Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

30S ribosomal protein S12

Gene

rpsL1

more
Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

With S4 and S5 plays an important role in translational accuracy.UniRule annotation
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12UniRule annotation
Gene namesi
Name:rpsL1UniRule annotation
Ordered Locus Names:aq_1834
AND
Name:rpsL2UniRule annotation
Ordered Locus Names:aq_735
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001461661 – 12830S ribosomal protein S12Add BLAST128

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei893-methylthioaspartic acidBy similarity1

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiO70089.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.UniRule annotation

Protein-protein interaction databases

STRINGi224324.aq_1834.

Structurei

3D structure databases

ProteinModelPortaliO70089.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uS12 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UKE. Bacteria.
COG0048. LUCA.
HOGENOMiHOG000040063.
InParanoidiO70089.
KOiK02950.
OMAiKRGVCTA.
OrthoDBiPOG091H025P.

Family and domain databases

CDDicd03368. Ribosomal_S12. 1 hit.
HAMAPiMF_00403_B. Ribosomal_S12_B. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiView protein in Pfam
PF00164. Ribosom_S12_S23. 1 hit.
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00055. RIBOSOMAL_S12. 1 hit.

Sequencei

Sequence statusi: Complete.

O70089-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTFNQLVKY GREKRKKKSK APALQGCPQK RGVCVRVYTV TPKKPNSALR
60 70 80 90 100
KVARVRLSNG IEVTAYIPGE GHNLQEHSIV LVRGGRVKDL PGVRYKIIRG
110 120
ALDAAGVEGR RQSRSKYGTK RPKEEKGG
Length:128
Mass (Da):14,207
Last modified:August 1, 1998 - v1
Checksum:i64731C4F359ECCD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07655.1.
AE000657 Genomic DNA. Translation: AAC06910.1.
PIRiH70457.
RefSeqiNP_213505.1. NC_000918.1.
NP_214257.1. NC_000918.1.
WP_010880443.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06910; AAC06910; aq_735.
AAC07655; AAC07655; aq_1834.
GeneIDi1193394.
1193497.
KEGGiaae:aq_1834.
aae:aq_735.
PATRICifig|224324.8.peg.1415.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRS12_AQUAE
AccessioniPrimary (citable) accession number: O70089
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: June 7, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families