ID   DAPB2_RHIME             Reviewed;         242 AA.
AC   O69783;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   16-JUN-2009, entry version 56.
DE   RecName: Full=Dihydrodipicolinate reductase;
DE            Short=DHPR;
DE            EC=1.3.1.26;
DE   Flags: Fragment;
GN   Name=dapB;
OS   Rhizobium meliloti (Sinorhizobium meliloti).
OG   Plasmid pRmeGR4b.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=382;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GR4;
RX   MEDLINE=20353121; PubMed=10896225; DOI=10.1007/s002030000169;
RA   Garcia-Rodriguez F.M., Zekri S., Toro N.;
RT   "Characterization of the Sinorhizobium meliloti genes encoding a
RT   functional dihydrodipicolinate synthase (dapA) and dihydrodipicolinate
RT   reductase (dapB).";
RL   Arch. Microbiol. 173:438-444(2000).
CC   -!- CATALYTIC ACTIVITY: 2,3,4,5-tetrahydrodipicolinate + NAD(P)(+) =
CC       2,3-dihydrodipicolinate + NAD(P)H.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; tetrahydrodipicolinate from L-aspartate: step 4/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the dihydrodipicolinate reductase family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA10958.1; Type=Frameshift; Positions=Several;
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DR   EMBL; AJ222715; CAA10958.1; ALT_FRAME; Genomic_DNA.
DR   HSSP; P04036; 1DRW.
DR   BRENDA; 1.3.1.26; 142.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0008839; F:dihydrodipicolinate reductase activity; IEA:HAMAP.
DR   GO; GO:0019877; P:diaminopimelate biosynthetic process; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00102; -; 1.
DR   InterPro; IPR000846; DapB.
DR   InterPro; IPR011770; DapB_bac/pln.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR20836; DapB_bac/pln; 1.
DR   Pfam; PF05173; DapB_C; 1.
DR   Pfam; PF01113; DapB_N; 1.
DR   ProDom; PD004105; DapB; 1.
DR   TIGRFAMs; TIGR00036; dapB; 1.
DR   PROSITE; PS01298; DAPB; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Cytoplasm; Diaminopimelate biosynthesis;
KW   Lysine biosynthesis; NADP; Oxidoreductase; Plasmid.
FT   CHAIN         1   >242       Dihydrodipicolinate reductase.
FT                                /FTId=PRO_0000141477.
FT   NON_TER     242    242
SQ   SEQUENCE   242 AA;  24880 MW;  31C962599F153CC5 CRC64;
     MSQMRLVVVG AAGRMGRTLI KAIAENPGCM LSGAVERPGS AAVGQDAGFV AGMASCGVLV
     TDEPGSAFAE ADGVLDFTTP DATAEYSSLA AQVGIVHVVG TTGMEPVHFS KLVRAARTIP
     VVQSGNMSLG VNILAALVQK VAAILDKEWD IEVLEMHHRM KVDAPSGAAL LLGEAAASGR
     QTILSDHYVA GRDGYTGCRT VGTIGFAPCA GXVVGDHKVV FAGAGXRIEL SHIAEDRSLF
     AQ
//