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O71155 (CAPSD_DSDNV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 31, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Capsid protein VP1
Alternative name(s):
Coat protein VP1
Structural protein VP1
Gene names
Name:VP
OrganismDiatraea saccharalis densovirus (DsDNV) [Complete proteome]
Taxonomic identifier72003 [NCBI]
Taxonomic lineageVirusesssDNA virusesParvoviridaeDensovirinaeDensovirus
Virus hostDiatraea saccharalis (sugarcane borer) [TaxID: 40085]

Protein attributes

Sequence length809 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of size variants of the capsid proteins, which differ in the N-terminushe capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis By similarity.

Subcellular location

Virion Potential.

Domain

The N-terminus of VP1 is sequestered within the mature capsid. It contains a phospholipase A2-like region and putative nuclear localization signals.

Alternative products

This entry describes 4 isoforms produced by alternative initiation. [Align] [Select]
Isoform VP1 (identifier: O71155-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform VP2 (identifier: O71155-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-277: Missing.
Isoform VP3 (identifier: O71155-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-322: Missing.
Isoform VP4 (identifier: O71155-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-373: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 809809Capsid protein VP1
PRO_0000039447

Natural variations

Alternative sequence1 – 373373Missing in isoform VP4.
VSP_018949
Alternative sequence1 – 322322Missing in isoform VP3.
VSP_018948
Alternative sequence1 – 277277Missing in isoform VP2.
VSP_018947

Sequences

Sequence LengthMass (Da)Tools
Isoform VP1 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: B07D809018C1C140

FASTA80987,961
        10         20         30         40         50         60 
MSFYARALTH RARPGYRIIP ENTVTEDIEL GAIGEETPLL SEGIITAAEE TAAVGLPELG 

        70         80         90        100        110        120 
VGAVGAVGTH ADVLYRNRNA FKSVLTGNYT DLKGNPLKQR NAISEKTKQL GKQIFQGDFN 

       130        140        150        160        170        180 
RAFPDNLKLE TEQEKTDLLR YYNHNRRLAG LSEAYPQGKG YAYAKSQKVL EAEKRGLTVP 

       190        200        210        220        230        240 
GYKYLGPGNS LNRGPPTNEI DADAKEHDEA YSQSKTAQEV SKADNTFVNK ALDHVVNAIN 

       250        260        270        280        290        300 
LKESPSNTVG AIIGATGIGT KQAIEKHTGV IYPSVSGMSR EINPKYLNSW SDWIKENKPN 

       310        320        330        340        350        360 
NFAGIQLPED FYTEEQTLSD SPMSESTKRK ADTPAEETPS KKGAHNTDSS SQSADPQNPS 

       370        380        390        400        410        420 
SSGATTDLDV TMAMSLPGTG SGTSSGGGNT TGQEIYEIPR PFTNFGKKLS TYTKSHKFMI 

       430        440        450        460        470        480 
FGLANNVIAE TGTTGNLHRL LTTCLAEIPW QKIPLYMNQS EFDLLPPGSR IVECNVKVIF 

       490        500        510        520        530        540 
RSNRIAFETS STATKQATLN QISNLQTAVG LNKLGWGIDR SFTAFQSDQP MIPTASAPPK 

       550        560        570        580        590        600 
YASVSGANGY RGMIADYYGA DSNNDIAFGN AGNYPHHQVG SFTFLQNYYC MYIQTERGTG 

       610        620        630        640        650        660 
GWPCLAEHFQ QYDSKTVNNQ CLLDVSYKPQ MGMIKPPLNY NIIGFPTNKG AISIGENLTA 

       670        680        690        700        710        720 
MRSANVSGPE IATQQVSETS NNRIHNFPAT FFDIYADIEK SQRLNKGPWG FEHPQIQPSI 

       730        740        750        760        770        780 
HIGMQAVPAL TTGALLVNSS PLNSWTDSMG YVDVIASCTV MESQPTHFPY ATSANTNPGN 

       790        800 
TVYRNNINVN SLTSAFNGLY GNAATLGSL 

« Hide

Isoform VP2 [UniParc].

Checksum: 23770477B2A27CF5
Show »

FASTA53257,976
Isoform VP3 [UniParc].

Checksum: 641DECD0FFFD8568
Show »

FASTA48752,660
Isoform VP4 [UniParc].

Checksum: D4990132FE5CE3DF
Show »

FASTA43647,424

References

[1]"Complete nucleotide sequence and genome organization of an infectious clone of Diatraea saccharalis densovirus (DsDNV)."
Boublik Y., Kouassi K.N., Cavallaro C., Bergoin M.
Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF036333 Genomic DNA. Translation: AAC18002.1.
AF036333 Genomic DNA. Translation: AAC18001.1.
RefSeqNP_046815.1. NC_001899.1.
NP_046816.1. NC_001899.1.

3D structure databases

ProteinModelPortalO71155.
SMRO71155. Positions 395-808.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1449602.
1449606.

Family and domain databases

InterProIPR016184. Capsid/spike_ssDNA_virus.
IPR003433. Capsid_VP4_densovirus.
IPR013607. Parvovirus_coat_VP1_N.
[Graphical view]
PfamPF02336. Denso_VP4. 1 hit.
PF08398. Parvo_coat_N. 1 hit.
[Graphical view]
SUPFAMSSF88645. Capsid/spike_ssDNA_virus. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPSD_DSDNV
AccessionPrimary (citable) accession number: O71155
Secondary accession number(s): O92824
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: August 1, 1998
Last modified: May 31, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program