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Protein
Submitted name:

ATP-dependent DNA ligase

Gene

ligC

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligaseImported (EC:6.5.1.1Imported)
Submitted name:
ATP-dependent DNA ligase LigCImported
Gene namesi
Name:ligCImported
Ordered Locus Names:RVBD_3731Imported
ORF Names:LH57_20335Imported, P425_03882Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000003123 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv3731.

Structurei

3D structure databases

ProteinModelPortaliO69698.
SMRiO69698. Positions 8-334.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000222508.
OMAiHERTADC.
OrthoDBiEOG63NMFT.
PhylomeDBiO69698.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O69698-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLPVMPPVS PMLAKSVTAI PPDASYEPKW DGFRSICFRD GDQVELGSRN
60 70 80 90 100
ERPMTRYFPE LVAAIRAELP HRCVIDGEII IATDHGLDFE ALQQRIHPAE
110 120 130 140 150
SRVRMLADRT PASFIAFDLL ALGDDDYTGR PFSERRAALV DAVTGSGADA
160 170 180 190 200
DLSIHVTPAT TDMATAQRWF SEFEGAGLDG VIAKPPHITY QPDKRVMFKI
210 220 230 240 250
KHLRTADCVV AGYRVHKSGS DAIGSLLLGL YQEDGQLASV GVIGAFPMAE
260 270 280 290 300
RRRLLTELQP LVTSFDDHPW NWAAHVAGQR TPRKNEFSRW NVGKDLSFVP
310 320 330 340 350
LRPERVVEVR YDRMEGARFR HTAQFNRWRP DRDPRSCSYA QLERPLTVSL

SDIVPGLR
Length:358
Mass (Da):40,160
Last modified:July 31, 1998 - v1
Checksum:i8EBA33D1A57CAA4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003248 Genomic DNA. Translation: AFN51754.1.
CP009480 Genomic DNA. Translation: AIR16521.1.
JLDD01000048 Genomic DNA. Translation: KBJ24805.1.
RefSeqiNP_218248.1. NC_000962.3.
YP_006517225.1. NC_018143.2.

Genome annotation databases

EnsemblBacteriaiAFN51754; AFN51754; RVBD_3731.
KBJ24805; KBJ24805; P425_03882.
GeneIDi885771.
KEGGimtu:Rv3731.
mtv:RVBD_3731.
PATRICi18156907. VBIMycTub87468_4159.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003248 Genomic DNA. Translation: AFN51754.1.
CP009480 Genomic DNA. Translation: AIR16521.1.
JLDD01000048 Genomic DNA. Translation: KBJ24805.1.
RefSeqiNP_218248.1. NC_000962.3.
YP_006517225.1. NC_018143.2.

3D structure databases

ProteinModelPortaliO69698.
SMRiO69698. Positions 8-334.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv3731.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFN51754; AFN51754; RVBD_3731.
KBJ24805; KBJ24805; P425_03882.
GeneIDi885771.
KEGGimtu:Rv3731.
mtv:RVBD_3731.
PATRICi18156907. VBIMycTub87468_4159.

Phylogenomic databases

HOGENOMiHOG000222508.
OMAiHERTADC.
OrthoDBiEOG63NMFT.
PhylomeDBiO69698.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  4. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.

Entry informationi

Entry nameiO69698_MYCTU
AccessioniPrimary (citable) accession number: O69698
Secondary accession number(s): I6XI27
Entry historyi
Integrated into UniProtKB/TrEMBL: July 31, 1998
Last sequence update: July 31, 1998
Last modified: March 31, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.