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Protein
Submitted name:

Alpha-1-microglobulin/bikunin

Gene
N/A
Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiI02.005.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-1-microglobulin/bikuninImported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricognathiCaviidaeCavia

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500415990817 – 352Sequence analysisAdd BLAST336

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000009411.

Structurei

3D structure databases

ProteinModelPortaliO70160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini231 – 281BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51
Domaini287 – 337BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

Sequence similaritiesi

Contains 2 BPTI/Kunitz inhibitor domains.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4295. Eukaryota.
ENOG410XQNP. LUCA.
HOGENOMiHOG000001572.
HOVERGENiHBG000225.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
4.10.410.10. 2 hits.
InterProiIPR002968. A1-microglobln.
IPR029856. AMBP.
IPR012674. Calycin.
IPR011038. Calycin-like.
IPR002223. Kunitz_BPTI.
IPR002345. Lipocalin.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
IPR020901. Prtase_inh_Kunz-CS.
[Graphical view]
PANTHERiPTHR10083:SF18. PTHR10083:SF18. 1 hit.
PfamiPF00014. Kunitz_BPTI. 2 hits.
PF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR01215. A1MCGLOBULIN.
PR00759. BASICPTASE.
PR00179. LIPOCALIN.
SMARTiSM00131. KU. 2 hits.
[Graphical view]
SUPFAMiSSF50814. SSF50814. 1 hit.
SSF57362. SSF57362. 2 hits.
PROSITEiPS00280. BPTI_KUNITZ_1. 2 hits.
PS50279. BPTI_KUNITZ_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O70160-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWGAEALLLL LGSCLAISVN PVLTLPDDIQ VQENFDESRM YGKWYSLAIG
60 70 80 90 100
STCPWLKRIK DRLSVDTMVL GKGATEAQMS TTRTHWRRGV CERTSGFYEK
110 120 130 140 150
TDTAGKYLYS NPKWNLTMES YVVHTNYDEY ATVLTKKFSR HHGPTITAKL
160 170 180 190 200
YGREPQLRDS LLQGFREMAL SVGIPEDSIF TMANRGECIP GEQIPQPTPA
210 220 230 240 250
LRARRAVLLQ EDEGSGAGQP VTDFTKKEDS CQLGHSAGPC LGLFKRYFYN
260 270 280 290 300
GSSMACEIFH YGGCLGNGNN FNSEKECLQT CRTVAACNLP IVPGPCQGSA
310 320 330 340 350
QLWAFDAIKG KCVRFTYGGC QGNGNKFYSE KECKEYCGAP GDGDEELLRF

SN
Length:352
Mass (Da):39,033
Last modified:August 1, 1998 - v1
Checksum:iBAA7447B574C2FAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006444 mRNA. Translation: BAA25305.1.
RefSeqiNP_001166307.1. NM_001172836.1.

Genome annotation databases

GeneIDi100379539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006444 mRNA. Translation: BAA25305.1.
RefSeqiNP_001166307.1. NM_001172836.1.

3D structure databases

ProteinModelPortaliO70160.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000009411.

Protein family/group databases

MEROPSiI02.005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100379539.

Organism-specific databases

CTDi259.

Phylogenomic databases

eggNOGiKOG4295. Eukaryota.
ENOG410XQNP. LUCA.
HOGENOMiHOG000001572.
HOVERGENiHBG000225.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
4.10.410.10. 2 hits.
InterProiIPR002968. A1-microglobln.
IPR029856. AMBP.
IPR012674. Calycin.
IPR011038. Calycin-like.
IPR002223. Kunitz_BPTI.
IPR002345. Lipocalin.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
IPR020901. Prtase_inh_Kunz-CS.
[Graphical view]
PANTHERiPTHR10083:SF18. PTHR10083:SF18. 1 hit.
PfamiPF00014. Kunitz_BPTI. 2 hits.
PF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR01215. A1MCGLOBULIN.
PR00759. BASICPTASE.
PR00179. LIPOCALIN.
SMARTiSM00131. KU. 2 hits.
[Graphical view]
SUPFAMiSSF50814. SSF50814. 1 hit.
SSF57362. SSF57362. 2 hits.
PROSITEiPS00280. BPTI_KUNITZ_1. 2 hits.
PS50279. BPTI_KUNITZ_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO70160_CAVPO
AccessioniPrimary (citable) accession number: O70160
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: October 5, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.