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Protein
Submitted name:

CD44 antigen

Gene

Cd44

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-1474228 Degradation of the extracellular matrix
R-RNO-202733 Cell surface interactions at the vascular wall
R-RNO-216083 Integrin cell surface interactions
R-RNO-2160916 Hyaluronan uptake and degradation
R-RNO-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 antigenImported
Submitted name:
CD44 antigen, isoform CRA_fImported
Submitted name:
Cd44 proteinImported
Submitted name:
Glycoprotein CD44sImported
Gene namesi
Name:Cd44Imported
ORF Names:rCG_26920Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi2307 Cd44

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei272 – 293HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501430656622 – 364Sequence analysisAdd BLAST343

Expressioni

Gene expression databases

BgeeiENSRNOG00000006094
ExpressionAtlasiO70509 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 124LinkInterPro annotationAdd BLAST90

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP Eukaryota
ENOG4111S6T LUCA
GeneTreeiENSGT00530000063822
HOVERGENiHBG003850

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR001231 CD44_antigen
IPR016187 CTDL_fold
IPR000538 Link_dom
PANTHERiPTHR10225:SF6 PTHR10225:SF6, 2 hits
PfamiView protein in Pfam
PF00193 Xlink, 1 hit
PRINTSiPR00658 CD44
PR01265 LINKMODULE
SMARTiView protein in SMART
SM00445 LINK, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS01241 LINK_1, 1 hit
PS50963 LINK_2, 1 hit

Sequencei

Sequence statusi: Complete.

O70509-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKVWWHTAW GLLCLLQLSL AQQQIDLNIT CRYAGVFHVE KNGRYSISRT
60 70 80 90 100
EAADLCEAFN TTLPTMAQME LALSKGFETC RYGFIEGHVV IPRIHPNAIC
110 120 130 140 150
AANNTGVYIL LASNTSHYDT YCFNASAPLE EDCTSVTDLP NSFDGPVTIT
160 170 180 190 200
IVNRDGTRYS KKGEYRTHQE DIDASNIIDE DVSSGSTIEK STPEGYILHT
210 220 230 240 250
DLPTSQPTGD RDDAFFIGST LATSDGDSSM DPRGGFDTVT HGSELAGHSS
260 270 280 290 300
GNQDSGVTTT SGPARRPQIP EWLIILASLL ALALILAVCI AVNSRRRCGQ
310 320 330 340 350
KKKLVINSGN GTVEDRKPSE LNGEASKSQE MVHLVNKEPT ETPDQFMTAD
360
ETRNLQSVDM KIGV
Length:364
Mass (Da):39,725
Last modified:August 1, 1998 - v1
Checksum:iBA249776C4419AA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109112 Genomic DNA No translation available.
AF065147 mRNA Translation: AAC17117.1
BC061531 mRNA Translation: AAH61531.1
BC085703 mRNA Translation: AAH85703.1
BC107949 mRNA Translation: AAI07950.1
BC127485 mRNA Translation: AAI27486.1
CH473949 Genomic DNA Translation: EDL79653.1
RefSeqiXP_006234693.1, XM_006234631.3
UniGeneiRn.1120

Genome annotation databases

EnsembliENSRNOT00000009073; ENSRNOP00000009073; ENSRNOG00000006094
GeneIDi25406

Similar proteinsi

Entry informationi

Entry nameiO70509_RAT
AccessioniPrimary (citable) accession number: O70509
Secondary accession number(s): D4A7E6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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