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Protein
Submitted name:

Myeloid zinc finger protein-2

Gene

Mzf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Myeloid zinc finger protein-2Imported
Gene namesi
Name:Mzf1Imported
Synonyms:MZF-2Imported, Zfp98Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107457. Mzf1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO70162.
PRIDEiO70162.

PTM databases

PhosphoSiteiO70162.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069122.

Structurei

3D structure databases

ProteinModelPortaliO70162.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini124 – 20683SCAN boxInterPro annotationAdd
BLAST
Domaini436 – 46328C2H2-typeInterPro annotationAdd
BLAST
Domaini464 – 49128C2H2-typeInterPro annotationAdd
BLAST
Domaini492 – 51928C2H2-typeInterPro annotationAdd
BLAST
Domaini520 – 54223C2H2-typeInterPro annotationAdd
BLAST
Domaini565 – 59228C2H2-typeInterPro annotationAdd
BLAST
Domaini593 – 62028C2H2-typeInterPro annotationAdd
BLAST
Domaini621 – 64828C2H2-typeInterPro annotationAdd
BLAST
Domaini649 – 67628C2H2-typeInterPro annotationAdd
BLAST
Domaini677 – 70428C2H2-typeInterPro annotationAdd
BLAST
Domaini705 – 73228C2H2-typeInterPro annotationAdd
BLAST
Domaini733 – 76028C2H2-typeInterPro annotationAdd
BLAST
Domaini761 – 78828C2H2-typeInterPro annotationAdd
BLAST
Domaini789 – 81426C2H2-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains SCAN box domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O70162-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSTKHMAHI EFPRISGVWL ACQCLFPRVS SSWRRSRMKG HSMALSQHSL
60 70 80 90 100
PLAVLITHAL YYSFPRDRHW PQRPDLVLLM RPTVLGSSGC APPENEPALV
110 120 130 140 150
KLEDSDSDDE REDILWDPGL EAARLRFRCF RYEDAIGPQE ALAQLRELCH
160 170 180 190 200
QWLRPEVHSK EQVLELLVLE QFLGALPPEI QAQVQGQWPG SPEEAAALVD
210 220 230 240 250
RLRWELDGPR KWVTVQVQGK EVLSEKMEPS SFQPRPHIKL QTPDPGAETP
260 270 280 290 300
QGAMQELPLN LPMKEETELL GNPELLESGP LPAAQEAAAT LLPKETQGHG
310 320 330 340 350
TTLDQTSPHS DTEPDVPPWS EDPMPLWHEE VGGIFSPGFT LQMDSITAEP
360 370 380 390 400
DMMSPHLHVP WDLDMASLSG QIQSPTTEGG FAHALVLPSD PGGEQDPACE
410 420 430 440 450
DPCPSVGPAL VATRWHAPRG RSQSHPRSGT GAMRGGRCDV CGKVFSQRSN
460 470 480 490 500
LLRHQKIHTG ERPFVCGECG RSFSRSSHLL RHQLTHTEER PFVCRDCGQG
510 520 530 540 550
FVRSARLEEH RRVHTGEQPF RCTECGQSFR QRSNLLQHQR IHGDPPGPAP
560 570 580 590 600
SILPLAGVPE PPGPFPCSEC CESFPRRAVL LEHQAVHTGD KSFGCVECGE
610 620 630 640 650
RFGRRSVLLQ HRRVHSGERP FACAECGQSF RQRSNLTQHQ RIHTGERAFA
660 670 680 690 700
CAECGKTFRQ RATLTQHLCV HTGEKPFACP ECGQRFSQRL KLTRHQRTHT
710 720 730 740 750
GEKPYCCGEC DLGFTQVSRL TEHQRIHTGE RPFACPECGQ SFRQHANLTQ
760 770 780 790 800
HRRIHTGERP YACAECGKAF RQRPTLTQHL RTHRHEKPFA CQDCGRRFNQ
810
STKLIQHQRV HSTE
Length:814
Mass (Da):91,668
Last modified:August 1, 1998 - v1
Checksum:iED3CC6C02CD83B71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007407 mRNA. Translation: BAA25190.1.
UniGeneiMm.10103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007407 mRNA. Translation: BAA25190.1.
UniGeneiMm.10103.

3D structure databases

ProteinModelPortaliO70162.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069122.

PTM databases

PhosphoSiteiO70162.

Proteomic databases

PaxDbiO70162.
PRIDEiO70162.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:107457. Mzf1.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A novel form of the myeloid-specific zinc finger protein (MZF-2)."
    Murai K., Murakami H., Nagata S.
    Genes Cells 2:581-591(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO70162_MOUSE
AccessioniPrimary (citable) accession number: O70162
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.