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Protein

DNA topoisomerase (ATP-hydrolyzing)

Gene

SCO5822

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP-dependent breakage, passage and rejoining of double-stranded DNA.SAAS annotation

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, TopoisomeraseSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA topoisomerase (ATP-hydrolyzing)SAAS annotation (EC:5.99.1.3SAAS annotation)
Gene namesi
Ordered Locus Names:SCO5822Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PRIDEiO69998

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO5822

Structurei

3D structure databases

ProteinModelPortaliO69998
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini480 – 594ToprimInterPro annotationAdd BLAST115

Phylogenomic databases

eggNOGiENOG4105C7D Bacteria
COG0187 LUCA
HOGENOMiHOG000075154
InParanoidiO69998
KOiK02470
OMAiNIRYKDS
OrthoDBiPOG091H03L6
PhylomeDBiO69998

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di3.30.230.10, 1 hit
3.30.565.10, 1 hit
3.40.50.670, 1 hit
InterProiView protein in InterPro
IPR002288 DNA_gyrase_B_C
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR001241 Topo_IIA
IPR013760 Topo_IIA-like_dom_sf
IPR013759 Topo_IIA_B_C
IPR013506 Topo_IIA_bsu_dom2
IPR018522 TopoIIA_CS
IPR006171 TOPRIM_domain
PANTHERiPTHR10169 PTHR10169, 1 hit
PfamiView protein in Pfam
PF00204 DNA_gyraseB, 1 hit
PF00986 DNA_gyraseB_C, 1 hit
PF02518 HATPase_c, 1 hit
PF01751 Toprim, 1 hit
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SM00433 TOP2c, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
SSF56719 SSF56719, 1 hit
PROSITEiView protein in PROSITE
PS00177 TOPOISOMERASE_II, 1 hit
PS50880 TOPRIM, 1 hit

Sequencei

Sequence statusi: Complete.

O69998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAETSVPST ALLAGADRDG SNYTARHLLV LEGLEAVRKR PGMYIGSTDS
60 70 80 90 100
RGLMHCLWEI IDNSVDEALG GYCDHIEVIL HDDASVEVRD NGRGIPVDVE
110 120 130 140 150
PKTGLSGVEV VMTKLHAGGK FGGGAYAASG GLHGVGASVV NALSARLDIE
160 170 180 190 200
VDLGGHTHAI SFRRGVPGTF AKAGPDAKFE AGSGLRKVKK VPKSRRGTRV
210 220 230 240 250
RYWADRQIFL KDAKLSLDNL HQRARQTAFL VPGLTIVVRD EFGLGDGGSK
260 270 280 290 300
GEESFRFDGG ISEFCEFLAG DRPVCDVLRF SGQGSFKETV PVLDEDGQMT
310 320 330 340 350
PSEVTRDLGV DVALRWGTGY DTTVRSFVNI IATPKGGTHV AGFEQAVAKT
360 370 380 390 400
MNEVLRTKKM LRVAEDDIVK DDALEGLTAV VTVRLAEPQF EGQTKEVLGT
410 420 430 440 450
SAARRIVNNV ISRELKAFLT STKRDAAQQA RVVMEKAVAA ARTRIAARQH
460 470 480 490 500
KDAQRRKTAL ESSSLPAKLA DCRSDDVDRS ELFIVEGDSA LGTAKLARNS
510 520 530 540 550
EFQALLPIRG KILNVQKSSV TDMLKNAECG AIIQVIGAGS GRTFDIDAAR
560 570 580 590 600
YGKIIMMTDA DVDGSHIRTL LLTLFHRYMR PMVEAGRVFA AVPPLHRIEL
610 620 630 640 650
VQPKKGQDKY VYTYSDRELR DKLMEFQSKN IRYKDSIQRY KGLGEMDADQ
660 670 680 690 700
LAETTMDPRR RTLRRINLTD LDSAEQVFDL LMGNDVAPRK EFISSSAATL

DRSRIDA
Length:707
Mass (Da):77,270
Last modified:August 1, 1998 - v1
Checksum:i1A5427EB8EFB6661
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939125 Genomic DNA Translation: CAA18520.1
PIRiT35196
RefSeqiNP_629945.1, NC_003888.3
WP_003973199.1, NC_003888.3

Genome annotation databases

EnsemblBacteriaiCAA18520; CAA18520; CAA18520
GeneIDi1101264
KEGGisco:SCO5822
PATRICifig|100226.15.peg.5919

Similar proteinsi

Entry informationi

Entry nameiO69998_STRCO
AccessioniPrimary (citable) accession number: O69998
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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