ID   O69922_STRCO            Unreviewed;       367 AA.
AC   O69922;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAA19601.1};
GN   OrderedLocusNames=SCO6390 {ECO:0000313|EMBL:CAA19601.1};
GN   ORFNames=SC3C8.09 {ECO:0000313|EMBL:CAA19601.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAA19601.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAA19601.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL939127; CAA19601.1; -; Genomic_DNA.
DR   PIR; T34884; T34884.
DR   RefSeq; NP_630481.1; NC_003888.3.
DR   AlphaFoldDB; O69922; -.
DR   STRING; 100226.gene:17764049; -.
DR   PaxDb; 100226-SCO6390; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_045535_1_1_11; -.
DR   InParanoid; O69922; -.
DR   OrthoDB; 311904at2; -.
DR   PhylomeDB; O69922; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        40..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          140..365
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   367 AA;  39382 MW;  667A671A305B158A CRC64;
     MDRFQAGDLP DRTARMAVGA AVALVLVIIL ADVISPKGVY LSPMLVVAPA LTTAFAGPRL
     TAGVALVAIA AQMVAASLTG SALSAARLWQ LSALVVVSIL LIFFSYVRQR RARQLSRARR
     VAEAAQRVLL RPPPERVGPL RIGWQYLTAE DDTQFGGDLF AVTRRRPDSS RVIIGDVRGH
     GLPAISEASA ALGSFREAAR RCARLDELAL ILEESIGWDL EEGGEGPGQE DEHFVTALLL
     DLPDAHDHAS MISCGHSPPL LVHSDGRVTT AHCDPAPPLG LGYLSLTGVR IQTVEYAVGD
     TLLLYTDGVI EARSPQGEFY PLAKRVRSFP YSESPEVLLK RLRQDLLAHT GGHLSDDAAL
     LAVTRAN
//