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Protein
Submitted name:

Putative two-component sensor

Gene

SCO5829

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative two-component sensorImported
Gene namesi
Ordered Locus Names:SCO5829Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 56HelicalSequence analysisAdd BLAST24
Transmembranei195 – 213HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO5829.

Structurei

3D structure databases

ProteinModelPortaliO70005.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini433 – 544Histidine kinaseInterPro annotationAdd BLAST112

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105CEQ. Bacteria.
COG3290. LUCA.
HOGENOMiHOG000241935.
InParanoidiO70005.
KOiK02476.
OMAiHYQNGWL.
OrthoDBiPOG091H06U8.
PhylomeDBiO70005.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR033463. sCache_3.
IPR029151. Sensor-like.
IPR004358. Sig_transdc_His_kin-like_C.
IPR016120. Sig_transdc_His_kin_SpoOB.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00989. PAS. 1 hit.
PF17203. sCache_3_2. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF103190. SSF103190. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF55890. SSF55890. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O70005-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPAPRTVMA MSSTPPVRRL RLGLPRRVFS QVLLMQLAIA AGVAVLATGL
60 70 80 90 100
FLAPLGDQLD DQAMRRALAI AQTTAQQPQV VRDLRTTRPT ANGPVQREAE
110 120 130 140 150
RVREATRAEY VVVMDRQGVR WSHTDPERIG EVVSTDPGQA LAGREVMEID
160 170 180 190 200
DGTLGRSARG KVPLRDGDGE IVGAVSVGIA YDSVRARLIH AIPGLFAYAG
210 220 230 240 250
GALAVGALAS WIISRRVQRQ TRDLAFSDIA GLLAEREAML HGIREGVVAL
260 270 280 290 300
DRGGRVRLLN DEAQRLLGIG GEAVGRSPDE ALGAGRTADV LAGRVTGTDL
310 320 330 340 350
LTVRGQRVLV ANRMPTDDGG AVATLRDRTE LEQLGRELDS TRGLIDALRA
360 370 380 390 400
QDHEHANRMH TLLGLLELEM YDDAVEFVGE VVGDHRVTAE QITERIHDPL
410 420 430 440 450
LAALLVGKAT VAAERGVALR VSDRTRLPDR LVDPRGLVTI VGNLVDNALD
460 470 480 490 500
AAAGTAHARV EVELRAEGRA ATLTVRDTGP GIAADHRELV FAAGWSTKEP
510 520 530 540 550
PAHRERGIGL PLVRRLAERQ GGSATVGEAY GGGAEFVVVL PEALTEAAPE
560
PALTVPVTTA AEEESR
Length:566
Mass (Da):60,377
Last modified:August 1, 1998 - v1
Checksum:i4488E12E6F02079A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939125 Genomic DNA. Translation: CAA18527.1.
PIRiT35203.
RefSeqiNP_629952.1. NC_003888.3.
WP_011030484.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAA18527; CAA18527; CAA18527.
GeneIDi1101271.
KEGGisco:SCO5829.
PATRICi23741558. VBIStrCoe124346_5926.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939125 Genomic DNA. Translation: CAA18527.1.
PIRiT35203.
RefSeqiNP_629952.1. NC_003888.3.
WP_011030484.1. NC_003888.3.

3D structure databases

ProteinModelPortaliO70005.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO5829.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA18527; CAA18527; CAA18527.
GeneIDi1101271.
KEGGisco:SCO5829.
PATRICi23741558. VBIStrCoe124346_5926.

Phylogenomic databases

eggNOGiENOG4105CEQ. Bacteria.
COG3290. LUCA.
HOGENOMiHOG000241935.
InParanoidiO70005.
KOiK02476.
OMAiHYQNGWL.
OrthoDBiPOG091H06U8.
PhylomeDBiO70005.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR033463. sCache_3.
IPR029151. Sensor-like.
IPR004358. Sig_transdc_His_kin-like_C.
IPR016120. Sig_transdc_His_kin_SpoOB.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00989. PAS. 1 hit.
PF17203. sCache_3_2. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF103190. SSF103190. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF55890. SSF55890. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO70005_STRCO
AccessioniPrimary (citable) accession number: O70005
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.