370 380 390 400
FRCSVACGAK VYCDTLAGNS GLRLVDTLTN TLTDEVVGLQ PVVIFPKGSP
410 420 430 440 450
IPCSYTHRYT VGGGDVVYGI FEGENNRAFL NEPTFRGVSK RRGDPVETDV
460 470 480 490 500
AQFNLSTDGT VSVIVNGEEV KNEYLVPGTT NVLDSLVYKS GREDLEAKAI
510 520 530 540
PEYLTTLNIL HDKAFTRRNL GNKDKGFSDL RIEENFLKSA VDTDTILNG
Length:549
Mass (Da):59,013
Last modified:August 1, 1998 - v1
Checksum:iDC35C6A811D61480
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037268 Genomic RNA. Translation: AAC40708.1.
RefSeqiNP_813799.1. NC_004667.1.

Genome annotation databases

GeneIDi1444470.
KEGGivg:1444470.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037268 Genomic RNA. Translation: AAC40708.1.
RefSeqiNP_813799.1. NC_004667.1.

3D structure databases

ProteinModelPortaliO71192.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1444470.
KEGGivg:1444470.

Phylogenomic databases

KOiK04044.

Family and domain databases

Gene3Di2.60.34.10. 1 hit.
InterProiIPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMVP1_GLRV3
AccessioniPrimary (citable) accession number: O71192
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: August 1, 1998
Last modified: June 24, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.